A simple model of cardiac mitochondrial respiration with experimental validation

Bachar Tarraf; Emmanuel Suraniti; Camille Colin; Stéphane Arbault; Philippe Diolez; Michael Leguèbe; Yves Coudière; Bachar Tarraf; Emmanuel Suraniti; Camille Colin; Stéphane Arbault; Philippe Diolez; Michael Leguèbe; Yves Coudière

doi:10.3934/mbe.2021291

Mathematical Biosciences and Engineering

2021, Volume 18, Issue 5: 5758-5789. doi: 10.3934/mbe.2021291

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Research article Special Issues

A simple model of cardiac mitochondrial respiration with experimental validation

1.
Inria Bordeaux-Sud-Ouest, team CARMEN, Talence, France
2.
IHU Liryc, Fondation Bordeaux Université, Pessac, France
3.
Institut de Mathématiques de Bordeaux, UMR CNRS 5251, Talence, France
4.
Université de Bordeaux, Bordeaux, France
5.
ISM, CNRS UMR 5255, Bordeaux, France
6.
INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U-1045, Bordeaux, France

Received: 12 February 2021 Accepted: 06 June 2021 Published: 25 June 2021

Cardiac mitochondria are intracellular organelles that play an important role in energy metabolism and cellular calcium regulation. In particular, they influence the excitation-contraction cycle of the heart cell. A large number of mathematical models have been proposed to better understand the mitochondrial dynamics, but they generally show a high level of complexity, and their parameters are very hard to fit to experimental data.

We derived a model based on historical free energy-transduction principles, and results from the literature. We proposed simple expressions that allow to reduce the number of parameters to a minimum with respect to the mitochondrial behavior of interest for us. The resulting model has thirty-two parameters, which are reduced to twenty-three after a global sensitivity analysis of its expressions based on Sobol indices.

We calibrated our model to experimental data that consists of measurements of mitochondrial respiration rates controlled by external ADP additions. A sensitivity analysis of the respiration rates showed that only seven parameters can be identified using these observations. We calibrated them using a genetic algorithm, with five experimental data sets. At last, we used the calibration results to verify the ability of the model to accurately predict the values of a sixth dataset.

Results show that our model is able to reproduce both respiration rates of mitochondria and transitions between those states, with very low variability of the parameters between each experiment. The same methodology may apply to recover all the parameters of the model, if corresponding experimental data were available.

Keywords:

Citation: Bachar Tarraf, Emmanuel Suraniti, Camille Colin, Stéphane Arbault, Philippe Diolez, Michael Leguèbe, Yves Coudière. A simple model of cardiac mitochondrial respiration with experimental validation[J]. Mathematical Biosciences and Engineering, 2021, 18(5): 5758-5789. doi: 10.3934/mbe.2021291

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Abstract

1. Introduction

Fractional calculus is the study of integrals and derivatives of any arbitrary real or complex order. Its origin goes far back in 1695 when Leibniz and l'Hospital started discussion on the meaning of semi-derivative. The $17^{th}$ century witnessed the attention of this debate by many researchers working in the field of mathematics. Seeking in the formulation of fractional derivative/integral formulas Riemann and Liouville obtained their definitions with complementary functions. Later by Sonin and Letnikov along with others worked out the final form of fractional integral operator named Riemann-Liouville fractional integral/derivative operator, see ^[1,2]. After this definition of fractional integral/derivative operator the subject of fractional calculus become prominent in generalizing and extending the concepts of calculus and their applications. From the last few years, use of fractional calculus is also followed by scientists from various fields of engineering, sciences and economics. Some fractional integral operators have also been introduced in recent past see ^[3,4,5]. By applying fractional operators, extensive research has been carried out to establish various inequalities with motivating results, see ^[6,7,8,9].

Definition 1. ^[10] Let $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Then left-sided and right-sided Riemann-Liouville fractional integrals of a function $\varphi$ of order $\zeta$ where $\Re(\zeta) > 0$ are given by

$\begin{equation} I_{\varrho_{1}^+}^{\zeta}\varphi(x) = \frac{1}{\Gamma({\zeta})}\int_{\varrho_{1}}^{x}(x-t)^{\zeta-1}\varphi(t)dt, \quad x > \varrho_{1}, \end{equation}$

(1.1)

and

$\begin{equation} I_{\varrho_{2}^-}^{\zeta}\varphi(x) = \frac{1}{\Gamma({\zeta})}\int_{x}^{\varrho_{2}}(t-x)^{\zeta-1}\varphi(t)dt, \quad x < \varrho_{2}. \end{equation}$

(1.2)

The $k$ -analogue of the Riemann-Liouville fractional integral is defined as follows:

Definition 2. ^[11] Let $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Then $k$ -fractional Riemann-Liouville integrals of order $\zeta$ where $\Re(\zeta) > 0$ , $k > 0$ , are given by

$\begin{equation} _{k}I_{\varrho_{1}^+}^{\zeta}\varphi(x) = \frac{1}{k\Gamma_{k}({\zeta})}\int_{\varrho_{1}}^{x}(x-t)^{\frac{\zeta}{k}-1}\varphi(t)dt, \quad x > \varrho_{1}, \end{equation}$

(1.3)

and

$\begin{equation} _{k}I_{\varrho_{2}^-}^{\zeta}\varphi(x) = \frac{1}{k\Gamma_{k}({\zeta})}\int_{x}^{\varrho_{2}}(t-x)^{\frac{\zeta}{k}-1}\varphi(t)dt, \quad x < \varrho_{2}, \end{equation}$

(1.4)

where $\Gamma_{k}(.)$ is defined by ^[12]:

$\begin{align} \Gamma_{k}(\zeta) = \int_{0}^{\infty}t^{\zeta-1}e^{-\frac{t^{k}}{k}}dt, \quad \Re(\zeta) > 0. \end{align}$

The generalized Riemann-Liouville fractional integrals via a monotonically increasing function are given as follows:

Definition 3. ^[1] Let $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Also let $\psi$ be an increasing and positive monotone function on $(\varrho_{1}, \varrho_{2}]$ , further $\psi$ has a continuous derivative $\psi'$ on $(\varrho_{1}, \varrho_{2})$ . The left as well as right fractional integral operators of order $\zeta$ where $\Re(\zeta) > 0$ of $\varphi$ with respect to $\psi$ on $[\varrho_{1}, \varrho_{2}]$ are given by

$\begin{equation} ^{\psi}I_{\varrho_{1}^+}^{\zeta}\varphi(x) = \frac{1}{\Gamma({\zeta})}\int_{\varrho_{1}}^{x}\psi^\prime(t)(\psi(x)-\psi(t))^{\zeta-1}\varphi(t)dt, \quad x > \varrho_{1}, \end{equation}$

(1.5)

and

$\begin{equation} ^{\psi}I_{\varrho_{2}^-}^{\zeta}\varphi(x) = \frac{1}{\Gamma({\zeta})}\int_{x}^{\varrho_{2}}\psi^\prime(t)(\psi(t)-\psi(x))^{\zeta-1}\varphi(t)dt, \quad x < \varrho_{2}. \end{equation}$

(1.6)

The $k$ -analogues of the above generalized Riemann-Liouville fractional integrals are defined as follows:

Definition 4. ^[13] Let $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Also let $\psi$ be an increasing and positive monotone function on $(\varrho_{1}, \varrho_{2}]$ , further $\psi$ has a continuous derivative $\psi'$ on $(\varrho_{1}, \varrho_{2})$ . Therefore left as well as right $k$ -fractional integral operators of order $\zeta$ where $\Re(\zeta) > 0$ of $\varphi$ with respect to $\psi$ on $[\varrho_{1}, \varrho_{2}]$ are given by

$\begin{equation} _{k}^{\psi}I_{\varrho_{1}^+}^{\zeta}\varphi(x) = \frac{1}{k\Gamma_{k}({\zeta})}\int_{\varrho_{1}}^{x}\psi^\prime(t)(\psi(x)-\psi(t))^{\frac{\zeta}{k}-1}\varphi(t)dt, \quad x > \varrho_{1}, \end{equation}$

(1.7)

and

$\begin{equation} _{k}^{\psi}I_{\varrho_{2}^-}^{\zeta}\varphi(x) = \frac{1}{k\Gamma_{k}({\zeta})}\int_{x}^{\varrho_{2}}\psi^\prime(t)(\psi(t)-\psi(x))^{\frac{\zeta}{k}-1}\varphi(t)dt, \quad x < \varrho_{2}. \end{equation}$

(1.8)

For a detailed study of fractional integrals we refer the readers to ^[2,14]. Next, we give the definition of exponentially $(\alpha, h-m)$ -convex function as follows:

Definition 5. ^[15] Let $J\subseteq\mathbb{R}$ be an interval containing $(0, 1)$ and let $h:J\rightarrow \mathbb{R}$ be a non-negative function. A function $\varphi:[0, \varrho_{2}]\rightarrow \mathbb{R}$ is called exponentially $(\alpha, h-m)$ -convex function, if for all $x, y\in[0, \varrho_{2}]$ , $t\in(0, 1)$ , $(\alpha, m)$ $\in(0, 1]^{2}$ and $\eta\in\mathbb{R}$ one has

$\begin{align} &\varphi(tx+m(1-t)y)\leq h(t^{\alpha})\frac{\varphi(x)}{e^{\eta x}}+mh(1-t^{\alpha}) \frac{\varphi(y)}{e^{\eta y}}. \end{align}$

(1.9)

The above definition provides some kinds of exponential convexities as follows:

Remark 1. (i) If we substitute $\alpha = 1$ and $h(t) = t^{s}$ , then exponentially $(s, m)$ -convex function in the second sense introduced by Qiang et al. in ^[16] can be obtained.

(ii) If we substitute $\alpha = m = 1$ and $h(t) = t^{s}$ , then exponentially $s$ -convex function introduced by Mehreen et al. in ^[17] can be obtained.

(iii) If we substitute $\alpha = m = 1$ and $h(t) = t$ , then exponentially convex function introduced by Awan et al. in ^[18] can be obtained.

In ^[19,20], the following Hadamard inequality for convex function $\varphi:[\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ is studied:

$\begin{align} \varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq\frac{1}{\varrho_{2}-\varrho_{1}}\int_{\varrho_{1}}^{\varrho_{2}}\varphi(\nu)d\nu\leq\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}. \end{align}$

(1.10)

If this inequality holds in reverse order, then the function $f$ is called concave function. This inequality was first published by Hermite in 1883 and later Hadamard proved it independently in 1893. Since its occurrence, it is in focus of researchers and had/has been studied for different kinds of convex functions. In past two decades it is generalized by using various types of fractional integral operators and authors have investigated a lot of versions of this inequality, see ^[21,22,23] and references therein. Our aim in this article is to apply the generalized Riemann-Liouville fractional integrals with monotonically increasing function to obtain the Hadamard inequalities for exponentially $(\alpha, h-m)$ -convex functions. Two fractional integral identities are applied to get the error bounds of Hadamard type inequalities. Following two theorems give the fractional versions of Hadamard inequalities for Riemann-Liouville fractional integrals.

Theorem 1. ^[24] Let $\varphi:[\varrho_{1}, \varrho_{2}] \rightarrow \mathbb{R}$ be a positive function with $0\leq\varrho_{1} < \varrho_{2}$ and $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . If $\varphi$ is a convex function on $[\varrho_{1}, \varrho_{2}]$ , then the following fractional integral inequality holds:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq\frac{\Gamma({\zeta}+1)}{2(\varrho_{2}-\varrho_{1})^\zeta}\left[I_{\varrho_{1}^+}^{\zeta}\varphi(\varrho_{2})+I_{\varrho_{2}^-}^{\zeta}\varphi(\varrho_{1})\right]\leq\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}, \end{align}$

(1.11)

with $\zeta > 0$ .

Theorem 2. ^[25] Under the assumptions of Theorem 1, the following fractional integral inequality holds:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq \frac{2^{\zeta-1}\Gamma({\zeta}+1)}{(\varrho_{2}-\varrho_{1})^\zeta}\left[I_{\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^+}^{\zeta}\varphi(\varrho_{2})+I_{\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^-}^{\zeta}\varphi(\varrho_{1})\right]\leq\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}, \end{align}$

(1.12)

with $\zeta > 0$ .

The following theorem gives an error estimation of the inequality (1.11).

Theorem 3. ^[24] Let $\varphi:[\varrho_{1}, \varrho_{2}] \rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ with $\varrho_{1} < \varrho_{2}$ . If $\left|\varphi'\right|$ is convex on $[\varrho_{1}, \varrho_{2}]$ , then the following fractional integral inequality holds:

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma({\zeta}+1)}{2(\varrho_{2}-\varrho_{1})^\zeta}\left[I_{{\varrho_{1}}^+}^{\zeta}\varphi(\varrho_{2})+I_{\varrho_{2}^-}^{\zeta}\varphi(\varrho_{1})\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2(\zeta+1)}\left(1-\frac{1}{2^{\zeta}}\right)[|\varphi'(\varrho_{1})|+|\varphi'(\varrho_{2})|]. \end{align}$

(1.13)

The $k$ -analogues of Theorems 1 and 2 are given in the next two results.

Theorem 4. ^[26] Let $\varphi:[\varrho_{1}, \varrho_{2}] \rightarrow \mathbb{R}$ be a positive function with $0\leq\varrho_{1} < \varrho_{2}$ . If $\varphi$ is a convex function on $[\varrho_{1}, \varrho_{2}]$ , then the following inequality for $k$ -fractional integral holds:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq \frac{\Gamma_{k}({\zeta}+k)}{2(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\left[_{k}I_{\varrho_{1}^+}^{\zeta}\varphi(\varrho_{2})+ \quad _{k}I_{\varrho_{2}^-}^{\zeta}\varphi(\varrho_{1})\right]\leq\frac{\varphi(\varrho_{1})+f(\varrho_{2})}{2}, \end{align}$

(1.14)

with $\zeta > 0$ .

Theorem 5. ^[27] Under the assumptions of Theorem 4, the following inequality for $k$ -fractional integral holds:

$\begin{align} \varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(\varrho_{2}-\varrho_{1})^\frac{\zeta}{k}}\left[_{k}I_{\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^+}^{\zeta}\varphi(\varrho_{2})+ \quad _{k}I_{\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^-}^{\zeta}\varphi(\varrho_{1})\right]\leq\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}, \end{align}$

(1.15)

with $\zeta > 0$ .

An error estimation of the inequality (1.14) is given in the following theorem.

Theorem 6. ^[26] Let $\varphi:[\varrho_{1}, \varrho_{2}] \rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ with $0\leq\varrho_{1} < \varrho_{2}$ . If $\left|\varphi'\right|$ is convex on $[\varrho_{1}, \varrho_{2}]$ , then the following inequality for $k$ -fractional integral holds:

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma_{k}({\zeta}+k)}{2(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\left[_{k}I_{{\varrho_{1}}^+}^{\zeta}\varphi(\varrho_{2})+ \quad _{k}I_{\varrho_{2}^-}^{\zeta}\varphi(\varrho_{1})\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2(\frac{\zeta}{k}+1)}\left(1-\frac{1}{2^{\frac{\zeta}{k}}}\right)[|\varphi'(\varrho_{1})|+|\varphi'(\varrho_{2})|]. \end{align}$

(1.16)

The rest of the paper is organized as follows: In Section 2, we establish Hadamard inequalities for generalized Riemann-Liouville fractional integrals of exponentially $(\alpha, h-m)$ -convex functions. The special cases, associated with previously published results are presented in terms of their generalizations. In Section 3, using two fractional integral identities, the error bounds of fractional Hadamard inequalities are established. Inequalities proved in this article are in line with the results established in ^{[24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39]}.

2. Main results

We give two fractional versions of the Hadamard inequality for exponentially $(\alpha, h-m)$ -convex functions, first one is given in the following theorem.

Theorem 7. Let $\varphi:[\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ be a positive function with $0\leq \varrho_{1} < m\varrho_{2}$ and $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Also suppose that $\varphi$ is exponentially $(\alpha, h-m)$ -convex function on $[\varrho_{1}, \varrho_{2}]$ , such that $\frac{\varrho_{1}}{m}$ , $\frac{\varrho_{2}}{m^{2}}$ $\in[\varrho_{1}, \varrho_{2}]$ . Then, for $\eta\in\mathbb{R}$ , $k > 0$ and $(\alpha, m)\in (0, 1]^{2}$ , the following $k$ -fractional integral inequality holds for operators given in (1.7) and (1.8):

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{\Gamma_{k}({\zeta+k})}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\!_{k}^{\psi}I_{\psi^{-1}(\varrho_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))+g_{2}(\eta)H\left(\frac{1}{2}\right)\\&\times m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)\left( \psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\leq\frac{\zeta}{k}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi(\varrho_{2})}{e^{\eta\varrho_{2}}}\bigg]\\&\int_{0}^{1}h(t^{\alpha})t^{{\frac{\zeta}{k}-1}}dt+\frac{m\zeta}{k}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]\int_{0}^{1}t^{{\frac{\zeta}{k}-1}}H(t)dt, \end{align}$

(2.1)

where $\zeta > 0$ , $H(t) = h(1-t^{\alpha})$ and

$\begin{equation*} g_{1}(\eta) = \begin{cases} {}{e^{-\eta m\varrho_{2}}} & \mathit{\text{if}} \ \eta < 0\\ {}{e^{-\eta \varrho_{1}}} & \mathit{\text{if}} \ \eta > 0 \end{cases}, \quad g_{2}(\eta) = \begin{cases} {}{e^{-\eta \varrho_{2}}} & \mathit{\text{if}} \ \eta < 0\\ {}{e^{\frac{-\eta \varrho_{1}}{m}}} & \mathit{\text{if}} \ \eta > 0 \end{cases} . \end{equation*}$

Proof. From exponentially $(\alpha, h- m)$ -convexity of $\varphi$ , the following inequality holds:

$\begin{equation} \varphi\left(\frac{x+my}{2}\right)\leq {h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(x)}{e^{\eta x}}+mh\left(\frac{2^{\alpha}-1}{2^{\alpha}}\right)\frac{\varphi(y)}{e^{\eta y}}}. \end{equation}$

(2.2)

By setting $x = \varrho_{1}t+m(1-t)\varrho_{2}$ , $y = \frac{\varrho_{1}}{m}(1-t)+\varrho_{2}t$ , $t\in[0, 1]$ , in (2.2) and integrating the resulting inequality over $[0, 1]$ after multiplying with $t^{{\frac{\zeta}{k}-1}}$ , we get

$\begin{align} \frac{k}{\zeta}\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)&\leq h\left(\frac{1}{2^{\alpha}}\right)\int_{0}^{1}\frac{\varphi(\varrho_{1}t+m(1-t)\varrho_{2})}{e^{\eta(\varrho_{1}t+m(1-t)\varrho_{2})}}t^{{\frac{\zeta}{k}-1}}dt\\&+mH\left(\frac{1}{2}\right)\int_{0}^{1}\frac{\varphi\left(\frac{\varrho_{1}}{m}(1-t)+\varrho_{2}t\right)}{e^{\eta\left(\frac{\varrho_{1}}{m}(1-t)+\varrho_{2}t\right)}}t^{{\frac{\zeta}{k}-1}}dt. \end{align}$

(2.3)

By setting $\psi(u) = \varrho_{1}t+m(1-t)\varrho_{2}$ and $\psi(v) = \frac{\varrho_{1}}{m}(1-t)+\varrho_{2}t$ in (2.3), we obtain

$\begin{align} \frac{k}{\zeta}\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)&\leq\frac{1}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[h\left(\frac{1}{2^{\alpha}}\right)\int_{\psi^{-1}(\varrho_{1})}^{\psi^{-1}(m\varrho_{2})}\frac{\varphi(\psi(u))}{e^{\eta\psi(u)}}\left(m\varrho_{2}-\psi(u)\right)^{\frac{\zeta}{k}-1}d(\psi(u))\\&+mH\left(\frac{1}{2}\right)\int_{\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)}^{\psi^{-1}(\varrho_{2})}\frac{\varphi(\psi(v))}{e^{\eta\psi(v)}}\left(\psi(v)-\frac{\varrho_{1}}{m}\right)^{\frac{\zeta}{k}-1}d(\psi(v))\bigg]. \end{align}$

(2.4)

Further, taking the maximum value of exponential function and using Definition 4, we get

$\begin{align} \varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)&\leq \frac{\Gamma_{k}({\zeta+k})}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+g_{2}(\eta)m^{\frac{\zeta}{k}+1}H\left(\frac{1}{2}\right) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\!\bigg]. \end{align}$

Again using exponentially $(\alpha, h-m)$ -convexity of $\varphi$ , for $t\in[0, 1]$ , we have

$\begin{align} &g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\varphi(\varrho_{1}t+m(1-t)\varrho_{2})+mg_{2}(\eta)H\left(\frac{1}{2}\right)\varphi\left(\frac{\varrho_{1}}{m}(1-t)+\varrho_{2}t\right)\\&\leq h(t^{\alpha})\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\\&+mH(t)\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]. \end{align}$

(2.5)

By integrating (2.5) over the interval $[0, 1]$ after multiplying with $t^{{\frac{\zeta}{k}-1}}$ , we get

$\begin{align} &g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\int_{0}^{1}\varphi(t\varrho_{1}+m(1-t)\varrho_{2})t^{{\frac{\zeta}{k}-1}}dt+mg_{2}(\eta)H\left(\frac{1}{2}\right)\int_{0}^{1}\varphi\left(\frac{\varrho_{1}}{m}(1-t)+t\varrho_{2}\right)t^{{\frac{\zeta}{k}-1}}dt\\&\leq\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi(\varrho)}{e^{\eta \varrho_{2}}}\bigg]\int_{0}^{1}h(t^{\alpha})t^{{\frac{\zeta}{k}-1}}dt+m\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\\&+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]\int_{0}^{1}t^{{\frac{\zeta}{k}-1}}H(t)dt. \end{align}$

(2.6)

Again using substitutions as considered in (2.3), the inequality (2.6) leads to the second inequality of (2.1).

The following remark states the connection of Theorem 7 with already established results.

Remark 2. (i) If we substitute $\eta = 0$ , $\alpha = 1$ and $\psi(t) = t$ in (2.1), then [32,Theorem 2.1] can be obtained.

(ii) If we substitute $k = m = \alpha = 1$ , $\eta = 0$ and $h(t) = \psi(t) = t$ in (2.1), then Theorem 1 can be obtained.

(iii) If we substitute $\eta = 0$ , $h(t) = \psi(t) = t$ and $m = \alpha = 1$ in (2.1), then refinement of Theorem 1 can be obtained.

(iv) If we substitute $\alpha = k = \zeta = m = 1$ , $\eta = 0$ and $h(t) = \psi(t) = t$ in (2.1), then Hadamard inequality can be obtained.

(v) If we substitute $\eta = 0$ , $m = \alpha = 1$ and $h(t) = t$ in (2.1), then [28,Theorem 1] can be obtained.

(vi) If we substitute $\eta = 0$ , $k = m = \alpha = 1$ and $h(t) = t$ in (2.1), then [37,Theorem 2.1] can be obtained.

(vii) If we substitute $\alpha = k = 1$ , $h(t) = \psi(t) = t$ and $\eta = 0$ in (2.1), then [34,Theorem 2.1] can be obtained.

(viii) If we substitute $\alpha = 1$ , $h(t) = t^{s}$ and $\psi(t) = t$ in (2.1), then [39,Theorem 2] can be obtained.

(ix) If we substitute $\alpha = 1$ , $\eta = 0$ and $h(t) = t^{s}$ in (2.1), then [38,Corollary 1] can be obtained.

(x) If we substitute $\eta = 0$ and $k = 1$ in (2.1), then [31,Corollary 1] can be obtained.

(xi) If we substitute $\eta = 0$ and $\alpha = 1$ in (2.1), then [31,Corollary 1] gives the refinement of resulting inequality.

In the following we give inequality (2.1) for exponentially $(h-m)$ -convex, exponentially $(s, m)$ -convex, exponentially $s$ -convex, exponentially $m$ -convex and exponentially convex functions.

Corollary 1. If we take $\alpha = 1$ in (2.1), then the following inequality holds for exponentially $(h-m)$ -convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq \frac{h\left(\frac{1}{2}\right)\Gamma_{k}({\zeta+k})}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))+g_{2}(\eta)m^{\frac{\zeta}{k}+1}\\&\times \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)\left( \psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\!\bigg]\leq\frac{\zeta h\left(\frac{1}{2}\right)}{k}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\\&\times\int_{0}^{1}h(t)t^{{\frac{\zeta}{k}-1}}dt+\frac{m\zeta h\left(\frac{1}{2}\right)}{k}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta\varrho_{1}}{m^{2}}}}\bigg]\int_{0}^{1}t^{{\frac{\zeta}{k}-1}}h(1-t)dt. \end{align}$

Corollary 2. If we take $\alpha = 1$ and $h(t) = t^{s}$ in (2.1), then the following inequality holds for exponentially $(s, m)$ -convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq \frac{\Gamma_{k}({\zeta+k})}{2^{s}(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))+m^{\frac{\zeta}{k}+1}g_{2}(\eta)\\&\times \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)\left( \psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\leq\frac{\zeta}{2^{s}(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{2}}}\bigg]\\&+\frac{m\mu B\left(1+s, \frac{\mu}{k}\right)}{2^{s}k}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]. \end{align}$

If we put $m = 1$ in the above inequality, then the result of exponentially $s$ -convex function can be obtained.

Corollary 3. If we take $\alpha = 1$ and $h(t) = t$ in (2.1), then the following inequality holds for exponentially $m$ -convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq \frac{\Gamma_{k}({\zeta+k})}{2(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))+g_{2}(\eta)m^{\frac{\zeta}{k}+1}\\&\times \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)\left( \psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\leq\frac{\zeta}{2(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\\&+\frac{m}{2(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]. \end{align}$

Corollary 4. If we take $\alpha = m = 1$ and $h(t) = t$ in (2.1), then the following inequality holds for exponentially convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq\frac{\Gamma_{k}({\zeta+k})}{2(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\\\times&\left[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))+g_{2}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\right]\\&\leq\frac{\zeta}{2(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+g_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]+\frac{1}{2(\zeta+k)}\left[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+g_{2}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}\right]. \end{align}$

The next theorem is another version of the Hadamard inequality for exponentially $(\alpha, h-m)$ -convex functions.

Theorem 8. Under the assumptions of Theorem 7, the following $k$ -fractional integral inequality holds:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}}\Gamma_{k}(\zeta+k)}{^{}(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right) \quad _{k}^{\psi}I_{\psi^{-1}(\frac{\varrho_{1}+m\varrho_{2}}{2})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+g_{2}(\eta)H\left(\frac{1}{2}\right)m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}(\frac{\varrho_{1}+m\varrho_{2}}{2m})^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\leq\frac{\zeta}{k}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}\\&+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{{\frac{\zeta}{k}-1}}dt+\frac{\zeta m}{k}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\\&+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]\int_{0}^{1}H\left(\frac{t}{2}\right)t^{{\frac{\zeta}{k}-1}}dt, \end{align}$

(2.7)

where $\zeta > 0$ , $H(t) = h(1-t^{\alpha})$ and

$\begin{equation*} g_{1}(\eta) = \begin{cases} {}{e^{-\eta m\varrho_{2}}} & \mathit{\text{if}} \ \eta < 0 \\ {}{e^{-\eta\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)}} & \mathit{\text{if}} \ \eta > 0 \end{cases}, \quad g_{2}(\eta) = \begin{cases} {}{e^{-\eta\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)}} & \mathit{\text{if}} \ \eta < 0 \\ {}{e^{\frac{-\eta \varrho_{1}}{m}}} & \mathit{\text{if}} \ \eta > 0 \end{cases} . \end{equation*}$

Proof. By setting $x = \frac{\varrho_{1}t}{2}+m(\frac{2-t}{2})\varrho_{2}$ , $y = \frac{\varrho_{1}}{m}(\frac{2-t}{2})+\frac{\varrho_{2}t}{2}$ , $t\in[0, 1]$ , in (2.2) and integrating the resulting inequality over $[0, 1]$ after multiplying with $t^{{\frac{\zeta}{k}-1}}$ , we get

$\begin{align} &\frac{k}{\zeta}\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq h\left(\frac{1}{2^{\alpha}}\right)\int_{0}^{1}\frac{\varphi\left(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\right)}{e^{\eta\left(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\right)}}t^{{\frac{\zeta}{k}-1}}dt\\&+{m}H\left(\frac{1}{2}\right)\int_{0}^{1}\frac{\varphi\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)}{e^{\eta\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)}}t^{{\frac{\zeta}{k}-1}}dt. \end{align}$

(2.8)

By setting $\psi(u) = \frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}$ and $\psi(v) = \frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}$ in (2.8), we obtain

$\begin{align} &\frac{k}{\zeta}\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}}}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\\\times&\bigg[h\left(\frac{1}{2^{\alpha}}\right)\int_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)}^{\psi^{-1}(m\varrho_{2})}\frac{\varphi(\psi(u))}{e^{\eta\psi(u)}}\left({{{m\varrho_{2}-\psi(u)}}}\right)^{\frac{\zeta}{k}-1}d(\psi(u))\\&+m^{\frac{\zeta}{k}+1}H\left(\frac{1}{2}\right)\int_{\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)}^{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)}\frac{\varphi(\psi(v))}{e^{\eta\psi(v)}}\left({{\psi(v)-\frac{\varrho_{1}}{m}}}\right)^{\frac{\zeta}{k}-1}d(\psi(v))\bigg]. \end{align}$

(2.9)

Further, taking the maximum value of exponential function and using Definition 4, we get

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}}\Gamma_{k}(\zeta+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right) \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+g_{2}(\eta)h\left(\frac{2^{\alpha}-1}{2^{\alpha}}\right)m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]. \end{align}$

Again using exponentially $(\alpha, h-m)$ -convexity of $\varphi$ , for $t\in[0, 1]$ , we have

$\begin{align} &g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\varphi\left(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\right)+mg_{2}(\eta)H\left(\frac{1}{2}\right)\varphi\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)\\&\leq h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mH\left(\frac{1}{2}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]+mH\left(\frac{t}{2}\right)\\&\times\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]. \end{align}$

(2.10)

By integrating (2.10) over $[0, 1]$ after multiplying with $t^{{\frac{\zeta}{k}-1}}$ , the following inequality holds

$\begin{align} &g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\int_{0}^{1}\varphi\left(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\right)t^{{\frac{\zeta}{k}-1}}dt+mg_{2}(\eta)H\left(\frac{1}{2}\right)\\&\times\int_{0}^{1}\varphi\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)t^{{\frac{\zeta}{k}-1}}dt\leq \left[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\right]\\&\times\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{{\frac{\zeta}{k}-1}}dt+m\bigg[g_{1}(\eta)h\left(\frac{1}{2^{\alpha}}\right)\frac{\varphi(\varrho_{2})}{e^{\eta\varrho_{2}}}+mg_{2}(\eta)H\left(\frac{1}{2}\right)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]\int_{0}^{1}h\left(\frac{2^{\alpha}-t^{\alpha}}{2^{\alpha}}\right)t^{{\frac{\zeta}{k}-1}}dt. \end{align}$

(2.11)

Again using substitutions as considered in (2.8), the second inequality of (2.7) can be obtained.

The following remark states the connection of Theorem 8 with already established results.

Remark 3. (i) If we substitute $\eta = 0$ and $k = 1$ in (2.7), then [31,Corollary 3] can be obtained.

(ii) If we substitute $\eta = 0$ and $\alpha = 1$ in (2.7), then [31,Theorem 10] gives the refinement of resulting inequality.

(iii) If we take $h(t) = \psi(t) = t$ , $m = k = \alpha = 1$ and $\eta = 0$ (2.7), then Theorem 2 can be obtained.

(iv) If we substitute $h(t) = \psi(t) = t$ , $m = \alpha = 1$ , $\eta = 0$ in (2.7), then refinement of Theorem 2 can be obtained.

(v) If we use $h(t) = \psi(t) = t$ , $m = \zeta = k = \alpha = 1$ , $\eta = 0$ and in (2.7), then the Hadamard inequality can be obtained.

(vi) If we substitute $h(t) = t, m = \alpha = 1$ and $\eta = 0$ in (2.7), then [35,Corrollary 3] can be obtained.

(vii) If we substitute $h(t) = \psi(t = )t, k = \alpha = 1$ and $\eta = 0$ in (2.7), then [33,Theorem 2.1] can be obtained.

(viii) If we substitute $\alpha = 1$ , $h(t) = t^{s}$ and $\eta = 0$ in (2.7), then [38,Corollary 3] can be obtained.

(ix) If we substitute $h(t) = t$ , $m = \alpha = k = 1$ and $\eta = 0$ in (2.7), then [40,Corrollary 3] can be obtained.

In the following we give inequality (2.7) for exponentially $(h-m)$ -convex, exponentially $(s, m)$ -convex, exponentially $s$ -convex, exponentially $m$ -convex and exponentially convex functions.

Corollary 5. If we take $\alpha = 1$ in (2.7), then the following inequality holds for exponentially $(h-m)$ -convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}}h\left(\frac{1}{2}\right)\Gamma_{k}(\zeta+k)}{^{}(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+g_{2}(\eta)m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\\&\leq\frac{\zeta h\left(\frac{1}{2}\right)}{k}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\int_{0}^{1}h\left(\frac{t}{2}\right)t^{{\frac{\zeta}{k}-1}}dt+\frac{\zeta mh\left(\frac{1}{2}\right)}{k}\\&\times\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]\int_{0}^{1}h\left(\frac{2-t}{2}\right)t^{{\frac{\zeta}{k}-1}}dt. \end{align}$

Corollary 6. If we take $\alpha = 1$ and $h(t) = t^{s}$ in (2.7), then the following inequality holds for exponentially $(s, m)$ -convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}-s}\Gamma_{k}(\zeta+k)}{^{}(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+g_{2}(\eta)m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2} }{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\leq\frac{\zeta}{2^{2s}(\zeta+sk)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}\\&+mg_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]+\frac{\zeta mB\left(1+s, \frac{\zeta}{k}\right)}{2^{2s}k}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]. \end{align}$

If we put $m = 1$ in the above inequality, then the result of exponentially $s$ -convex function can be obtained.

Corollary 7. If we take $\alpha = 1$ , $h(t) = t$ in (2.7), then the following inequality holds for exponentially $m$ -convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}(\zeta+k)}{^{}(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)^+}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(m\varrho_{2}\right)\right)+g_{2}(\eta)m^{\frac{\zeta}{k}+1}\\&\times \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]\leq\frac{\zeta}{4(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+mg_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\\&+\frac{m(\zeta+2k)}{4(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+mg_{2}(\eta)\frac{\varphi\left(\frac{\varrho_{1}}{m^{2}}\right)}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\bigg]. \end{align}$

Corollary 8. If we take $\alpha = m = 1$ , $h(t) = t$ in (2.7), then the following inequality holds for exponentially convex functions:

$\begin{align} &\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\leq\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}(\zeta+k)}{(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[g_{1}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))\\&+g_{2}(\eta) \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}({\varrho_{1}}))\bigg]\leq\frac{\zeta}{4(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}+g_{2}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}\bigg]\\&+\frac{(\zeta+2k)}{4(\zeta+k)}\bigg[g_{1}(\eta)\frac{\varphi(\varrho_{2})}{e^{\eta \varrho_{2}}}+g_{2}(\eta)\frac{\varphi(\varrho_{1})}{e^{\eta \varrho_{1}}}\bigg]. \end{align}$

3. Error estimations of Hadamard inequalities for exponentially $(\alpha, h-m)$ -convex functions

In this section we give error estimations of the Hadamard inequalities by using exponentially $(\alpha, h-m)$ -convex functions via generalized Riemann-Liouville fractional integrals. The following identity is useful to prove the next theorem.

Lemma 1. ^[28] Let $\varrho_{1} < \varrho_{2}$ and $\varphi:[\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ . Also, suppose that $\varphi'\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Then, for $k > 0$ , the following identity holds for the operators given in (1.7) and (1.8):

$\begin{align} &\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma_{k}({\zeta+k})}{2(\varphi_{2}-\varphi_{1})^\frac{\zeta}{k}}\left[_{k}^{\psi}I_{\psi^{-1}(\varphi_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varphi_{2}))+\!_{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^{-}}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\right]\\& = \frac{\varrho_{2}-\varrho_{1}}{2}\int_{0}^{1}\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)\varphi'\left(t\varrho_{1}+(1-t)\varrho_{2}\right)dt. \end{align}$

(3.1)

Theorem 9. Let $\varphi: [\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ such that $\varphi'\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Also suppose that $|\varphi^\prime|$ is exponentially $(\alpha, h-m)$ -convex on $[\varrho_{1}, \varrho_{2}]$ . Then, for $k > 0$ , $\eta\in\mathbb{R}$ and $(\alpha, m)\in(0, 1]^{2}$ , the following $k$ -fractional integral inequality holds for the operators given in (1.7) and (1.8):

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma_{k}({\zeta}+k)}{2(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\left[_{k}^{\psi}I_{\psi^{-1}({\varrho_{1}})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))+\!_{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2}\bigg[\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}\bigg(\int_{0}^{\frac{1}{2}}h(t^{\alpha})\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)dt+\int_{\frac{1}{2}}^{1}h(t^{\alpha})\left(t^{\frac{\zeta}{k}}-(1-t)^{\frac{\zeta}{k}}\right)dt\bigg)\\ &+\frac{m\left|\varphi'\left(\frac{\varrho_{2}}{m}\right)\right|}{e^{\frac{\eta \varrho_{2}}{m}}}\bigg(\int_{0}^{\frac{1}{2}}H(t)\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)dt+\int_{\frac{1}{2}}^{1}H(t)\left(t^{\frac{\zeta}{k}}-(1-t)^{\frac{\zeta}{k}}\right)dt\bigg)\bigg], \end{align}$

(3.2)

where $H(t)$ is defined in Theorem 7.

Proof. From Lemma 1, it follows that

(3.3)

By using exponentially $(\alpha, h-m)$ -convexity of $|\varphi'|$ , for $t\in[0, 1]$ , we have

$\begin{align} &|\varphi'(t\varrho_{1}+(1-t)\varrho_{2})|\leq h(t^{\alpha})\frac{|\varphi'(\varrho_{1})|}{e^{\eta \varrho_{1}}}+mH(t)\frac{\left|\varphi'\left(\frac{\varrho_{2}}{m}\right)\right|}{e^{\frac{\eta \varrho_{2}}{m}}}. \end{align}$

(3.4)

Using (3.4) in (3.3), we get

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma_{k}({\zeta+k})}{2(\varphi_{2}-\varphi_{1})^\frac{\zeta}{k}}\left[_{k}^{\psi}I_{\psi^{-1}(\varphi_{1})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varphi_{2}))+\!_{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^{-}}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2}\int_{0}^{1}\left|(1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right|\bigg[h(t^{\alpha})\frac{|\varphi'(\varrho_{1})|}{e^{\eta \varrho_{1}}}+mH(t)\frac{\left|\varphi'\left(\frac{\varrho_{2}}{m}\right)\right|}{e^{\frac{\eta \varrho_{2}}{m}}}\bigg] \\& = \frac{\varrho_{2}-\varrho_{1}}{2}\bigg[\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}\left[\int_{0}^{\frac{1}{2}}h(t^{\alpha})\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)dt+\int_{\frac{1}{2}}^{1}h(t^{\alpha})\left(t^{\frac{\zeta}{k}}-(1-t)^{\frac{\zeta}{k}}\right)dt\right]\\&+\frac{m\left|\varphi'\left(\frac{\varrho_{2}}{m}\right)\right|}{e^{\frac{\eta \varrho_{2}}{m}}}\bigg[\int_{0}^{\frac{1}{2}}H(t)\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)dt+\int_{\frac{1}{2}}^{1}H(t)\left(t^{\frac{\zeta}{k}}-(1-t)^{\frac{\zeta}{k}}\right)dt\bigg]. \end{align}$

The following remark states the connection of Theorem 9 with already established results.

Remark 4. (i) If we substitute $\eta = 0$ and $k = 1$ in (3.2), then [31,Corllary 7] can be obtained.

(ii) If we substitute $\eta = 0$ and $\alpha = 1$ in (3.2), then [31,Theorem 11] gives the refinement of resulting inequality.

(iii) If we substitute $h(t) = t$ , $m = \alpha = 1$ and $\eta = 0$ in (3.2), then [35,Corollary 10] can be obtained.

(iv) If we substitute $m = \alpha = 1$ , $\eta = 0$ and $h(t) = t^{s}$ in (3.2), then [28,Theorem 2] can be obtained.

(v) If we substitute $m = \alpha = 1$ , $h(t) = \psi(t) = t$ and $\eta = 0$ in (3.2), then [26,Theorem 2.4] can be obtained.

(vi) If we substitute $k = m = \alpha = 1$ , $h(t) = \psi(t) = t$ and $\eta = 0$ in (3.2), then Theorem 3 can be obtained.

(vii) If we substitute $k = \alpha = \zeta = m = 1$ , $h(t) = \psi(t) = t$ and $\eta = 0$ in (3.2), then [29,Theorem 2.2] can be obtained.

(viii) If we substitute $\alpha = 1$ , $\eta = 0$ and $h(t) = t^{s}$ in (3.2), then [38,Corollary 5] can be obtained.

In the following we present the inequality (3.2) for exponentially $(h-m)$ -convex, exponentially $(s, m)$ -convex, exponentially $s$ -convex, exponentially $m$ -convex and exponentially convex functions.

Corollary 9. If we take $\alpha = 1$ in (3.2), then the following inequality holds for exponentially $(h-m)$ -convex functions:

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma_{k}({\zeta}+k)}{2(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\left[_{k}^{\psi}I_{\psi^{-1}({\varrho_{1}})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))+\!_{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2}\bigg[\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}\bigg(\int_{0}^{\frac{1}{2}}h(t)\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)dt+\int_{\frac{1}{2}}^{1}h(t)\left(t^{\frac{\zeta}{k}}-(1-t)^{\frac{\zeta}{k}}\right)dt\bigg)\\ &+\frac{m\left|\varphi'\left(\frac{\varrho_{2}}{m}\right)\right|}{e^{\frac{\eta \varrho_{2}}{m}}}\bigg(\int_{0}^{\frac{1}{2}}h(1-t)\left((1-t)^{\frac{\zeta}{k}}-t^{\frac{\zeta}{k}}\right)dt+\int_{\frac{1}{2}}^{1}h(1-t)\left(t^{\frac{\zeta}{k}}-(1-t)^{\frac{\zeta}{k}}\right)dt\bigg)\bigg]. \end{align}$

Corollary 10. If we take $\alpha = 1$ and $h(t) = t^{s}$ in (3.2), then the following inequality holds for exponentially $(s, m)$ -convex functions:

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma_{k}({\zeta}+k)}{2(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\left[_{k}^{\psi}I_{\psi^{-1}({\varrho_{1}})^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))+\!_{k}^{\psi}I_{\psi^{-1}(\varrho_{2})^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2}\bigg[\frac{|\varphi'(\varrho_{1})|}{e^{\eta \varrho_{1}}}\bigg(2B\left(\frac{1}{2};s+1, \frac{\zeta}{k}+1\right)+\frac{1-\left(\frac{1}{2}\right)^{s+\frac{\zeta}{k}}}{s+\frac{\zeta}{k}+1}-B\left(1+s, 1+\frac{\zeta}{k}\right)\bigg)\\&+\frac{m\bigg|\varphi'\left(\frac{\varrho_{2}}{m}\right)\bigg|}{e^{\frac{\eta \varrho_{2}}{m}}}\bigg(\frac{1-\left(\frac{1}{2}\right)^{s+\frac{\zeta}{k}+1}}{s+\frac{\zeta}{k}+1}-\frac{_{2}F_{1}\!\left(-s, 1+\frac{\zeta}{k}, 2+\frac{\zeta}{k};\frac{1}{2}\right)}{{}{2}^{1+\frac{\zeta}{k}}\left(\frac{\zeta}{k}+1\right)}+B\left(1+s, 1+\frac{\zeta}{k}\right)\\&-\frac{k(k+\zeta+2^{s}(k+ks+\zeta) \quad _{2}F_{1}\!\left(-s, 1+\frac{\zeta}{k}, 2+\frac{\zeta}{k};\frac{1}{2}\right)}{2^{s+\frac{\zeta}{k}+1}(sk+{\zeta}+k)(\zeta+k)}\bigg)\bigg]. \end{align}$

If we put $m = 1$ in the above inequality, then the result of exponentially $s$ -convex function can be obtained.

Corollary 11. If we take $\alpha = m = 1$ and $h(t) = t$ in (3.2), then the following inequality holds for exponentially convex functions:

Corollary 12. If we take $\alpha = m = k = 1$ and $h(t) = \psi(t) = t$ in (3.2), then the following inequality holds for exponentially convex functions via Riemann-Liouville fractional integrals:

$\begin{align} &\left|\frac{\varphi(\varrho_{1})+\varphi(\varrho_{2})}{2}-\frac{\Gamma({\zeta}+1)}{2(\varrho_{2}-\varrho_{1})^{{\zeta}}}\left[_{}^{}I_{({\varrho_{1}})^+}^{\zeta}\varphi(\varrho_{2})+_{}^{}I_{(\varrho_{2})^-}^{\zeta}\varphi(\varrho_{1})\right]\right|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{2(\frac{\zeta}{k}+1)} \left(1-\frac{1}{2^{\frac{\zeta}{k}}}\right)\left(\frac{|\varphi'(\varrho_{1})|}{e^{\eta\varrho_{1}}}+\frac{|\varphi^\prime(\varrho_{2})|}{e^{\eta\varrho_{2}}}\right). \end{align}$

The following identity will be useful to obtain the next results.

Lemma 2. ^[38] Let $\varphi:[\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ such that $\varphi\in L_{1}[\varrho_{1}, \varrho_{2}]$ . Then for $k > 0$ and $m\in(0, 1]$ , the following integral identity holds for operators given in (1.7) and (1.8):

$\begin{align} &\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\\& = \frac{m\varrho_{2}-\varrho_{1}}{4}\bigg[\int_{0}^{1}t^{\frac{\zeta}{k}}\varphi'\left(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\right)dt-\int_{0}^{1}t^{\frac{\zeta}{k}}\varphi'\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)dt\bigg]. \end{align}$

(3.5)

Theorem 10. Let $\varphi: [\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ such that $\varphi'\in\text{Ł}_{1}[\varrho_{1}, \varrho_{2}]$ . Also suppose that $|\varphi'|^{q}$ is exponentially $(\alpha, h-m)$ -convex function on $[\varrho_{1}, \varrho_{2}]$ for $q\geq1$ . Then, for $\eta\in\mathbb{R}$ , $k > 0$ and $(\alpha, m)\in(0, 1]^{2}$ , the following fractional integral inequality holds for operators given in (1.7) and (1.8):

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4\left(\frac{\zeta}{k}+1\right)^{1-\frac{1}{q}}}\bigg[\bigg(\frac{{|\varphi'(\varrho_{1})|^{q}}}{e^{\eta \varrho_{1}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{\frac{\zeta}{k}}dt+\frac{{m|\varphi'(\varrho_{2})|^{q}}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{2^{\alpha}-t^{\alpha}}{2^{\alpha}}\right)t^{\frac{\zeta}{k}}dt\bigg)^{\frac{1}{q}}\\&+\bigg(\frac{{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}}{e^{{\frac{\eta \varrho_{1}}{m^{2}}}}}\int_{0}^{1}H\left(\frac{t}{2}\right)t^{\frac{\zeta}{k}}dt+\frac{{|\varphi'(\varrho_{2})|^{q}}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{\frac{\zeta}{k}}dt\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

(3.6)

Proof. We divide the proof in two cases:

Case 1. For $q = 1$ . Applying Lemma 2 and using exponentially $(\alpha, h-m)$ -convexity of $|\varphi'|$ , we have

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4}\bigg[\int_{0}^{1}\bigg|t^{\frac{\zeta}{k}}\varphi'\left(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\right)\bigg|dt+\int_{0}^{1}\bigg|t^{\frac{\zeta}{k}}\varphi'\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)\bigg|dt\bigg] \\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4}\bigg[\left(\frac{|\varphi'(\varrho_{1})|}{e^{\eta \varrho_{1}}}+\frac{|\varphi'(\varrho_{2})|}{e^{\eta \varrho_{2}}}\right)\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{\frac{\zeta}{k}}dt+m\left(\frac{|\varphi'(\varrho_{2})|}{e^{\eta \varrho_{2}}}+\frac{\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\right)\\&\times\int_{0}^{1}H\left(\frac{t}{2}\right)t^{\frac{\zeta}{k}}dt\bigg]. \end{align}$

Case 2. Now for $q > 1$ . From Lemma 2 and using power mean inequality, we get

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4}\left(\int_{0}^{1}t^{\frac{\zeta}{k}}dt\right)^{1-\frac{1}{q}}\bigg[\bigg(\int_{0}^{1}t^{\frac{\zeta}{k}}\bigg|\varphi'\bigg(\frac{\varrho_{1}t}{2}+m\left(\frac{2-t}{2}\right)\varrho_{2}\bigg)\bigg|^{q}dt\bigg)^{\frac{1}{q}}\\&+\bigg(\int_{0}^{1}t^{\frac{\zeta}{k}}\bigg|\varphi'\left(\frac{\varrho_{1}}{m}\left(\frac{2-t}{2}\right)+\frac{\varrho_{2}t}{2}\right)\bigg|^{q}dt\bigg)^{\frac{1}{q}}\bigg]\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4\left(\frac{\zeta}{k}+1\right)^{1-\frac{1}{q}}}\bigg[\bigg(\frac{{|\varphi'(\varrho_{1})|^{q}}}{e^{\eta \varrho_{1}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{\frac{\zeta}{k}}dt+\frac{{m|\varphi'(\varrho_{2})|^{q}}}{e^{\eta \varrho_{2}}}\int_{0}^{1}H\left(\frac{t}{2}\right)t^{\frac{\zeta}{k}}dt\bigg)^{\frac{1}{q}}\\&+\bigg(\frac{{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}}{e^{{\frac{\eta \varrho_{1}}{m^{2}}}}}\int_{0}^{1}H\left(\frac{t}{2}\right)t^{\frac{\zeta}{k}}dt+\frac{{|\varphi'(\varrho)_{2}|^{q}}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)t^{\frac{\zeta}{k}}dt\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

Hence (3.6) is obtained.

The following remark states the connection of Theorem 10 with already established results.

Remark 5. (i) If we substitute $\eta = 0$ , $\alpha = 1$ and $h(t) = t^{s}$ in (3.6), then [38,Corollary 7] can be obtained.

(ii) If we substitute $h(t) = \psi(t) = t$ , $k = \alpha = 1$ and $\eta = 0$ in (3.6), then [33,Theorem 2.4] can be obtained.

(iii) If we substitute $\eta = 0$ , $h(t) = \psi(t) = t$ and $\alpha = m = 1$ in (3.6), then [27,Theorem 3.1] can be obtained.

(iv) If we substitute $h(t) = \psi(t) = t$ , $m = k = \alpha = 1$ and $\eta = 0$ in (3.6), then [25,Theorem 5] can be obtained.

(v) If we substitute $q = m = k = \zeta = \alpha = 1$ , $h(t) = \psi(t) = t$ and $\eta = 0$ in (3.6), then [36,Theorem 2.2] can be obtained.

(vi) If we substitute $\eta = 0$ , $m = \alpha = 1$ and $h(t) = t$ in (3.6), then [35,Corollary 10] can be obtained.

(vii) If we substitute $\eta = 0$ and $k = 1$ in (3.6), then [31,Corollary 10] can be obtained.

(viii) If we substitute $\eta = 0$ and $\alpha = 1$ in (3.6), then [31,Theorem 12] gives the refinement of resulting inequality.

In the following we present the inequality (3.6) for exponentially $(h-m)$ -convex, exponentially $(s, m)$ -convex, exponentially $s$ -convex, exponentially $m$ -convex and exponentially convex functions.

Corollary 13. If we take $\alpha = 1$ in (3.6), then the following inequality holds for exponentially $(h-m)$ -convex functions:

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4\left(\frac{\zeta}{k}+1\right)^{1-\frac{1}{q}}}\bigg[\bigg(\frac{{|\varphi'(\varrho_{1})|^{q}}}{e^{\eta \varrho_{1}}}\int_{0}^{1}h\left(\frac{t}{2}\right)t^{\frac{\zeta}{k}}dt+\frac{{m|\varphi'(\varrho_{2})|^{q}}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{2-t}{2}\right)t^{\frac{\zeta}{k}}dt\bigg)^{\frac{1}{q}}\\&+\bigg(\frac{{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}}{e^{{\frac{\eta \varrho_{1}}{m^{2}}}}}\int_{0}^{1}h\left(\frac{2-t}{2}\right)t^{\frac{\zeta}{k}}dt+\frac{{|\varphi'(\varrho_{2})|^{q}}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{t}{2}\right)t^{\frac{\zeta}{k}}dt\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

Corollary 14. If we take $\alpha = 1$ and $h(t) = t^{s}$ in (3.6), then the following inequality holds for exponentially $(s, m)$ -convex functions:

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4(\frac{\zeta}{k}+1)\left(2^{s}(\frac{\zeta}{k}+s+1)\right)^{\frac{1}{q}}}\bigg[\bigg(\left(\frac{\zeta}{k}+1\right)\frac{\left|\varphi'(\varrho_{1})\right|^{q}}{e^{\eta \varrho_{1}}}\\&+2^{s}m\left(\frac{\zeta}{k}+s+1\right) \quad _{2}F_{1}\left(-s, 1+\frac{\zeta}{k}, 2+\frac{\zeta}{k};\frac{1}{2}\right)\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\bigg)^{\frac{1}{q}}\\&+\bigg(2^{s}m\; \quad _{2}F_{1}\!\left(-s, 1+\frac{\zeta}{k}, 2+\frac{\zeta}{k};\frac{1}{2}\right)\left(\frac{\zeta}{k}+s+1\right)\frac{{\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}}{e^{{\frac{\eta \varrho_{1}}{m^{2}}}}}+\left(\frac{\zeta}{k}+1\right)\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

If we put $m = 1$ in the above inequality, then the result of exponentially $s$ -convex function can be obtained.

Corollary 15. If we take $\alpha = m = 1$ and $h(t) = t$ in (3.6), then the following inequality holds for exponentially convex functions:

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))+ \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{1}))\bigg]\\&-\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\bigg|\leq\frac{\varrho_{2}-\varrho_{1}}{4\left(\frac{\zeta}{k}+1\right)\left(2(\frac{\zeta}{k}+2)\right)^{\frac{1}{q}}}\bigg[\bigg(\left(\frac{\zeta}{k}+1\right)\frac{\left|\varphi'(\varrho_{1})\right|^{q}}{e^{\eta \varrho_{1}}}+\left(\frac{\zeta}{k}+3\right)\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\bigg)^{\frac{1}{q}}\\&+\bigg(\left(\frac{\zeta}{k}+3\right)\frac{\left|\varphi'(\varrho_{1}))\right|^{q}}{e^{\eta \varrho_{1}}}+\left(\frac{\zeta}{k}+1\right)\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

Corollary 16. If we take $\alpha = k = m = q = \zeta = 1$ , $h(t) = \psi(t) = t$ in (3.6), then the following inequality is obtained:

$\begin{align} &\bigg|\frac{1}{(\varrho_{2}-\varrho_{1})}\int_{0}^{1}\varphi(\nu)d\nu-\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\bigg|\leq\frac{\varrho_{2}-\varrho_{1}}{8}\bigg[\frac{{|\varphi'(\varrho_{1})|}}{e^{\eta \varrho_{1}}}+\frac{{|\varphi'(\varrho_{2})|}}{e^{\eta \varrho_{2}}}\bigg]. \end{align}$

Theorem 11. Let $\varphi:[\varrho_{1}, \varrho_{2}]\rightarrow \mathbb{R}$ be a differentiable mapping on $(\varrho_{1}, \varrho_{2})$ with $0\leq \varrho_{1} < m\varrho_{2}$ . Also suppose that $|\varphi'|^{q}$ is exponentially $(\alpha, h-m)$ -convex function on $[\varrho_{1}, \varrho_{2}]$ for $q > 1$ . Then, for $k > 0$ and $(\alpha, m)\in(0, 1]^{2}$ , the following fractional integral inequality holds for the operators given in (1.7) and (1.8):

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4\left(\frac{{\zeta}p}{k}+1\right)^{\frac{1}{p}}}\bigg[\bigg(\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}^{q}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)dt+\frac{m\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{2^{\alpha}-t^{\alpha}}{2^{\alpha}}\right)dt\bigg)^{\frac{1}{q}}\\&+\Bigg(\frac{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\int_{0}^{1}H\left(\frac{t}{2}\right)dt+\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)dt\bigg)^{\frac{1}{q}}\Bigg], \end{align}$

(3.7)

with $\frac{1}{p}+\frac{1}{q} = 1$ .

Proof. By applying Lemma 2 and using the property of modulus, we get

Now applying Hölder's inequality for integrals, we get

Using exponentially $(\alpha, h-m)$ -convexity of $\left|\varphi'\right|^{q}$ , we get

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4\left(\frac{{\zeta}p}{k}+1\right)^{\frac{1}{p}}}\bigg[\bigg({\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}^{q}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)dt+{\frac{m\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}}\int_{0}^{1}h\left(\frac{2^{\alpha}-t^{\alpha}}{2^{\alpha}}\right)dt\bigg)^{\frac{1}{q}}\\&+\bigg({\frac{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}}\int_{0}^{1}h\left(\frac{2^{\alpha}-t^{\alpha}}{2^{\alpha}}\right)dt+{\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)dt\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

The following remark is the connection of Theorem 3.3 with already established results.

Remark 6. (i) If we substitute $\eta = 0$ and $k = 1$ in (3.7), then [31,Corollary 12] can be obtained.

(ii) If we substitute $\eta = 0$ and $\alpha = 1$ in (3.7), then [31,Theorem 13] gives the refinement of resulting inequality.

(iii) If we substitute $h(t) = \psi(t) = t$ , $k = \alpha = 1$ and $\eta = 0$ in (3.7), then [33,Theorem 2.7] can be obtained.

(iv) If we substitute $\eta = 0$ , $h(t) = \psi(t) = t$ and $\alpha = m = 1$ in (3.7), then [27,Theorem 3.2] can be obtained.

(v) If we substitute $k = m = \zeta = \alpha = 1$ , $h(t) = \psi(t) = t$ and $\eta = 0$ in (3.7), then [36,Theorem 2.4] can be obtained.

(vi) If we substitute $\eta = 0$ , $\alpha = 1$ and $h(t) = t^{s}$ in (3.7), then [38,Corollary 9] can be obtained.

(vii) If we substitute $\alpha = m = 1$ , $h(t) = t$ and $\eta = 0$ in (3.7), then [35,Corollary 14] can be obtained.

In the following we give inequality (3.7) for exponentially $(h-m)$ -convex, exponentially $(s, m)$ -convex, exponentially $s$ -convex, exponentially $m$ -convex and exponentially convex functions.

Corollary 17. If we take $\alpha = 1$ in (3.7), then the following inequality holds for exponentially $(h-m)$ -convex functions:

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(m\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{\frac{\zeta}{k}+1} \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-\varrho_{1}}{4\left(\frac{{\zeta}p}{k}+1\right)^{\frac{1}{p}}}\bigg[\bigg(\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}^{q}\int_{0}^{1}h\left(\frac{t}{2}\right)dt+\frac{m\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{2-t}{2}\right)dt\bigg)^{\frac{1}{q}}\\&+\bigg(\frac{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\int_{0}^{1}h\left(\frac{2-t}{2}\right)dt+\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{t}{2}\right)dt\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

Corollary 18. If we take $\alpha = 1$ and $h(t) = t^{s}$ in (3.7), then the following inequality holds for exponentially $(s, m)$ -convex functions:

If we put $m = 1$ in the above inequality, then the result of exponentially $s$ -convex function can be obtained.

Corollary 19. If we take $\alpha = 1$ and $h(t) = t$ in (3.7), then the following inequality holds for exponentially $m$ -convex functions:

Corollary 20. If we take $\alpha = m = 1$ and $h(t) = t$ in (3.7), then the following inequality holds for exponentially convex functions:

$\begin{align} &\bigg|\frac{2^{\frac{\zeta}{k}-1}\Gamma_{k}({\zeta}+k)}{(\varrho_{2}-\varrho_{1})^{\frac{\zeta}{k}}}\bigg[ \quad _{k}^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(\varrho_{2}))+ \quad _{k}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)^-}^{\zeta}(\varphi\circ\psi)(\psi^{-1}({\varrho_{1}}))\bigg]-\varphi\left(\frac{\varrho_{1}+\varrho_{2}}{2}\right)\bigg|\\&\leq\frac{\varrho_{2}-\varrho_{1}}{16}\left(\frac{4}{{\frac{\alpha p}{k}}+1}\right)^\frac{1}{p}\bigg[\left(\frac{|\varphi'(\varrho_{1})|^{q}}{e^{\eta \varrho_{1}}}+\frac{3|\varphi'(\varrho_{2})|^{q}}{e^{\eta \varrho_{2}}}\right)^{\frac{1}{q}}+\left(\frac{3\left|\varphi'(\varrho_{1})\right|^{q}}{e^{\eta \varrho_{1}}}+\frac{|\varphi'(\varrho_{2})|^{q}}{e^{\eta \varrho_{2}}}\right)^{\frac{1}{q}}\bigg]. \end{align}$

In the following, we give inequality (3.7) for the operators given in (1.5) and (1.6).

Corollary 21. If we take $k = 1$ in (3.7), then the following inequality holds for exponentially convex functions:

$\begin{align} &\bigg|\frac{2^{{\zeta}{}-1}\Gamma({\zeta}+1)}{(m\varrho_{2}-\varrho_{1})^{\zeta}}\bigg[ \quad ^{\psi}I_{\psi^{-1}\left({\frac{\varrho_{1}+m\varrho_{2}}{2}}\right)^+}^{\zeta}(\varphi\circ\psi)(\psi^{-1}(m\varrho_{2}))\\&+m^{{\zeta}+1}\; _{}^{\psi}I_{\psi^{-1}\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)^-}^{\zeta}(\varphi\circ\psi)\left(\psi^{-1}\left(\frac{\varrho_{1}}{m}\right)\right)\bigg]-\frac{1}{2}\bigg[\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2}\right)+m\varphi\left(\frac{\varrho_{1}+m\varrho_{2}}{2m}\right)\bigg]\bigg|\\&\leq\frac{m\varrho_{2}-a}{4\left({{\zeta}p}{}+1\right)^{\frac{1}{p}}}\bigg[\bigg(\frac{\left|\varphi'(\varrho_{1})\right|}{e^{\eta \varrho_{1}}}^{q}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)dt+\frac{m\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{2^{\alpha}-t^{\alpha}}{2^{\alpha}}\right)dt\bigg)^{\frac{1}{q}}\\&+\bigg(\frac{m\left|\varphi'\left(\frac{\varrho_{1}}{m^{2}}\right)\right|^{q}}{e^{\frac{\eta \varrho_{1}}{m^{2}}}}\int_{0}^{1}H\left(\frac{t}{2}\right)dt+\frac{\left|\varphi'(\varrho_{2})\right|^{q}}{e^{\eta \varrho_{2}}}\int_{0}^{1}h\left(\frac{t^{\alpha}}{2^{\alpha}}\right)dt\bigg)^{\frac{1}{q}}\bigg]. \end{align}$

4. Conclusions

The Hadamard inequalities presented in this work behave as generalized formulas which generate a number of fractional integral inequalities for all kinds of convex functions connected with exponentially $(\alpha, h-m)$ -convex function. Inequalities for Riemann-Liouville fractional integrals can also be deduced from the results of this paper. This work can be extended for other kinds of fractional integral operators exist in the literature.

Acknowledgments

We would like to thank reviewers for evaluating the work and giving useful suggestions.

Conflict of interest

The authors do not have competing interests.

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