Research article Special Issues

Stability and estimation problems related to a stage-structured epidemic model

  • Received: 14 January 2019 Accepted: 08 May 2019 Published: 20 May 2019
  • In this work, we consider a class of stage-structured Susceptible-Infectious (SI) epidemic models which includes, as special cases, a number of models already studied in the literature. This class allows for n different stages of infectious individuals, with all of them being able to infect susceptible individuals, and also allowing for different death rates for each stage—this helps to model disease induced mortality at all stages. Models in this class can be considered as a simplified modelling approach to chronic diseases with progressive severity, as is the case with AIDS for instance. In contradistinction to most studies in the literature, we consider not only the questions of local and global stability, but also the observability problem. For models in this class, we are able to construct two different state-estimators: the first one being the classical high-gain observer, and the second one being the extended Kalman filter. Numerical simulations indicate that both estimators converge exponentially fast, but the former can have large overshooting, which is not present in the latter. The Kalman observer turns out to be more robust to noise in measurable data.

    Citation: Mamadou L. Diouf, Abderrahman Iggidr, Max O. Souza. Stability and estimation problems related to a stage-structured epidemic model[J]. Mathematical Biosciences and Engineering, 2019, 16(5): 4415-4432. doi: 10.3934/mbe.2019220

    Related Papers:

  • In this work, we consider a class of stage-structured Susceptible-Infectious (SI) epidemic models which includes, as special cases, a number of models already studied in the literature. This class allows for n different stages of infectious individuals, with all of them being able to infect susceptible individuals, and also allowing for different death rates for each stage—this helps to model disease induced mortality at all stages. Models in this class can be considered as a simplified modelling approach to chronic diseases with progressive severity, as is the case with AIDS for instance. In contradistinction to most studies in the literature, we consider not only the questions of local and global stability, but also the observability problem. For models in this class, we are able to construct two different state-estimators: the first one being the classical high-gain observer, and the second one being the extended Kalman filter. Numerical simulations indicate that both estimators converge exponentially fast, but the former can have large overshooting, which is not present in the latter. The Kalman observer turns out to be more robust to noise in measurable data.


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    [1] Z. Shuai and P. van den Driessche, Global stability of infectious disease models using Lyapunov functions, SIAM J. Appl. Math., 73 (2013), 1513-1532.
    [2] A. Iggidr, J. Mbang, G. Sallet, et al., Multi-compartment models. Discrete Contin. Dyn. Syst. Supplements, suppl. volume(Dynamical Systems and Differential Equations. Proceedings of the 6th AIMS International Conference), 2007, 506–519.
    [3] H. Guo and M. Y. Li, Global dynamics of a staged progression model for infectious diseases, Math. Biosci. Eng., 3 (2006), 513–525.
    [4] P. van den Driessche and J. Watmough, Reproduction numbers and sub-threshold endemic equi- libria for compartmental models of disease transmission, Math. Biosci., 180 (2002), 29–48.
    [5] J.-P. LaSalle, Stability theory for ordinary differential equations. J. Differ. Equations, 4 (1968), 57–65.
    [6] J.-P. Gauthier, H. Hammouri and S. Othman, A simple observer for nonlinear systems applications to bioreactors. IEEE Trans. Autom. Control, 37 (1992), 875–880.
    [7] G. Bornard and H. Hammouri, A high gain observer for a class of uniformly observable systems. In Proceedings of the 30th IEEE Conference on Decision and Control, 1991, 1494–1496.
    [8] F. Deza, E. Busvelle, J.-P. Gauthier, et al., High gain estimation for nonlinear systems, Syst. Control Lett., 18 (1992), 295–299.
    [9] A. Guiro, A. Iggidr, D. Ngom, et al., On the stock estimation for some fishery systems, Rev. Fish Biol. Fisher., 19 (2009), 313–327.
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