Recently, researchers have become interested in modelling, monitoring, and treatment of hepatitis B virus infection. Understanding the various connections between pathogens, immune systems, and general liver function is crucial. In this study, we propose a higher-order stochastically modified delay differential model for the evolution of hepatitis B virus transmission involving defensive cells. Taking into account environmental stimuli and ambiguities, we presented numerical solutions of the fractal-fractional hepatitis B virus model based on the exponential decay kernel that reviewed the hepatitis B virus immune system involving cytotoxic T lymphocyte immunological mechanisms. Furthermore, qualitative aspects of the system are analyzed such as the existence-uniqueness of the non-negative solution, where the infection endures stochastically as a result of the solution evolving within the predetermined system's equilibrium state. In certain settings, infection-free can be determined, where the illness settles down tremendously with unit probability. To predict the viability of the fractal-fractional derivative outcomes, a novel numerical approach is used, resulting in several remarkable modelling results, including a change in fractional-order $ \delta $ with constant fractal-dimension $ \varpi $, $ \delta $ with changing $ \varpi $, and $ \delta $ with changing both $ \delta $ and $ \varpi $. White noise concentration has a significant impact on how bacterial infections are treated.
Citation: Maysaa Al Qurashi, Saima Rashid, Fahd Jarad. A computational study of a stochastic fractal-fractional hepatitis B virus infection incorporating delayed immune reactions via the exponential decay[J]. Mathematical Biosciences and Engineering, 2022, 19(12): 12950-12980. doi: 10.3934/mbe.2022605
Recently, researchers have become interested in modelling, monitoring, and treatment of hepatitis B virus infection. Understanding the various connections between pathogens, immune systems, and general liver function is crucial. In this study, we propose a higher-order stochastically modified delay differential model for the evolution of hepatitis B virus transmission involving defensive cells. Taking into account environmental stimuli and ambiguities, we presented numerical solutions of the fractal-fractional hepatitis B virus model based on the exponential decay kernel that reviewed the hepatitis B virus immune system involving cytotoxic T lymphocyte immunological mechanisms. Furthermore, qualitative aspects of the system are analyzed such as the existence-uniqueness of the non-negative solution, where the infection endures stochastically as a result of the solution evolving within the predetermined system's equilibrium state. In certain settings, infection-free can be determined, where the illness settles down tremendously with unit probability. To predict the viability of the fractal-fractional derivative outcomes, a novel numerical approach is used, resulting in several remarkable modelling results, including a change in fractional-order $ \delta $ with constant fractal-dimension $ \varpi $, $ \delta $ with changing $ \varpi $, and $ \delta $ with changing both $ \delta $ and $ \varpi $. White noise concentration has a significant impact on how bacterial infections are treated.
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Maysaa Al Qurashi, Saima Rashid, Fahd Jarad. A computational study of a stochastic fractal-fractional hepatitis B virus infection incorporating delayed immune reactions via the exponential decay[J]. Mathematical Biosciences and Engineering, 2022, 19(12): 12950-12980. doi: 10.3934/mbe.2022605
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