Cellular Automata have been successfully used to model evolution of complex systems based on simples rules. In this paper we introduce controlled cellular automata to depict the dynamics of systems with controls that can affect their evolution. Using theory from discrete control systems, we derive results for the control of cellular automata in specific cases. The paper is mostly oriented toward two applications: fire spreading; morphogenesis and tumor growth. In both cases, we illustrate the impact of a control on the evolution of the system. For the fire, the control is assumed to be either firelines or firebreaks to prevent spreading or dumping of water, fire retardant and chemicals (foam) on the fire to neutralize it. In the case of cellular growth, the control describes mechanisms used to regulate growth factors and morphogenic events based on the existence of extracellular matrix structures called fractones. The hypothesis is that fractone distribution may coordinate the timing and location of neural cell proliferation, thereby guiding morphogenesis, at several stages of early brain development.
Citation: Achilles Beros, Monique Chyba, Oleksandr Markovichenko. Controlled cellular automata[J]. Networks and Heterogeneous Media, 2019, 14(1): 1-22. doi: 10.3934/nhm.2019001
[1] | Kyungkeun Kang, Dongkwang Kim . Existence of generalized solutions for Keller-Segel-Navier-Stokes equations with degradation in dimension three. Mathematics in Engineering, 2022, 4(5): 1-25. doi: 10.3934/mine.2022041 |
[2] | Lucio Boccardo . A "nonlinear duality" approach to $ W_0^{1, 1} $ solutions in elliptic systems related to the Keller-Segel model. Mathematics in Engineering, 2023, 5(5): 1-11. doi: 10.3934/mine.2023085 |
[3] | Lucas C. F. Ferreira . On the uniqueness of mild solutions for the parabolic-elliptic Keller-Segel system in the critical $ L^{p} $-space. Mathematics in Engineering, 2022, 4(6): 1-14. doi: 10.3934/mine.2022048 |
[4] | Alberto Farina . Some results about semilinear elliptic problems on half-spaces. Mathematics in Engineering, 2020, 2(4): 709-721. doi: 10.3934/mine.2020033 |
[5] | Takeyuki Nagasawa, Kohei Nakamura . Asymptotic analysis for non-local curvature flows for plane curves with a general rotation number. Mathematics in Engineering, 2021, 3(6): 1-26. doi: 10.3934/mine.2021047 |
[6] | Giuseppe Procopio, Massimiliano Giona . Bitensorial formulation of the singularity method for Stokes flows. Mathematics in Engineering, 2023, 5(2): 1-34. doi: 10.3934/mine.2023046 |
[7] | Italo Capuzzo Dolcetta . The weak maximum principle for degenerate elliptic equations: unbounded domains and systems. Mathematics in Engineering, 2020, 2(4): 772-786. doi: 10.3934/mine.2020036 |
[8] | Riccardo Adami, Raffaele Carlone, Michele Correggi, Lorenzo Tentarelli . Stability of the standing waves of the concentrated NLSE in dimension two. Mathematics in Engineering, 2021, 3(2): 1-15. doi: 10.3934/mine.2021011 |
[9] | L. Dieci, Fabio V. Difonzo, N. Sukumar . Nonnegative moment coordinates on finite element geometries. Mathematics in Engineering, 2024, 6(1): 81-99. doi: 10.3934/mine.2024004 |
[10] | Massimiliano Giona, Luigi Pucci . Hyperbolic heat/mass transport and stochastic modelling - Three simple problems. Mathematics in Engineering, 2019, 1(2): 224-251. doi: 10.3934/mine.2019.2.224 |
Cellular Automata have been successfully used to model evolution of complex systems based on simples rules. In this paper we introduce controlled cellular automata to depict the dynamics of systems with controls that can affect their evolution. Using theory from discrete control systems, we derive results for the control of cellular automata in specific cases. The paper is mostly oriented toward two applications: fire spreading; morphogenesis and tumor growth. In both cases, we illustrate the impact of a control on the evolution of the system. For the fire, the control is assumed to be either firelines or firebreaks to prevent spreading or dumping of water, fire retardant and chemicals (foam) on the fire to neutralize it. In the case of cellular growth, the control describes mechanisms used to regulate growth factors and morphogenic events based on the existence of extracellular matrix structures called fractones. The hypothesis is that fractone distribution may coordinate the timing and location of neural cell proliferation, thereby guiding morphogenesis, at several stages of early brain development.
The main purpose of this note is to provide an alternative construction of nonnegative and nonradially symmetric initial data for some Keller–Segel-type models which will enforce finite or infinite blowup. Consider the following functional:
$ F(u,v):=∫Ω(ulogu−uv+12|∇v|2+12v2)dx, $
|
where $ \Omega \subset \mathbb{R}^2 $ is a bounded domain with $ C^2 $ boundary $ \partial \Omega $ and a pair of nonnegative smooth functions $ (u, v) $. The main result of this note is stated as follows.
Theorem 1.1. For any $ M > 0 $ and $ \Lambda \in (4\pi, \infty) $ there exists a pair of nonnegative functions $ (u_0, v_0) \in (C^\infty(\overline{\Omega}))^2 $ satisfying
$ {‖u0‖L1(Ω)=Λ,F(u0,v0)<−M. $
|
The above functional $ \mathcal{F}(u, v) $ appears in the study of the minimal Keller–Segel system:
$ {ut=Δu−∇⋅(u∇v)x∈Ω,t>0,vt=Δv−v+ux∈Ω,t>0,∂νu=∂νv=0x∈∂Ω,t>0,u(x,0)=u0(x),v(x,0)=v0(x),x∈Ω, $
|
(1.1) |
and also one of the following chemotaxis model featuring a signal-dependent motility function of the negative exponential type:
$ {ut=Δ(e−vu)x∈Ω,t>0,vt=Δv−v+ux∈Ω,t>0,∂νu=∂νv=0x∈∂Ω,t>0,u(x,0)=u0(x),v(x,0)=v0(x),x∈Ω. $
|
(1.2) |
Classical positive solutions of (1.1) satisfy the following energy-dissipation identity ([4,9]):
$ ddtF(u,v)(t)+∫Ωu|∇logu−∇v|2dx+‖vt‖2L2(Ω)=0, $
|
while for the classical solutions to (1.2), there holds ([2]):
$ ddtF(u,v)(t)+∫Ωue−v|∇logu−∇v|2dx+‖vt‖2L2(Ω)=0. $
|
In both cases, the above energy identities will immediately give rise to the a priori upper bound for $ \mathcal{F}(u, v)(t) $. On the other hand, for any given initial data of small total mass such that $ \|u_0\|_{L^1(\Omega)} < 4\pi $, one could derive a lower bound for the energy functional and then the classical solutions of both systems (1.1) and (1.2) exist globally in time and remain bounded uniformly in the two-dimensional setting (see [2,4,7,9]). For large data, unbounded solutions of the above problems could be constructed based on observations of the variational structure of the stationary problem and by taking an advantage of the subtle connection between its associated functional with the energy $ \mathcal{F} $. In [5] the authors introduced a transformation problem of the original system (1.1) with the unknowns being the cell density and the relative signal concentration. Then they constructed unbounded solutions for the transformed problem, which in turn implied blowup of the original one.
In this note we would rather to construct an unbounded solution to the original system (1.1) or (1.2) in a more direct way. To this aim, let us sketch the main idea of the construction of an unbounded solution following [11] (see also [5]). First, the corresponding stationary solutions $ (u_s, v_s) $ to (1.1) or (1.2) satisfy the following problem:
$ {vs−Δvs=Λ∫Ωevsdxevsin Ω,us=Λ∫Ωevsdxevsin Ω,∂vs∂ν=0on ∂Ω, $
|
(1.3) |
for some $ \Lambda > 0 $. Denote
$ \mathcal{S}(\Lambda) : = \left\{ (u_s, v_s) \in C^2(\overline{\Omega}) : (u_s, v_s ) \mbox{ is a solution to (1.3) } \right\} $ |
for $ \Lambda > 0 $. By [5,Lemma 3.5] and [10,Theorem 1], for $ \Lambda \not\in 4\pi \mathbb{N} $ there exists some $ C > 0 $ such that
$ \sup \{ \|(u_s, v_s)\|_{L^\infty (\Omega)} : (u_s, v_s) \in \mathcal{S}(\Lambda) \} \leq C $ |
and
$ \mathcal{F}_\ast(\Lambda) : = \inf \{ \mathcal{F}(u_s, v_s) : (u_s, v_s) \in \mathcal{S}(\Lambda) \} \geq - C. $ |
On the other hand, let $ (u, v) $ be the classical positive solution to (1.1) or (1.2) in $ \Omega \times (0, \infty) $. If the solution is uniform-in-time bounded, by the compactness method (cf. [13,Lemma 3.1]), there exist a sequence of time $ \{t_k\} \subset (0, \infty) $ and a solution $ (u_s, v_s) $ to (1.3) with $ \Lambda = \|u_0\|_{L^1(\Omega)} $ such that $ \lim\limits_{k \rightarrow \infty} t_k = \infty $ and that
$ \lim\limits_{k \rightarrow \infty} (u(t_k), v(t_k)) = (u_s, v_s) \quad \mbox{in}C^2(\overline{\Omega}), $ |
as well as
$ \mathcal{F}(u_s, v_s) \leq \mathcal{F}(u_0, v_0). $ |
Thus taking account of the above discussion, for a pair of nonnegative functions $ (u_0, v_0) $ satisfying
$ {‖u0‖L1(Ω)=Λ∉4πN,F(u0,v0)<F∗(Λ), $
|
(1.4) |
the corresponding solution must be unbounded or blow up in finite time.
Recently in [2], we constructed nonnegative initial data satisfying (1.4) when $ \Lambda \in (8\pi, \infty) $ in the radially symmetric case, which differs from those given in [5]. However, it was left open whether our idea for a construction of adequate initial data can be extended to the nonradial symmetric case if $ \Lambda \in (4\pi, 8 \pi) $. Theorem 1.1 of the present work gives an affirmative answer to this question and as a consequence, we have an alternative proof of the following corollaries ([5]).
Corollary 1.2. For any $ \Lambda\in(4\pi, \infty)\backslash4\pi\mathbb{N} $ there exists a nonnegative initial datum $ (u_0, v_0) $ satisfying (1.4) such that the corresponding classical solution of $(1.1)$ satisfies either:
● exists globally in time and $ \limsup\limits_{t\rightarrow \infty}(\|u(t)\|_{L^\infty(\Omega)} + \|v(t)\|_{L^\infty(\Omega)}) = \infty $;
● blows up in finite time.
Remark 1.3. Finite time blowup solutions of the corresponding parabolic-elliptic system are constructed if $ \Lambda > 4\pi $ in [8].
As to the system (1.2), global existence of classical solutions with any nonnegative initial data was guaranteed in [2], which excluded the possibility of finite-time blowup. Hence, we arrive at the following:
Corollary 1.4. For any $ \Lambda\in(4\pi, \infty)\backslash4\pi\mathbb{N} $ there exists a nonnegative initial datum $ (u_0, v_0) $ satisfying (1.4) such that the corresponding global classical solution of $(1.2)$ blows up at time infinity.
In previous works [3,6,12,13], nonnegative initial data with large negative energy were constructed in several modified situations, e.g., the higher dimensional setting, the nonlinear diffusion case, the nonlinear sensitivity case and the indirect signal case. In those works, the initial datum has a concentration at an interior point of $ \Omega $. Similarly, in our precedent work [2], we constructed an initial datum which concentrates at the origin based on certain perturbation of the rescaled explicit solutions to the elliptic system
$ {−ΔV=Ux∈R2,eV=Ux∈R2,∫R2U=8π, $
|
provided that the total mass $ \Lambda > 8\pi $. However, without the radially symmetric requirement and when $ 4\pi < \Lambda < 8\pi $, we need to construct an initial datum that concentrates at a boundary point. To this aim, some cut-off and folding-up techniques are introduced. Besides, a lemma of analysis (Lemma 2.2) plays a crucial role in estimating the value of each individual integral in the energy functional and in order to get vanishing estimations of the error terms, the radius of the cut-off function used in our case needs to depend on the rescaled parameter as well, which in contrast was fixed in the radially symmetric case in [2].
A straightforward calculation leads us to the following lemma.
Lemma 2.1. For any $ \lambda \geq 1 $ and $ r \in (0, 1) $, the functions
$ u_\lambda (x) : = \frac{8\lambda^2}{(1+\lambda^2|x|^2)^2}, \quad v_{\lambda} (x) : = 2 \log \frac{1+\lambda^2}{1+\lambda^2|x|^2} + \log 8 \qquad \mathit{\mbox{for all}} \ x \in \mathbb{R}^2, $ |
satisfy
$ ∫R2uλdx=8π,uλ(x)≤8λ2,vλ(x)>log8>0in Br(0):={x∈R2||x|<r}. $
|
Since $ \partial \Omega $ is $ C^2 $ class, for any boundary point $ P\in \partial \Omega $ there exist some $ R^\prime = R^\prime_{P}\in (0, 1) $ and some $ C^2 $ function $ \gamma_{P}: \mathbb{R} \to \mathbb{R} $ such that
$ \Omega \cap B_{R^\prime} (0) = \{ (x_1, x_2)\in B_{R^\prime}(0)\, |\, x_2 > \gamma_{P} (x_1) \} $ |
(cf. [1,Appendix C.1]). Moreover since $ \Omega $ is a bounded domain, we can find some point $ P_0 = (P_1, P_2) \in \partial \Omega $ satisfying that there exists $ R \in (0, R^\prime) $ such that
$ (γP0)′′(x1)≥0for all |P1−x1|<R. $
|
(2.1) |
By translation, we may assume $ P_0 = (0, 0) $. Hereafter we fix the above $ R \in (0, 1) $ and $ \gamma = \gamma_{P_0} $. In this setting, we have the following lemma:
Lemma 2.2. Let $ f: \mathbb{R}^2 \to \mathbb{R} $ be a radially symmetric, nonnegative and continuous function. For any $ r\in(0, R) $ it follows that
$ \frac{1}{2}\int_{B_r(0)} f(x)\, dx -K(R) \left(\sup\limits_{x\in B_r(0)}f(x)\right) \cdot r^3 \leq \int_{B_r(0) \cap \Omega} f(x)\, dx \leq \frac{1}{2}\int_{B_r(0)} f(x)\, dx, $ |
where
$ K(R):=max|ξ|≤Rγ′′(ξ)>0. $
|
(2.2) |
Proof. We first note that for any $ r\in (0, R) $,
$ \Omega \cap B_r(0) = \{ (x_1, x_2)\in B_r(0)\, |\, x_2 > \gamma (x_1) \}. $ |
Since $ \gamma(0) = 0 $ and the assumption (2.1), it follows by Taylor's theorem that for all $ x_1 \in (-R, R) $ we have
$ \gamma^\prime(0)x_1 \leq \gamma (x_1) \leq \gamma^\prime(0)x_1 + \frac{1}{2}K(R) \cdot x_1^2, $ |
where $ K(R) : = \max_{|\xi| \leq R}\gamma^{\prime\prime}(\xi) > 0 $. Thus we can deduce that
$ A_{+\varepsilon} \subset (\Omega \cap B_r(0)) \subset A, $ |
where
$ A+ε:={(x1,x2)∈Br(0)|x2>γ′(0)x1+12K(R)⋅r2},A:={(x1,x2)∈Br(0)|x2>γ′(0)x1}. $
|
By denoting
$ B+ε:={(x1,x2)∈Br(0)|γ′(0)x1+12K(R)⋅r2≥x2>γ′(0)x1}, $
|
we confirm that
$ A_{+\varepsilon} = A \setminus B_{+\varepsilon}. $ |
Since the radial symmetry of $ f $ implies
$ \int_{A}f(x)\, dx = \frac{1}{2} \int_{B_r(0)}f(x)\, dx, $ |
we have
$ \frac{1}{2} \int_{B_r(0)}f(x)\, dx - \int_{B_{+\varepsilon}}f(x)\, dx \leq \int_{\Omega \cap B_r(0)} f(x)\, dx \leq \frac{1}{2} \int_{B_r(0)}f(x)\, dx. $ |
Since
$ |B_{+\varepsilon}| \leq \frac{1}{2} K(R) r^2 \cdot 2r = K(R) r^3, $ |
we have that
$ 12∫Br(0)f(x)dx−(supx∈Br(0)f(x))⋅K(R)⋅r3≤∫Ω∩Br(0)f(x)dx≤12∫Br(0)f(x)dx, $
|
which concludes the proof.
For any $ 0 < \eta_1 < \eta_2 $ we can construct a radially symmetric function $ \phi_{\eta_2, \eta_1} \in C^\infty (\mathbb{R}^2) $ satisfying
$ \phi_{\eta_2, \eta_1}(B(0, \eta_1)) = \{1\}, \ 0\leq \phi_{\eta_2, \eta_1} \leq 1, \ \phi_{\eta_2, \eta_1}( \mathbb{R}^2 \setminus B(0, \eta_2) ) = \{0\}, \ x \cdot \nabla \phi_{\eta_2, \eta_1}(x) \leq 0. $ |
For any $ \lambda > \max\{1, (\frac{4}{R})^{\frac{6}{5}}\} $, we fix
$ r:=λ−56,r1:=r2, $
|
and then $ 0 < r_1 < r < \min\{1, \frac{R}{4}\} $. Noting that
$ f(\lambda): = 1 - \frac{1}{1+(\lambda r_1)^2} = 1-\frac{4}{4+\lambda^{\frac{1}{3}}} \nearrow 1 \quad \mbox{ as } \lambda \to \infty, $ |
and by the increasing property of $ f $, we can find $ \lambda_\ast > \max\{1, (\frac{4}{R})^{\frac{6}{5}}\} $ such that
$ 4 \pi \cdot f(\lambda_\ast)-8K(R) \lambda_{\ast}^{-\frac{1}{2}} > 2\pi, $ |
where $ K(R) $ is defined in (2.2). Here we confirm that for any $ \lambda > \lambda_\ast $,
$ 4 \pi \cdot f(\lambda)-8K(R) \lambda^{-\frac{1}{2}} > 2\pi. $ |
Now we define the pair
$ (u_0, v_0) : = (au_\lambda \phi_{r, r_1}\chi_{\Omega}, av_{\lambda } \phi_{\frac{R}{2}, \frac{R}{4}} \chi_{\Omega} ) $ |
with some $ a > 0 $. Here we remark that $ u_0 $ and $ v_0 $ are nonnegative functions belonging to $ C^\infty(\overline{\Omega}) $.
Lemma 2.3. Let $ \Lambda \in (4\pi, \infty) $. For $ \lambda > \lambda_\ast $ there exists
$ a=a(λ)∈(Λ4π,Λ2π) $
|
(2.3) |
such that
$ ∫Ωu0dx=Λ. $
|
(2.4) |
Proof. Firstly by changing variables, we see that
$ ∫B(0,ℓ)uλdx=8∫B(0,λℓ)dy(1+|y|2)2=8π∫(λℓ)20dτ(1+τ)2=8π⋅(1−11+(λℓ)2) for ℓ>0, $
|
(2.5) |
and that
$ 8π⋅(1−11+(λr1)2)<∫Br(0)uλϕr,r1dx<8π⋅(1−11+(λr)2). $
|
Here in light of the radial symmetry of $ u_\lambda \phi_{r, r_1} $, we can invoke Lemma 2.2 to have
$ 4π⋅(1−11+(λr1)2)−K(R)8λ2r3<∫Ωuλϕr,r1χΩdx<4π⋅(1−11+(λr)2), $
|
where we used
$ \max\limits_{x\in B_r(0)} u_\lambda \phi_{r, r_1}(x) = 8\lambda^2\quad \mbox{and}\quad \int_\Omega u_\lambda \phi_{r, r_1}\chi_{\Omega}\, dx = \int_{B_r(0)\cap \Omega} u_\lambda \phi_{r, r_1}\, dx. $ |
By the choice of $ r > 0 $, we have
$ 4π⋅f(λ)−8K(R)λ−12<∫Ωuλϕr,r1χΩdx. $
|
Therefore for any $ \lambda > \lambda_\ast $ we find some $ a = a(\lambda) $ satisfying
$ Λ4π<a<Λ2π $
|
and (2.4). We conclude the proof.
Lemma 2.4. There exists $ C > 0 $ such that for all $ \lambda > \lambda_\ast $,
$ ∫Ωu0logu0dx≤8πalogλ+C, $
|
(2.6) |
where $ a = a(\lambda) $ is defined in Lemma 2.3.
Proof. Since $ s\log s \leq t\log t +\frac{1}{e} $ for $ s\leq t $ and $ u_0 \leq a u_\lambda \chi_{B_r(0)\cap\Omega} $, it follows
$ ∫Ωu0logu0dx≤∫Ω(auλχBr(0)∩Ω)log(auλχBr(0)∩Ω)dx+|Ω|e≤a∫ΩuλχBr(0)∩Ωloguλdx+(aloga+e−1)∫Ωuλdx+|Ω|e. $
|
Since $ \log u_\lambda \leq \log (8\lambda^2) = 2 \log \lambda +\log 8 $ and $ \int_\Omega u_\lambda \leq 8\pi $, we have
$ ∫Ωu0logu0dx≤2alogλ∫ΩuλχBr(0)∩Ωdx+8π(alog8+aloga+e−1)+|Ω|e. $
|
By Lemma 2.2 we obtain
$ \int_\Omega u_\lambda\chi_{B_r(0)\cap\Omega} \leq \frac{1}{2}\int_{B_r(0)} u_\lambda \leq \frac{1}{2} \int_{ \mathbb{R}^2} u_\lambda = 4\pi. $ |
Therefore
$ ∫Ωu0logu0dx≤8πalogλ+C, $
|
where we remark that the constant $ C $ is independent of $ a $ and $ \lambda $ in view of (2.3). We conclude the proof.
Lemma 2.5. There exists $ C > 0 $ such that for all $ \lambda > \lambda_\ast $,
$ ∫Ωu0v0dx≥16πa2logλ−64πa2logλ4+λ13−K(R)λ−12(2log(1+λ2)+log8)−C, $
|
(2.7) |
where $ a = a(\lambda) $ is defined in Lemma 2.3.
Proof. Using $ v_{\lambda } > 0 $ in $ B(0, r) $, $ u_0 = 0 $ on $ B(0, r)^c $ and $ r_1 < \frac{R}{4} $, we see that
$ ∫Ωu0v0dx≥a2∫B(0,r1)uλvλχBr1(0)∩Ωdx. $
|
Since $ u_\lambda v_{\lambda} $ is radially symmetric and
$ \max\limits_{x\in B_{r_1}(0)} u_\lambda v_{\lambda} (x) = 8\lambda^2 (2 \log (1+\lambda^2) + \log 8), $ |
we apply Lemma 2.2 and recall $ r_1 = 2^{-1}\lambda^{-\frac{5}{6}} $ to deduce that
$ ∫Ωu0v0dx≥12a2∫B(0,r1)uλvλdx−K(R)8λ2(2log(1+λ2)+log8)⋅r31=12a2∫B(0,r1)uλvλdx−K(R)λ−12(2log(1+λ2)+log8). $
|
Since
$ v_{\lambda} (x) > 2 \log \frac{1+\lambda^2 }{1+\lambda^2 |x|^2} \quad \mbox{ for } x \in B(0, r_1), $ |
we have that
$ 12a2∫B(0,r1)uλvλdx≥12a2∫B(0,r1)uλ⋅2log1+λ21+λ2|x|2dx>2a2logλ∫B(0,r1)uλdx−a2∫B(0,r1)uλlog(1+λ2|x|2)dx. $
|
By (2.5), it follows
$ 2a2logλ∫B(0,r1)uλdx≥2a2logλ⋅8π(1−11+(λr1)2)=16πa2logλ−64πa2logλ4+λ13. $
|
On the other hand, by (2.3) and direct calculations we see
$ a2∫B(0,r1)uλlog(1+λ2|x|2)dx=8a2∫B(0,r1)λ2log(1+λ2|x|2)(1+λ2|x|2)2dx=16πa2∫λr10slog(1+s2)(1+s2)2ds<8πa2∫∞0log(1+ξ)(1+ξ)2dξ<∞. $
|
Combining above estimates, we obtain that
$ ∫Ωu0v0dx≥16πa2logλ−64πa2logλ4+λ13−K(R)λ−12(2log(1+λ2)+log8)−C $
|
for $ \lambda > \lambda_\ast $ with some positive constant $ C $, which is independent of $ a $ and $ \lambda $ due to (2.3).
Lemma 2.6. For any $ \varepsilon_1 > 0 $ there exists $ C(\varepsilon_1) > 0 $ such that for all $ \lambda > \lambda_\ast $,
$ 12∫Ω(v20+|∇v0|2)dx≤8π(1+ε1)a2logλ+C(ε1), $
|
(2.8) |
where $ a = a(\lambda) $ is defined in Lemma 2.3.
Proof. Since
$ \dfrac{1+\lambda^2 }{1+\lambda^2 |x|^2} \leq \dfrac{1+\lambda^2 }{\lambda^2 |x|^2} \leq \left(\dfrac{2}{|x|} \right)^2 \qquad \mbox{for }\lambda > 1, $ |
we see that for $ \lambda > 1 $
$ |v_{\lambda} (x)| \leq 4 \log \frac{2}{|x|} + \log 8 \ \mbox{ in } B_1(0). $ |
Hence it follows from straightforward calculations that there is a positive constant $ C $ satisfying
$ ∫Ωv20dx≤a2∫B1(0)(4log2|x|+log8)2dx≤C, $
|
(2.9) |
where the constant $ C $ is independent of $ a $ and $ \lambda $ due to (2.3).
Moreover by Young's inequality, for any $ \varepsilon_1 > 0 $ there exists $ C^\prime (\varepsilon_1) > 0 $ such that
$ |∇v0|2=a2|ϕR2,R4∇vλ+∇ϕR2,R4vλ|2χBR2(0)∩Ω≤a2(1+ε1)ϕ2R2,R4|∇vλ|2χBR2(0)∩Ω+C′(ε1)a2|∇ϕR2,R4|2v2λχBR2(0)∩Ω. $
|
Since by (2.9) we have some $ C > 0 $ such that
$ a2∫Ω|∇ϕR2,R4|2v2λχBR2(0)∩Ωdx≤C $
|
and by the direct calculations, we have
$ |\nabla v_{\lambda} (x)| = \dfrac{4 \lambda^2 |x|}{1+\lambda^2 |x|^2}, $ |
and then we infer that
$ ∫Ω|∇v0|2dx≤a2(1+ε1)∫Ωϕ2R2,R4|∇vλ|2χBR2(0)∩Ωdx+C′(ε1)a2∫Ω|∇ϕR2,R4|2v2λdx≤16a2(1+ε1)∫BR2(0)∩Ωλ4|x|2(1+λ2|x|2)2dx+C′′(ε1) $
|
with some $ C^{\prime\prime}(\varepsilon_1) > 0 $. Since $ \dfrac{ \lambda^4 |x|^2}{(1+\lambda^2 |x|^2)^2} $ is radially symmetric, we can invoke Lemma 2.2 to see
$ ∫Ω|∇v0|2dx≤8a2(1+ε1)∫BR2(0)λ4|x|2(1+λ2|x|2)2dx+C′′(ε1), $
|
thus
$ \frac{1}{2} \int_\Omega |\nabla v_0|^2 \, dx \leq 4a^2(1+ \varepsilon_1) \int_{B_1(0)} \dfrac{ \lambda^4 |x|^2}{(1+\lambda^2 |x|^2)^2} \, dx +\frac{C^{\prime\prime}( \varepsilon_1)}{2}. $ |
On the other hand,
$ ∫B1(0)λ4|x|2(1+λ2|x|2)2dx=π∫λ20τ(1+τ)2dτ≤π∫λ2011+τdτ=πlog(1+λ2). $
|
Since $ \lambda > 1 $, it follows
$ \log (1+ \lambda^2) \leq \log (2\lambda^2) = 2\log \lambda +\log 2. $ |
Hence
$ \frac{1}{2} \int_\Omega |\nabla v_0|^2 \, dx \leq 4 \pi a^2(1+ \varepsilon_1)\cdot (2\log \lambda +\log 2) +\frac{C^{\prime\prime}( \varepsilon_1)}{2}. $ |
Therefore we conclude
$ 12∫Ω|∇v0|2dx≤8πa2(1+ε1)logλ+C(ε1), $
|
where the constant $ C(\varepsilon_1) $ is independent of $ a $ and $ \lambda $ due to (2.3).
Proof of Theorem 1.1. For any $ \Lambda \in (4\pi, \infty) $, we have $ \Lambda/{4\pi} > 1 $. In view of (2.3), we can fix $ \varepsilon_1 > 0 $ independently of $ \lambda $ such that $ (1- \varepsilon_1)a-1 > (1- \varepsilon_1)\frac{\Lambda}{4\pi}-1 > 0 $, where $ a = a(\lambda) $ is defined in Lemma 2.3. Then it follows that
$ a((1−ε1)a−1)>Λ4π((1−ε1)Λ4π−1)>0,for all λ>λ∗. $
|
(2.10) |
Collecting (2.6), (2.7) and (2.8), we infer that there exists some $ C > 0 $ such that
$ F(u0,v0)≤I1⋅logλ+I2+C, $
|
where
$ I1:=8πa−16πa2+8πa2(1+ε1)=−8πa((1−ε1)a−1),I2:=64πa2logλ4+λ13+K(R)λ−12(2log(1+λ2)+log8). $
|
Here (2.10) implies $ I_1 < 0 $ for all $ \lambda > \lambda_{\ast} $. On the other hand, we note
$ \lim\limits_{\lambda \to \infty} I_2 = 0. $ |
Based on the above discussion, for $ \Lambda \in (4\pi, \infty) $ and $ M > 0 $, we can choose some $ \lambda > \lambda_{\ast} $ such that
$ \mathcal{F}(u_0, v_0) < -M. $ |
We conclude the proof.
The authors thank the anonymous referee's careful reading and useful suggestions. K. Fujie is supported by Japan Society for the Promotion of Science (Grant-in-Aid for Early-Career Scientists; No. 19K14576). J. Jiang is supported by Hubei Provincial Natural Science Foundation under the grant No. 2020CFB602.
The authors declare no conflict of interest.
1. | Mario Fuest, Johannes Lankeit, Corners and collapse: Some simple observations concerning critical masses and boundary blow-up in the fully parabolic Keller–Segel system, 2023, 146, 08939659, 108788, 10.1016/j.aml.2023.108788 |
Left: Configuration
Let
In all the figures, red represents positive values and blue represents negative values. The uncontrolled simulation at 4 different timesteps: (a) 0, (b) 5, (c) 20 and (d) 100. The average value at the four timesteps: (a) 0.010, (b) 0.0079, (c) 0.0041 and (d) 0.00014
The pictures show a controlled simulation at the following timesteps: (a) 0, (b) 5, (c) 20, (d) 39, (e) 40, (f) 50, (g) 75, (h) 100 and (i) 150. The control switches on at 20, off at 40, back on at 50 and finally off again at 100. Notice that while the control is off, the sign is constant and the magnitude diminishes at a slow exponential rate. When the control is on, the sign alternates with each timestep and the magnitude increases at a slow exponential rate
The average is negative for the odd numbered timesteps for which the control is active. For reference, the distance from the controlled simulation at timestep 150 to a grid of zeros is 632.06
Top row using the Von Neumann neighborhood. Timesteps: (a) 1, (b) 50 and (c) 100. Bottom row using the Moore neighborhood. Timesteps: (a) 1, (b) 25 and (c) 50. Note that the Moore neighborhood promotes much faster evolution. For both
Top row:
Timesteps: (a) 1, (b) 125, (c) 175, (d) 200, (e) 210 and (f) 250. The fire is diverted by the obstacles
Timesteps: (a) 1, (b) 20, (c) 30, (d) 38, (e) 45 and (f) 100. The fire is diverted by the obstacles
Timesteps: (a) 1, (b) 20, (c) 25, (d) 35, (e) 50 and (f) 100. The fire is diverted by the obstacles
Timesteps: (a) 1, (b) 15, (c) 50 and (d) 100. A simple, uncontrolled cell growth using the Von Neumann neighborhood
Timesteps: (a) 1, (b) 5, (c) 10, (d) 30, (e) 60 and (f) 100. An uncontrolled cell growth using a neighborhood consisting of the three grid units directly above the central unit and the three side-by-side units in the row three rows below the central unit
Timesteps: (a) 0, (b) 30, (c) 60 and (d) 100. The interaction between growth of normal cells and tumor cells. The competition between the cell masses plays out at the boundary between the cell masses. The normal cells are in red, the probability of a tumor cell developing is in blue
Timesteps: (a) 1, (b) 5, (c) 15, (d) 30, (e) 60 and (f) 100. Fractones are placed along three horizontal lines. One is above the initial cell and consists of fractones that stop cell growth; they are arranged in blocks. One is in line with the initial cell (across the middle of the simulation) and greatly increases cell growth. The final line is below the intial cell and also stops cell growth. The placement of the fractones is clearly visible in (f)