Fabrication of biodegradable films using <sc>l</sc>-lactate as a chiral material to produce circularly polarized light

Po-Yeh Lin; Chien-Ming Chen; Jen-Ai Lee; Yu-Chia Cheng; Po-Yeh Lin; Chien-Ming Chen; Jen-Ai Lee; Yu-Chia Cheng

doi:10.3934/bioeng.2022024

AIMS Bioengineering

2022, Volume 9, Issue 4: 337-347. doi: 10.3934/bioeng.2022024

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Fabrication of biodegradable films using l-lactate as a chiral material to produce circularly polarized light

1.
School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan
2.
Department of Electro-Optical Engineering, National Taipei University of Technology, Taipei, Taiwan

Received: 12 September 2022 Revised: 06 November 2022 Accepted: 13 November 2022 Published: 18 November 2022

Optical activity and its relation to molecular chirality are significant in the measurement of optical rotation or circular dichroism characteristics to determine the absolute configuration of a chiral molecule. A quarter-wave plate, which is usually made from quartz, can convert linearly polarized light into circularly polarized light. In this study, we suggest using l-lactic acid (l-LA), a chiral material, and a water-based transparent glue to produce biodegradable films. Adjusting the number of thin layers, which are deposited from the mixture of l-LA and polyvinyl alcohol, leads to different phase differences, forming l-LA films. A modified microscope system was used to observe the appearance of the l-LA wave plates. Six layers and 0.8% l-LA solution were the optimal conditions to fabricate an l-LA film. The circular polarization experiment showed that the changes in maximum and minimum light intensity were within 2% compared to the average light intensity at a specific angle of the l-LA film. The performance of the l-LA film was consistent with that of a commercial quarter-wave plate. In conclusion, circularly polarized light was successfully produced using the l-LA film. The biodegradable l-LA film has widespread application in the field of biomedicine. Featured Application: l-Lactic acid film uses biodegradable and biocompatible materials. It can produce circularly polarized light and is beneficial for application in biomedicine.
- quarter-wave plates,
- circularly polarized light,
- l-lactic acid,
- biodegradable
Citation: Po-Yeh Lin, Chien-Ming Chen, Jen-Ai Lee, Yu-Chia Cheng. Fabrication of biodegradable films using l-lactate as a chiral material to produce circularly polarized light[J]. AIMS Bioengineering, 2022, 9(4): 337-347. doi: 10.3934/bioeng.2022024

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Abstract

Optical activity and its relation to molecular chirality are significant in the measurement of optical rotation or circular dichroism characteristics to determine the absolute configuration of a chiral molecule. A quarter-wave plate, which is usually made from quartz, can convert linearly polarized light into circularly polarized light. In this study, we suggest using l-lactic acid (l-LA), a chiral material, and a water-based transparent glue to produce biodegradable films. Adjusting the number of thin layers, which are deposited from the mixture of l-LA and polyvinyl alcohol, leads to different phase differences, forming l-LA films. A modified microscope system was used to observe the appearance of the l-LA wave plates. Six layers and 0.8% l-LA solution were the optimal conditions to fabricate an l-LA film. The circular polarization experiment showed that the changes in maximum and minimum light intensity were within 2% compared to the average light intensity at a specific angle of the l-LA film. The performance of the l-LA film was consistent with that of a commercial quarter-wave plate. In conclusion, circularly polarized light was successfully produced using the l-LA film. The biodegradable l-LA film has widespread application in the field of biomedicine. Featured Application: l-Lactic acid film uses biodegradable and biocompatible materials. It can produce circularly polarized light and is beneficial for application in biomedicine.

Acknowledgments

This research is based upon work supported by the Ministry of Science and Technology (MOST) of Taiwan under the award number 110-2637-E-027-002 and 109-2813-C-027-016-E.

Conflict of interest

The authors declare no conflict of interest.

Author contributions

Formal analysis, Po-Yeh Lin; Investigation, Jen-Ai Lee; Methodology, Chien-Ming Chen and Yu-Chia Cheng; Project administration, Chien-Ming Chen and Jen-Ai Lee; Visualization, Yu-Chia Cheng; Writing – original draft, Po-Yeh Lin; Writing – review & editing, Chien-Ming Chen.

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