Processing math: 100%
Research article Special Issues

Transcranial Doppler analysis based on computer and artificial intelligence for acute cerebrovascular disease


  • Cerebrovascular disease refers to damage to brain tissue caused by impaired intracranial blood circulation. It usually presents clinically as an acute nonfatal event and is characterized by high morbidity, disability, and mortality. Transcranial Doppler (TCD) ultrasonography is a non-invasive method for the diagnosis of cerebrovascular disease that uses the Doppler effect to detect the hemodynamic and physiological parameters of the major intracranial basilar arteries. It can provide important hemodynamic information that cannot be measured by other diagnostic imaging techniques for cerebrovascular disease. And the result parameters of TCD ultrasonography such as blood flow velocity and beat index can reflect the type of cerebrovascular disease and serve as a basis to assist physicians in the treatment of cerebrovascular diseases. Artificial intelligence (AI) is a branch of computer science which is used in a wide range of applications in agriculture, communications, medicine, finance, and other fields. In recent years, there are much research devoted to the application of AI to TCD. The review and summary of related technologies is an important work to promote the development of this field, which can provide an intuitive technical summary for future researchers. In this paper, we first review the development, principles, and applications of TCD ultrasonography and other related knowledge, and briefly introduce the development of AI in the field of medicine and emergency medicine. Finally, we summarize in detail the applications and advantages of AI technology in TCD ultrasonography including the establishment of an examination system combining brain computer interface (BCI) and TCD ultrasonography, the classification and noise cancellation of TCD ultrasonography signals using AI algorithms, and the use of intelligent robots to assist physicians in TCD ultrasonography and discuss the prospects for the development of AI in TCD ultrasonography.

    Citation: Lingli Gan, Xiaoling Yin, Jiating Huang, Bin Jia. Transcranial Doppler analysis based on computer and artificial intelligence for acute cerebrovascular disease[J]. Mathematical Biosciences and Engineering, 2023, 20(2): 1695-1715. doi: 10.3934/mbe.2023077

    Related Papers:

    [1] Rashid Al Badwawi, Mohammad Abusara, Tapas Mallick . Speed control of synchronous machine by changing duty cycle of DC/DC buck converter. AIMS Energy, 2015, 3(4): 728-739. doi: 10.3934/energy.2015.4.728
    [2] Rashmi Murali, Sangeeta Malhotra, Debajit Palit, Krishnapada Sasmal . Socio-technical assessment of solar photovoltaic systems implemented for rural electrification in selected villages of Sundarbans region of India. AIMS Energy, 2015, 3(4): 612-634. doi: 10.3934/energy.2015.4.612
    [3] Zeid Al Qaisi, Qais Alsafasfeh, Ahmad Harb . Stability impact of integrated small scale hybrid (PV/Wind) system with electric distribution network. AIMS Energy, 2018, 6(5): 832-845. doi: 10.3934/energy.2018.5.832
    [4] Virendra Sharma, Lata Gidwani . Optimistic use of battery energy storage system to mitigate grid disturbances in the hybrid power system. AIMS Energy, 2019, 7(6): 688-709. doi: 10.3934/energy.2019.6.688
    [5] Yannick Fanchette, Harry Ramenah, Camel Tanougast, Michel Benne . Applying Johansen VECM cointegration approach to propose a forecast model of photovoltaic power output plant in Reunion Island. AIMS Energy, 2020, 8(2): 179-213. doi: 10.3934/energy.2020.2.179
    [6] K. M. S. Y. Konara, M. L. Kolhe, Arvind Sharma . Power dispatching techniques as a finite state machine for a standalone photovoltaic system with a hybrid energy storage. AIMS Energy, 2020, 8(2): 214-230. doi: 10.3934/energy.2020.2.214
    [7] Fadhil Khadoum Alhousni, Firas Basim Ismail, Paul C. Okonkwo, Hassan Mohamed, Bright O. Okonkwo, Omar A. Al-Shahri . A review of PV solar energy system operations and applications in Dhofar Oman. AIMS Energy, 2022, 10(4): 858-884. doi: 10.3934/energy.2022039
    [8] Aaron St. Leger . Demand response impacts on off-grid hybrid photovoltaic-diesel generator microgrids. AIMS Energy, 2015, 3(3): 360-376. doi: 10.3934/energy.2015.3.360
    [9] HVV Priyadarshana, MA Kalhan Sandaru, KTMU Hemapala, WDAS Wijayapala . A review on Multi-Agent system based energy management systems for micro grids. AIMS Energy, 2019, 7(6): 924-943. doi: 10.3934/energy.2019.6.924
    [10] Mulualem T. Yeshalem, Baseem Khan . Design of an off-grid hybrid PV/wind power system for remote mobile base station: A case study. AIMS Energy, 2017, 5(1): 96-112. doi: 10.3934/energy.2017.1.96
  • Cerebrovascular disease refers to damage to brain tissue caused by impaired intracranial blood circulation. It usually presents clinically as an acute nonfatal event and is characterized by high morbidity, disability, and mortality. Transcranial Doppler (TCD) ultrasonography is a non-invasive method for the diagnosis of cerebrovascular disease that uses the Doppler effect to detect the hemodynamic and physiological parameters of the major intracranial basilar arteries. It can provide important hemodynamic information that cannot be measured by other diagnostic imaging techniques for cerebrovascular disease. And the result parameters of TCD ultrasonography such as blood flow velocity and beat index can reflect the type of cerebrovascular disease and serve as a basis to assist physicians in the treatment of cerebrovascular diseases. Artificial intelligence (AI) is a branch of computer science which is used in a wide range of applications in agriculture, communications, medicine, finance, and other fields. In recent years, there are much research devoted to the application of AI to TCD. The review and summary of related technologies is an important work to promote the development of this field, which can provide an intuitive technical summary for future researchers. In this paper, we first review the development, principles, and applications of TCD ultrasonography and other related knowledge, and briefly introduce the development of AI in the field of medicine and emergency medicine. Finally, we summarize in detail the applications and advantages of AI technology in TCD ultrasonography including the establishment of an examination system combining brain computer interface (BCI) and TCD ultrasonography, the classification and noise cancellation of TCD ultrasonography signals using AI algorithms, and the use of intelligent robots to assist physicians in TCD ultrasonography and discuss the prospects for the development of AI in TCD ultrasonography.



    The photovoltaic (PV) system comprises one or more solar panels connected to an inverter and other electrical hardware, utilizing the energy from the sun to produce electricity. The PV systems significantly differ in size, ranging from small ones used on rooftops to large utility-scale used in generation plants. Palestine is among the countries in the world that receive enough solar radiation. Regardless, Palestine has power shortages, with a large part of its electricity imported from other countries. Besides the inadequate electricity supply, Palestine is among the fastest-growing populations in the region. In the last 25 years, the population has doubled from 2.7 million in 1997 to almost 5.3 million in 2021 [1]. Therefore, the electricity demand is high, and the government has engaged in several strategies to compensate for the shortage. The adoption of PV systems is one of the government's policies already implemented. According to P.E.a.N.R.A, the demand is expected to rise from 1400 MWp to 2335 MWp by 2030 [2]. Studies conducted in the country show that many residential buildings are now connected with PV systems. When implementing this strategy, the relevant stakeholders should pay attention to the concept of the power factor. Power factor is defined as measuring the phase difference between current and voltage in an AC power system.

    The deployment of PV systems is regarded as one of the fastest-growing renewable sources of energy in the world today. PV systems have many advantages, including providing a safe and environmentally friendly energy source. Some of the factors that affect the success of this form of energy include the tilting of the solar PV, solar radiation, ambient temperature, wind speed, and dust deposition [3,4]. The Middle East region remains one of the areas in the world receiving high solar radiation [6]. Palestine is one of the countries with the highest solar irradiation potential. The sunshine availability is estimated to be around 3000 hours a year.

    Palestine acquires a significant portion of its energy from neighboring countries. For instance, research shows that in 2016, 91% of the electricity used in Palestine was imported [7]. Regardless, electricity is one of the most fundamental needs required in many Palestinian households. Electricity is required for various reasons, including cooling and operating the air conditioning units [8,9]. With a lack of an electricity plant in Palestine, government officials have been prompted to develop PV systems for electricity production. Essentially, this has contributed to too many challenges, prompting the Palestinian government to invest in the PV systems to deal with the challenges. The residential PV systems in Palestine have primarily bettered thanks to the favorable policy. Khatib, T. et al. illustrated that a dominant factor that may determine solar generating success or failure is energy policy [3].

    PV generation in most countries depends on the nature and type of policy developed by a country. The policy should pay significant attention to tax reduction, market capacity, financial and fiscal incentives, and technical and non-technical information dissemination. Many Palestinian cities have now embraced the PV electrical systems as the primary mode of electricity generation to serve the deficit experienced by the country.

    Currently, 39 MW PV systems have been installed. More than 93 MWp of PV systems are yet to be completed [3]. However, research has shown that Palestine faces significant policy issues that adversely affect the development of PV systems. Some identified areas include poor technical standards, low awareness, and a lack of information dissemination. Therefore, these issues have contributed to Palestine lagging in its PV electrical systems.

    Most of the residential households in Palestine are apartment buildings. Approximately 85% of the household units are owned by the residents [7]. Residential buildings are primarily found in cities, existing in neighborhoods and clusters. As illustrated by Monna, S et al., in Palestine, a 1 kW rooftop system put at optimal tilt and orientation angles generates up to 1635 kWh per year in Hebron, 1613 kWh per year in Jerusalem, 1562 kWh per year in Nablus, and 1557 kWh per year in Gaza city [7]. The outcome is crucial in determining the future of PV in the country. Residential buildings, especially in urban areas, have a high potential to maximize solar energy from the sun. The quality and type of the building remain a critical aspects to consider when determining whether to develop the PV systems.

    The use of the grid-connected PV systems culminated in several fundamental aspects influenced by the decreasing PV prices and positive government regulation practices promoting renewable energy sources [10]. Today, residential buildings, municipalities, schools, and private firms have established PV systems. In research by [11], the authors selected PV home systems operating in the last three years. According to the research, the systems yielded 4.81 kWh/kWp per day. Annually, this translates to 1756 kWh/kWp.

    As emphasized by the authors in [11], Economic assessments show that increasing the usage of PV household systems is motivating because the payback period is 4.9 years, the cost per kWh produced is 0.43 NIS (0.115 US $), and the internal rate of return is 25%. Further studies have shown the importance and significance of the PV systems in the national grid. According to studies, the PV system contributes to decreasing losses, high voltage levels, and decreasing power factors [12]. Besides increasing the electricity supply for many Palestinians, it has also improved the environment due to its clean nature. A schematic diagram of a grid-tied PV system can be found in Figure 1.

    Figure 1.  On-grid PV system block representation.

    The PV system is connected to a broader electricity network in a grid-connected version. The inverter is the intermediary between the PV system and the utility grid. The inverter's role is to convert direct current (DC) into alternating current (AC). The connection to residential buildings can take any of the three designs or models explained [14]. Researchers have paid significant attention to the residential PV systems, including their various electrical dynamics. The study by [10] looks at the various aspects of the residential PV systems installed in France. With this research, the author seeks to answer three fundamental questions, including the amount of energy produced, the level of performance, and the parameters that influence its quality [10]. In 2010, the PV systems in France produced an average power level of 1163 kWh/kWp [10]. Besides France, South American countries like Chile have also experienced a growth in the US of the PV systems as part of their electrical production system [13]. Therefore, the PV systems continue to act as a primary source of electricity for many countries and cities across the globe. The PV system offers individuals an opportunity to generate power in a clean, quiet, and reliable manner.

    Power factor is one of the most fundamental concepts in electricity. It is regarded as the phase difference between current and voltage in an AC power system. In resistive loads such as those witnessed in an electric kettle or incandescent bulb, the voltage is in phase with the current creating a unity power factor [16]. However, the same is not valid for the inductive and capacitive loads, such as in an inductive motor or a capacitor bank. The current will lag or lead the voltage leading to a non-unity power factor. In a non-unity power factor, the load utilizes both active and reactive power. As shown in Eq 1, the active power is the true power and is directly involved in the work: [17].

    PF=cos(tan1QP) (1)

    Most PV systems have a unity power factor, which means that they strictly produce active power [16]. However, research shows that this reduces the power factor in the real sense, and the grid is compelled to supply less active power with the same level of reactive power.

    Generally, the PV systems negatively influence the overall power factor, resulting in penalties, especially when corrective measures are not taken [19]. When the solar system produces energy, the active power is harnessed and fed directly to the load. Consequently, this results in lowering the active power demand from the utility. However, the reactive power emanating from the load largely remains the same [20]. The outcome is a reduction in the power factor at the grid connection. From a consumer perspective, reducing the power factor yields penalties for the grid operator. However, research has shown that several ways exist that could be used to reduce the power factor [19]. The primary strategy used revolves around the manipulation of the inverter. Stakeholders should pay significant attention to finding the most appropriate ratio between the active and reactive power. Essentially, this enables them to control the amount of active power that reaches the load, including the reactive power [20]. Capacitors could also be used in the correction of the power factor. The role of the capacitors is to reduce the magnetization of the current. Improving the power factor has many benefits, including environmental protection, reducing electricity bills, and reducing voltage drop [20]. A reduced power factor also means that the equipment has an extended life, thanks to the reduced burden on cables and other additional components.

    Figure 2.  Schematic diagram of a facility producing at unity PF [25].

    Choosing the suitable power factor is now considered one of the crucial design points of a grid-connected PV system [26]. The integration of solar energy may have a detrimental influence on the electrical infrastructure's overall power factor (PF), resulting in fines if remedial measures are not implemented. Since the solar system produces and provides solely active energy, less active energy from the grid is needed to produce the same amount of reactive energy that the solar system produces and provides [26]. Solar enterprises must reduce the likelihood of an increase in kVAR fines and penalties [27]. Adopting a Power Factor Correction device may quickly and effectively remedy this problem by installing a special type of available SCADA system [27]. Alternatively, a power factor compensator may be installed to avoid the penalty.

    In Palestine, there are several electricity distributors, each with its own set of rules and regulations regarding power factor penalties and settings. For example, the North Electricity Company decides that the power factor of a solar energy system is 0.92, which is lower than the national average [28]. This would have significant limitations, as it would reduce the actual amount of energy produced by solar energy systems in cases where there is no need to reduce its value. In addition, reducing the power factor for some systems should be based on technical studies for each case. The oversized design might have a negative impact on the network or the loads in this facility. On the other hand, after fourteen trial days of PV systems commissioning, the Jerusalem District Electricity Company operates and examines the station to determine the effect of connecting it to the network and gather the information on the ground for accurate evaluation [29]. If necessary, the company notifies the facility's owner, with each project being evaluated separately. For example, it was requested to establish a 7.5-megawatt solar power plant control system in the Al-Nuwaimah Plant [30], which would continuously modify the power factor to consistently meet the condition of the network without harming it or causing any problems to the network or its equipment. Nevertheless, there are no technical criteria for measuring the power factor of inverters under the legislation governing municipal authorities [31]. This paper mainly focuses on such authorities, which account for approximately 32.5% of the total share of electricity distributors in Palestine [3]. These parts of the network are susceptible to instability, which is achieved by not studying its status before connecting the solar energy system and determining the amount of reactive power that the inverters must compensate the network with.

    In large-scale PV power plants, the power factor and its correction are relevant both from the perspective of the plant and the grid [31]. The supply of reactive power is vital in a power grid. The amount of reactive power generated must closely balance that which is being consumed. A leading power factor due to capacitive loads causes a rise in voltage, while a lagging power factor due to inductive loads causes a reduction in the voltage [18]. However, most grid-connected PV inverters only produce active power, reducing the power factor as the grid supplies less active power but the same reactive power [32]. Further, emphasize the significance of regulating the power factor of PV plants, given that controlling and monitoring voltage is a crucial aspect of electrical grid systems. Accordingly, power factor compensation is a crucial step in attaining voltage demand in the connection point of PV plants. It is also a reliable way of easing the integration of distributed sources [33]. However, the method of handling reactive powers of photovoltaic plants depends on local legislative expectations.

    Figure 3 shows the annual temperature and irradiance values as a function of time. Palestine, as previously stated, has adequate amounts of irradiance and moderate temperatures. As a result, solar energy is one of the most promising renewable energy sources. The findings and conclusions are based on Palestinian meteorological data. Half-hourly data sets of solar irradiance and temperature are evaluated for one week, as shown in Figure 5.

    Figure 3.  Meteorological data of irradiance and temperature in Palestine.

    For load flow studies, the model has been built with ETAP 19.0.1. The Electrical Transient Analyzer Program (ETAP) is a modeling and simulation software for electrical networks that power systems engineers use to generate an "electrical digital twin" to examine electrical power system dynamics, transients, and protection. An averaged model has also been built in the Simulink environment. The latter is used to simulate changing the inverter power factor on the overall active and reactive power flow. Figure 4 shows the sub-network model consisting of a transformer in a typical town in Palestine. PV systems were distributed over five service feeders. Lengths of the cables were averaged with lumped loads at the terminals. Figure 5 shows the active and reactive power profiles for the lumped loads.

    Figure 4.  ETAP model block diagram.
    Table 1.  ETAP model parameters.
    Parameter Value
    Medium Voltage 22 kV
    Low Voltage 0.4 kV
    Transformer Capacity 1000 kVA
    Transformer X/R Ratio 13
    Service Line Length 200 m
    Service Line Impedance 0.705 + j0.406 Ω/km

     | Show Table
    DownLoad: CSV
    Figure 5.  Load profile of a dominant residential network in Palestine.

    The electric sub-network has been investigated in terms of the power factor of PV systems connected to the power grid on the overall value of the power factor of the connection point. Moreover, it was proposed to install solar energy systems with 150 kilowatts distributed across the five service feeders. The total capacity of the systems increased through 12 different scenarios after the power factor value for all photovoltaic systems was fixed. As an example, Table 2 below depicts the different scenarios addressed by adjusting the power factor of all PV installations on the grid from 1 to 0.9 leading power factor.

    Table 2.  Considered PV configuration in terms of connected capacity at each feeder in (kW).
    Scenario No. Feeder 1 Feeder 2 Feeder 3 Feeder 4 Feeder 5 Total Power (kW)
    1 10 0 0 0 0 10
    2 10 10 0 0 0 20
    3 10 10 10 0 0 30
    4 10 10 10 10 0 40
    5 10 10 10 10 10 50
    6 20 10 10 10 10 60
    7 20 20 10 10 10 70
    8 20 20 20 10 10 80
    9 20 20 20 20 10 90
    10 20 20 20 20 20 100
    11 30 20 30 20 20 120
    12 30 30 30 30 30 150

     | Show Table
    DownLoad: CSV

    The findings are broken down into three sections. The first step is to look at altering PVs' power factor on the PCC's total power factor. Second, a PV power fac-tor lookup table is given, which assists towns and electric network operators in determining the optimal power factor for PV installers to use. Finally, a suggested intuitive power fac-tor control block is described.

    As mentioned earlier, choosing the proper power factor for a grid-connected PV system could be crucial. For instance, if all connected systems are operating at a unity power factor, a decrease in the overall power factor at the point of common connection (PCC) is expected, especially at peak times. For a single system, the power factor at the PCC is given in Eq 2:

    PFPCC=cos[arctan[QloadPgridPPV]] (2)

    The grid will deliver part of the real power to the load, but all reactive power will be drawn from the grid. Hence, as seen from the grid side, the total power factor will decrease at peak generation times. Power factor degradation worsens with increasing PV generation at the unity power factor. For this reason, it can be noted how important it is to reconsider the unity power factor arrangements for integrated PV systems. Figure 6 depicts how the power factor at the PCC behaves when PV integration is increased concerning the maximum active power of the connected loads. Where the load ratio r is given by dividing the total installed PV capacity by the maximum load from Figure 5 is shown in Eq 3:

    r=Installed  PV  Capacity(kWp)Maximum  Active  Load(kW) (3)

    Alternatively, this ratio can also be the proportion of the total PV capacity of the average load. From Figure 6, it is quite clear how increasing the installed PV capacity by fixing the power factor of all systems at a universal power factor can degrade the overall power factor of the network. However, it has a delayed effect with a leading power factor. For instance, having all systems at a leading power factor of 0.95 gives the network operator a broader range to accept more PVs (as high as 80% with respect to the overall load).

    Figure 6.  PCC power factor behavior against PV power factor.

    The 3D plot is shown in Figure 7. This figure gives the PCC power factor as a function of the PV power factor and the total installed PV capacity. It gives an insight into how much PV at a given power factor will be permissible. For example, the upper area sweeps all possible combinations of the PV power factor and its relative total capacity, resulting in an overall PCC power factor of 0.90 and higher. On the other side, unacceptable combinations are given by the areas at the slope of the graph. These combinations give an alarming overall power factor of less than 0.50. These findings are being widely noticed with the PV integration surge in areas like Palestine. Network operators and municipalities are more concerned about the PCC power factor than ever. Some are already requesting a complete grid impact study before getting the license to install a PV system. Nevertheless, such studies are still immature to fully address the effect of the PV power factor on the PCC power factor. Thus, this paper is considered an excellent reference for interested parties in power factor assessment.

    Figure 7.  PCC power factor behavior against PV power factor.

    This section develops a lookup table to help network operators and municipalities decide on the best power factor settings for any added PV systems added to their grid. Based on Figure 7, the values shown in Table 3 were established. In the first column to the left, the power ratio parameter represents the PV system's peak power to the peak power demand within the network under consideration. However, the first row refers to the proper PV system's power factor, which should be selected to get the overall power factor shown in the table. The proposed lookup table serves as a good decision-making criterion where no exhaustive grid impact studies are applicable. It is evident in small villages where they cannot acquire grid-scale data or cannot afford costly studies. It can also help predict the future overall power factor if excessive PV penetration occurs. For instance, adding more than 50% of the overall capacity can drastically reduce the overall grid power factor.

    Table 3.  A lookup table for PV power factor concerning total PV penetration.
    1 0.99 0.98 0.97 0.96 0.95 0.91
    5.0% 94.0% 94.1% 94.2% 94.2% 94.3% 94.3% 94.5%
    10.0% 93.4% 94.8% 94.0% 94.1% 94.2% 94.3% 94.7%
    15.0% 92.8% 93.4% 93.7% 93.9% 94.1% 94.3% 94.9%
    20.0% 92.2% 93.1% 93.5% 93.8% 94.0% 94.3% 95.2%
    25.0% 91.5% 92.7% 93.2% 93.6% 94.0% 94.2% 95.4%
    30.0% 90.6% 92.3% 92.9% 93.4% 93.8% 94.2% 95.7%
    35.0% 89.5% 91.7% 92.5% 93.2% 93.7% 94.2% 96.0%
    40.0% 88.2% 91.1% 92.2% 93.0% 93.6% 94.2% 96.3%
    45.0% 86.4% 90.5% 91.7% 92.7% 91.8% 94.1% 96.7%
    50.0% 84.0% 89.4% 91.1% 92.3% 91.0% 94.1% 97.1%
    55.0% 80.8% 88.0% 90.4% 91.9% 91.0% 94.0% 97.4%
    60.0% 77.0% 86.3% 89.7% 91.4% 91.0% 94.0% 97.7%
    65.0% 71.6% 83.8% 88.2% 90.8% 91.0% 93.9% 97.7%
    70.0% 63.5% 78.4% 85.0% 89.5% 91.0% 93.8% 92.8%
    80.0% 43.5% 63.6% 76.3% 86.0% 91.0% 93.5% 76.7%
    90.0% 22.3% 32.8% 39.7% 45.5% 51.7% 59.1% 39.0%
    100.0% 1.1% 2.0% 3.0% 5.0% 12.4% 24.7% 1.3%

     | Show Table
    DownLoad: CSV

    To elaborate on how fixing the power factor at a constant value could affect the output of a PV System, Figure 8 shows real-time data from two identical PV systems at different inverters' power factors. As can be seen, the system with a 0.92 power factor has an in the parallel generation of reactive power. This reactive power can be helpful at peak times when the power factor at the connection point is expected to decrease. However, there could be a counterproductive effect of this excess reactive power at low generation times.

    Figure 8.  Active and Reactive power for two PV systems with different PF settings.

    As concluded, setting the PV system on a constant power factor may only be helpful for specific periods, specifically at peak generation times. As shown in Figure 9, the inverter has a maximum capacity in terms of kVAs. When the power factor is set at unity, the inverter injects only active power at its maximum capacity. However, it means that less active power is injected when the inverter operates at something other than a unity power factor. Hence, an interactive power factor controller can be more realistic. Such a controller is responsible for monitoring the overall power factor at the PCC. Then it acts by sending a command to the inverter to charge the power factor to maintain a proper one at the PCC.

    Figure 9.  Active and reactive power capacity of an inverter.

    A proposed power factor controller is shown below in Figure 10. This intuitive controller works by detecting a decrease in the PCC power factor below a specific limit. Consequently, it commands the inverter to decrease its power factor by an increment (e.g., 0.01).

    Figure 10.  Suggested PV block diagram of power factor controller.

    If the PCC power factor increases above the limit, the controller goes back by increasing the inverter power factor by the same increment. Figure 11, shown below, shows how the injection of pure active power comes with a decrease in the PCC power factor. Thus, the controller senses the limit of 0.95 and sends a signal to the inverter to decrease the power factor by 0.01. As a result, the total power factor experiences an increase as reactive power is injected into the grid. Using such a controller could help in more than one way. First, it adds an element of flexibility with load and generation intermittency. Second, it serves as an economic optimization tool, where customers can avoid penalties concerning excessive reactive power consumption. Moreover, it maximizes the active power generation when there is no need for a leading power factor. To elaborate on the latter, Figure 12 shows how a fixed power factor can waste much energy, especially at times other than the peak.

    Figure 11.  Performance of the suggested power factor controller.
    Figure 12.  PF influence on output energy from the PV system.

    This refers to utilizing the suggested power factor controller could encourage municipalities and grid operators to consider such controllers as a superior way to overcome power factor compensation. Such controllers can be found commercially with various construction. For example, the power factor monitoring and control system has been used in several solar power plants in Palestine, with the Skytron system being used for the first time in a solar power plant with a peak capacity of 992 kW on the roof of the National Aluminum and Profile Company (NAPCO) factory in 2019. This technique is used in two ground-based solar power facilities in the Palestinian territories of Birzeit and Ya'bad [34,35]. Many aspects of the station's performance, particularly the power factor, are controlled by the device, which is constantly working to change the value of the inverters to ensure the highest production and the highest efficiency of the station without affecting the power factor the connection point in question. The figure below shows how such a controller alters the power factor of the PV system. These data are taken from a 1 MW PV plant in Birzeit, Palestine. It is evident how at low generation, time step 35, the inverter increases its power factor since there is less need for reactive power.

    Figure 13.  PCC power factor behavior against PV power factor.

    When it comes to distributed generation (DG) using renewable energy (RE) sources, there are several obstacles to overcome, the most prominent of which is the impact of intermittency, as well as technological concerns deriving from grid connections [36]. The photovoltaic array, for example, feeds electrical energy directly into the electrical grid (also known as grid-tied systems), such as a solar-powered system [37]. Due to the unpredictability of solar radiation, this kind of system is regarded as an unstable energy source. Although challenging to forecast, the performance of these systems is vitally significant in many associated aspects such as system sizing and control [38]. Because the integration of distributed generation into a power system is not considered in the initial network design, certain technical consequences of PV integration into a power system might occur [39]. Moreover, various factors can be analyzed and studied as the impact of connecting PV plants to the national grid, such as the evaluation of the harmonics generated by the PV inverter and the influence of these harmonics on the current harmonic spectrum of the current injected by the PV system at PCC bus [40].

    The increased penetration of PV systems in Palestine requires an in-depth study to consider their impact on the national grid. Overall grid power factor comes as one of the essential criteria to be considered when any grid impact study is performed. This paper's extensive literature review of the power factor importance and its side effects was delivered. Besides, a lookup table was developed to help grid operators choose the proper power factor for any PV system added to the grid. All data used in this study are actual data to increase the validity of the findings. It was also found that an auxiliary power fac-tor controller can be even more helpful and less stressful for designers to improve power factor.

    The author would like to thank the Solar Energy Research Institute, UKM for the lab facilities. This research was funded by Universiti Kebangsaan Malaysia (UKM), research grant Program Translational MRUN Rakan-RU-2019-001/4.

    The authors declare no conflict of interest



    [1] M. Portegies, P. Koudstaal, M. Ikram, Cerebrovascular disease, Handb. Clin. Neurol., 138 (2016), 239–261. https://doi.org/10.1016/B978-0-12-802973-2.00014-8 doi: 10.1016/B978-0-12-802973-2.00014-8
    [2] X. Tong, Q. Yang, M. D. Ritchey, M. G. George, S. L. Jackson, C. Gillespie, et al., The burden of cerebrovascular disease in the United States, Prev. Chronic. Dis., 16 (2019), 180411. https://doi.org/10.5888/pcd16.180411 doi: 10.5888/pcd16.180411
    [3] S. Yoshimura, N. Sakai, H. Yamagami, K. Uchida, M. Beppu, K. Toyoda, et al., Endovascular therapy for acute stroke with a large ischemic region, N. Engl. J. Med., 386 (2022), 1303–1313. https://doi.org/10.1056/NEJMoa2118191 doi: 10.1056/NEJMoa2118191
    [4] Q. Z. Tuo, S. T. Zhang, P. Lei, Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications, Med. Res. Rev., 42 (2022), 259–305. https://doi.org/10.1002/med.21817 doi: 10.1002/med.21817
    [5] K. N. Kadyrovich, S. K. Erkinovich, K. M. Ilhomovna, Microscopic examination of postcapillary cerebral venues in hemorrhagic stroke, Am. J. Med. Sci. Pharm. Res., 3 (2021), 69–73. https://doi.org/10.37547/TAJMSPR/Volume03Issue08-11 doi: 10.37547/TAJMSPR/Volume03Issue08-11
    [6] M. L. Osgood, Aneurysmal subarachnoid hemorrhage: Review of the pathophysiology and management strategies, Curr. Neurol. Neurosci. Rep., 21 (2021), 1–11. https://doi.org/10.1007/s11910-021-01136-9 doi: 10.1007/s11910-021-01136-9
    [7] S. N. Neifert, E. K. Chapman, M. L. Martini, W. H. Shuman, A. J. Schupper, E. K. Oermann, et al., Aneurysmal subarachnoid hemorrhage: The last decade, Transl. Stroke Res., 12 (2021), 428–446. https://doi.org/10.1007/s12975-020-00867-0 doi: 10.1007/s12975-020-00867-0
    [8] W. S. Dodd, D. Laurent, A. S. Dumont, D. M. Hasan, P. M. Jabbour, R. M. Starke, et al., Pathophysiology of delayed cerebral ischemia after subarachnoid hemorrhage: A review, J. Am. Heart Assoc., 10 (2021), e021845. https://doi.org/10.1161/jaha.121.021845 doi: 10.1161/jaha.121.021845
    [9] I. Daghals, M. Sargurupremraj, R. Danning, P. Gormley, R. Malik, P. Amouyel, et al., Migraine, stroke, and cervical arterial dissection: Shared genetics for a triad of brain disorders with vascular involvement, Neurol. Genet., 8 (2022), e653. https://doi.org/10.1212/nxg.0000000000000653 doi: 10.1212/nxg.0000000000000653
    [10] M. Marciniec, K. Sapko, M. Kulczyński, S. Popek-Marciniec, A. Szczepańska-Szerej, K. Rejdak, Non-traumatic cervical artery dissection and ischemic stroke: A narrative review of recent research, Clin. Neurol. Neurosurg., 187 (2019), 105561. https://doi.org/10.1016/j.clineuro.2019.105561 doi: 10.1016/j.clineuro.2019.105561
    [11] M. M. Ruchoux, C. A. Maurage, CADASIL: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, J. Neuropathol. Exp. Neurol., 56 (1997), 947–964. https://doi.org/10.1097/00005072-199709000-00001 doi: 10.1097/00005072-199709000-00001
    [12] M. Bousser, E. Tournier-Lasserve, Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: From stroke to vessel wall physiology, J. Neurol. Neurosurg. Psychiatry, 70 (2001), 285–287. https://doi.org/10.1136/jnnp.70.3.285 doi: 10.1136/jnnp.70.3.285
    [13] E. Navarro, F. Díaz, L. Muñoz, S. Giménez-Roldán, Dominant autosomal cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL): A review, Neurologia, 17 (2002), 410–417.
    [14] L. Prado, C. Han, S. P. Oh, H. Su, Recent advances in basic research for brain arteriovenous malformation, Int. J. Mol. Sci., 20 (2019), 5324. https://doi.org/10.3390/ijms20215324 doi: 10.3390/ijms20215324
    [15] P. Pan, S. Weinsheimer, D. Cooke, E. Winkler, A. Abla, H. Kim, et al., Review of treatment and therapeutic targets in brain arteriovenous malformation, J. Cereb. Blood Flow Metab., 41 (2021), 3141–3156. https://doi.org/10.1177/0271678x211026771 doi: 10.1177/0271678x211026771
    [16] S. S. Shaligram, E. Winkler, D. Cooke, H. Su, Risk factors for hemorrhage of brain arteriovenous malformation, CNS Neurosci. Ther., 25 (2019), 1085–1095. https://doi.org/10.1111/cns.13200 doi: 10.1111/cns.13200
    [17] M. Capecchi, M. Abbattista, I. Martinelli, Cerebral venous sinus thrombosis, J. Thromb. Haemostasis, 76 (2018), 12–15. https://doi.org/10.1111/jth.14210 doi: 10.1111/jth.14210
    [18] G. Sébire, B. Tabarki, D. E. Saunders, I. Leroy, R. Liesner, C. Saint-Martin, et al., Cerebral venous sinus thrombosis in children: Risk factors, presentation, diagnosis and outcome, Brain, 128 (2005), 477–489. https://doi.org/10.1093/brain/awh412 doi: 10.1093/brain/awh412
    [19] J. M. Ferro, P. Canhão, Cerebral venous sinus thrombosis: Update on diagnosis and management, Curr. Cardiol. Rep., 16 (2014), 523. https://doi.org/10.1007/s11886-014-0523-2 doi: 10.1007/s11886-014-0523-2
    [20] H. Zhang, L. Zheng, L. Feng, Epidemiology, diagnosis and treatment of moyamoya disease, Exp. Ther. Med., 17 (2019), 1977–1984. https://doi.org/10.3892/etm.2019.7198 doi: 10.3892/etm.2019.7198
    [21] J. Li, M. Jin, X. Sun, J. Li, Y. Liu, Y. Xi, et al., Imaging of moyamoya disease and moyamoya syndrome: Current status, J. Comput. Assist. Tomogr., 43 (2019), 257–263. https://doi.org/10.1097/rct.0000000000000834 doi: 10.1097/rct.0000000000000834
    [22] S. Shang, D. Zhou, J. Ya, S. Li, Q. Yang, Y. Ding, et al., Progress in moyamoya disease, Neurosurg. Rev., 43 (2020), 371–382. https://doi.org/10.1007/s10143-018-0994-5 doi: 10.1007/s10143-018-0994-5
    [23] C. Esenwa, J. Gutierrez, Secondary stroke prevention: Challenges and solutions, Vasc. Health Risk Manag., 11 (2015), 437–450. https://doi.org/10.2147/vhrm.S63791 doi: 10.2147/vhrm.S63791
    [24] V. L. Feigin, M. H. Forouzanfar, R. Krishnamurthi, G. A. Mensah, M. Connor, D. A. Bennett, et al., Global and regional burden of stroke during 1990–2010: Findings from the global burden of disease study 2010, Lancet, 383 (2014), 245–254. https://doi.org/10.1016/s0140-6736(13)61953-4 doi: 10.1016/s0140-6736(13)61953-4
    [25] I. Nagy, D. Fabó, Clinical neurophysiological methods in diagnosis and treatment of cerebrovascular diseases, Ideggyogy. Sz., 71 (2018), 7–14. https://doi.org/10.18071/isz.71.0007 doi: 10.18071/isz.71.0007
    [26] J. A. Barios, S. Ezquerro, A. Bertomeu-Motos, J. M. Catalan, J. M. Sanchez-Aparicio, L. Donis-Barber, et al., Movement-related EEG oscillations of contralesional hemisphere discloses compensation mechanisms of severely affected motor chronic stroke patients, Int. J. Neural. Syst., 31 (2021), 2150053. https://doi.org/10.1142/s0129065721500532 doi: 10.1142/s0129065721500532
    [27] S. Shaban, B. Huasen, A. Haridas, M. Killingsworth, J. Worthington, P. Jabbour, et al., Digital subtraction angiography in cerebrovascular disease: Current practice and perspectives on diagnosis, acute treatment and prognosis, Acta Neurol. Belg., 122 (2022), 763–780. https://doi.org/10.1007/s13760-021-01805-z doi: 10.1007/s13760-021-01805-z
    [28] C. C. Young, R. H. Bonow, G. Barros, M. Mossa-Basha, L. J. Kim, M. R. Levitt, Magnetic resonance vessel wall imaging in cerebrovascular diseases, Neurosurg. Focus, 47 (2019), E4. https://doi.org/10.3171/2019.9.Focus19599 doi: 10.3171/2019.9.Focus19599
    [29] S. F. Xiang, J. T. Li, S. J. Yang, F. F. Ding, W. W. Wang, S. Huo, et al., Whole-brain volume CT angiography can effectively detect early ischemic cerebrovascular diseases, Curr. Med. Imaging, 18 (2022), 731–738. https://doi.org/10.2174/1573405617666211206091831 doi: 10.2174/1573405617666211206091831
    [30] K. Taneja, H. Lu, B. G. Welch, B. P. Thomas, M. Pinho, D. Lin, et al., Evaluation of cerebrovascular reserve in patients with cerebrovascular diseases using resting-state MRI: A feasibility study, Magn. Reson. Imaging, 59 (2019), 46–52. https://doi.org/10.1016/j.mri.2019.03.003 doi: 10.1016/j.mri.2019.03.003
    [31] L. Carnevale, G. Lembo, Innovative MRI techniques in neuroimaging approaches for cerebrovascular diseases and vascular cognitive impairment, Int. J. Mol. Sci., 20 (2019), 2656. https://doi.org/10.3390/ijms20112656 doi: 10.3390/ijms20112656
    [32] J. S. Minhas, R. B. Panerai, G. Ghaly, P. Divall, T. G. Robinson, Cerebral autoregulation in hemorrhagic stroke: A systematic review and meta-analysis of transcranial Doppler ultrasonography studies, J. Clin. Ultrasound, 47 (2019), 14–21. https://doi.org/10.1002/jcu.22645 doi: 10.1002/jcu.22645
    [33] S. Sharma, R. J. Lubrica, M. Song, R. Vandse, W. Boling, P. Pillai, The role of transcranial Doppler in cerebral vasospasm: A literature review, Subarachnoid Hemorrh., 127 (2020), 201–205. https://doi.org/10.1007/978-3-030-04615-6_32 doi: 10.1007/978-3-030-04615-6_32
    [34] N. Fatima, A. Shuaib, T. S. Chughtai, A. Ayyad, M. Saqqur, The role of transcranial Doppler in traumatic brain injury: A Systemic review and Meta-analysis, Asian J. Neurosurg., 14 (2019), 626–633. https://doi.org/10.4103/ajns.AJNS_42_19 doi: 10.4103/ajns.AJNS_42_19
    [35] V. K. Sharma, K. S. Wong, A. V. Alexandrov, Transcranial Doppler, Front. Neurol. Neurosci., 40 (2016), 124–140. https://doi.org/10.1159/000448309 doi: 10.1159/000448309
    [36] C. C. Bishop, S. Powell, D. Rutt, N. L. Browse, Transcranial Doppler measurement of middle cerebral artery blood flow velocity: A validation study, Stroke, 17 (1986), 913–915. https://doi.org/10.1161/01.str.17.5.913 doi: 10.1161/01.str.17.5.913
    [37] S. Purkayastha, F. Sorond, Transcranial Doppler ultrasound: Technique and application, Semin. Neurol., 32 (2012), 411–420. https://doi.org/10.1055/s-0032-1331812 doi: 10.1055/s-0032-1331812
    [38] C. K. Willie, F. L. Colino, D. M. Bailey, Y. C. Tzeng, G. Binsted, L. W. Jones, et al., Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function, J. Neurosci. Methods., 196 (2011), 221–237. https://doi.org/10.1016/j.jneumeth.2011.01.011 doi: 10.1016/j.jneumeth.2011.01.011
    [39] G. Tsivgoulis, A. V. Alexandrov, M. A. Sloan, Advances in transcranial Doppler ultrasonography, Curr. Neurol. Neurosci. Rep., 9 (2009), 46–54. https://doi.org/10.1007/s11910-009-0008-7 doi: 10.1007/s11910-009-0008-7
    [40] F. A. Rasulo, E. De Peri, A. Lavinio, Transcranial Doppler ultrasonography in intensive care, Eur. J. Anaesthesiol. Suppl., 42 (2008), 167–173. https://doi.org/10.1017/s0265021507003341 doi: 10.1017/s0265021507003341
    [41] T. Montrief, S. Alerhand, C. Jewell, J. Scott, Incorporation of transcranial Doppler into the ED for the neurocritical care patient, Am. J. Emerg. Med., 37 (2019), 1144–1152. https://doi.org/10.1016/j.ajem.2019.03.003 doi: 10.1016/j.ajem.2019.03.003
    [42] J. H. Fetzer, What is artificial intelligence, in Artificial Intelligence: Its Scope and Limits (eds J. H. Fetzer), (1990), 3–27. https://doi.org/10.1007/978-94-009-1900-6_1
    [43] M. Haenlein, A. Kaplan, A brief history of artificial intelligence: On the past, present, and future of artificial intelligence, Calif. Manage. Rev., 61 (2019), 5–14. https://doi.org/10.1177/0008125619864925 doi: 10.1177/0008125619864925
    [44] C. Zhang, Y. Lu, Study on artificial intelligence: The state of the art and future prospects, J. Ind. Inf. Integr., 23 (2021), 100224. https://doi.org/10.1016/j.jii.2021.100224 doi: 10.1016/j.jii.2021.100224
    [45] Y. K. Chan, Y. F. Chen, T. Pham, W. Chang, M. Y. Hsieh, Artificial intelligence in medical applications, J. Healthcare Eng., 2018 (2018), 1–2. https://doi.org/10.1155/2018/4827875 doi: 10.1155/2018/4827875
    [46] J. Stewart, P. Sprivulis, G. Dwivedi, Artificial intelligence and machine learning in emergency medicine, Emerg. Med. Australas., 30 (2018), 870–874. https://doi.org/10.1111/1742-6723.13145 doi: 10.1111/1742-6723.13145
    [47] A. Kirubarajan, A. Taher, S. Khan, S. Masood, Artificial intelligence in emergency medicine: A scoping review, J. Am. Coll. Emerg. Phys. Open., 1 (2020), 1691–1702. https://doi.org/10.1002/emp2.12277 doi: 10.1002/emp2.12277
    [48] Y. Berlyand, A. S. Raja, S. C. Dorner, A. M. Prabhakar, J. D. Sonis, R. V. Gottumukkala, et al., How artificial intelligence could transform emergency department operations, Am. Jo. Emerg. Med., 36 (2018), 1515–1517. https://doi.org/10.1016/j.ajem.2018.01.017 doi: 10.1016/j.ajem.2018.01.017
    [49] A. J. Myrden, A. Kushki, E. Sejdić, A. M. Guerguerian, T. Chau, A brain-computer interface based on bilateral transcranial Doppler ultrasound, PLoS One, 6 (2011), e24170. https://doi.org/10.1371/journal.pone.0024170 doi: 10.1371/journal.pone.0024170
    [50] N. Birbaumer, Breaking the silence: Brain-computer interfaces (BCI) for communication and motor control, Psychophysiology, 43 (2006), 517–532. https://doi.org/10.1111/j.1469-8986.2006.00456.x doi: 10.1111/j.1469-8986.2006.00456.x
    [51] H. Uğuz, A. Öztürk, R. Saraçoğlu, A. Arslan, A biomedical system based on fuzzy discrete hidden Markov model for the diagnosis of the brain diseases, Expert Syst. Appl., 35 (2008), 1104–1114. https://doi.org/10.1016/j.eswa.2007.08.006 doi: 10.1016/j.eswa.2007.08.006
    [52] I. Güler, F. Hardalaç, M. Kaymaz, Comparison of FFT and adaptive ARMA methods in transcranial Doppler signals recorded from the cerebral vessels, Comput. Biol. Med., 32 (2002), 445–453. https://doi.org/10.1016/s0010-4825(02)00036-7 doi: 10.1016/s0010-4825(02)00036-7
    [53] N. Karaboga, F. Latifoglu, Elimination of noise on transcranial Doppler signal using ⅡR filters designed with artificial bee colony—ABC-algorithm, Digital Signal Process., 23 (2013), 1051–1058. https://doi.org/10.1016/j.dsp.2012.09.015 doi: 10.1016/j.dsp.2012.09.015
    [54] T. Koza, S. Koçkana, N. Karaboğa, F. Latifoğlu, SSA analysis of noise eliminated transcranial doppler signals with iIR filters, in 2015 23nd Signal Processing and Communications Applications Conference (SIU), (2015), 2021–2024. https://doi.org/10.1109/SIU.2015.7130262
    [55] Y. J. Mei, R. T. Hu, J. Lin, H. Y. Xu, L. Y. Wu, H. P. Li, et al., Diagnosis of middle cerebral artery stenosis using transcranial Doppler images based on convolutional neural network, World Neurosurg., 161 (2022), e118–e125. https://doi.org/10.1016/j.wneu.2022.01.068 doi: 10.1016/j.wneu.2022.01.068
    [56] A. Baig, C. Manion, V. Iyer, W. Khawar, B. Donnelly, A. Monteiro, et al., E-142 robotic transcranial doppler with artificial intelligence to identify cerebral emboli during transcatheter aortic valve replacement - a novel neuromonitoring tool, J. NeuroInterventional Surg., 14 (2022), A152. https://doi.org/10.1136/neurintsurg-2022-SNIS.253 doi: 10.1136/neurintsurg-2022-SNIS.253
    [57] S. Esmaeeli, C. M. Hrdlicka, A. Brenes Bastos, J. Wang, S. Gomez-Paz, K. A. Hanafy, et al., Robotically assisted transcranial Doppler with artificial intelligence for assessment of cerebral vasospasm after subarachnoid hemorrhage, J. Neurocrit. Care, 13 (2020), 32–40. https://doi.org/10.18700/jnc.200002 doi: 10.18700/jnc.200002
    [58] H. White, B. Venkatesh, Applications of transcranial Doppler in the ICU: A review, Intensive Care Med., 32 (2006), 981–994. https://doi.org/10.1007/s00134-006-0173-y doi: 10.1007/s00134-006-0173-y
    [59] Y. Pan, W. Wan, M. Xiang, Y. Guan, Transcranial Doppler ultrasonography as a diagnostic tool for cerebrovascular disorders, Front. Hum. Neurosci., 16 (2022), 841809. https://doi.org/10.3389/fnhum.2022.841809 doi: 10.3389/fnhum.2022.841809
    [60] J. C. Granry, Transcranial Doppler in anesthesia and intensive care, Ann. Fr. Anesth. Reanim., 10 (1991), 127–136. https://doi.org/10.1016/s0750-7658(05)80453-8 doi: 10.1016/s0750-7658(05)80453-8
    [61] M. P. Spencer, D. Whisler, Transorbital Doppler diagnosis of intracranial arterial stenosis, Stroke, 17 (1986), 916–921. https://doi.org/10.1161/01.str.17.5.916 doi: 10.1161/01.str.17.5.916
    [62] L. Thomassen, U. Waje-Andreassen, H. Naess, J. Aarseth, D. Russell, Doppler ultrasound and clinical findings in patients with acute ischemic stroke treated with intravenous thrombolysis, Eur. J. Neurol., 12 (2005), 462–465. https://doi.org/10.1111/j.1468-1331.2005.01008.x doi: 10.1111/j.1468-1331.2005.01008.x
    [63] J. Allendoerfer, M. Goertler, G. M. von Reutern, Prognostic relevance of ultra-early doppler sonography in acute ischaemic stroke: A prospective multicentre study, Lancet Neurol., 5 (2006), 835–840. https://doi.org/10.1016/s1474-4422(06)70551-8 doi: 10.1016/s1474-4422(06)70551-8
    [64] A. Mattioni, S. Cenciarelli, P. Eusebi, M. Brazzelli, T. Mazzoli, M. Del Sette, et al., Transcranial Doppler sonography for detecting stenosis or occlusion of intracranial arteries in people with acute ischaemic stroke, Cochrane Database Syst. Rev., 2 (2020), Cd010722. https://doi.org/10.1002/14651858.CD010722.pub2 doi: 10.1002/14651858.CD010722.pub2
    [65] N. Samagh, H. Bhagat, K. Jangra, Monitoring cerebral vasospasm: How much can we rely on transcranial Doppler, J. Anaesthesiol. Clin. Pharmacol., 35 (2019), 12–18. https://doi.org/10.4103/joacp.JOACP_192_17 doi: 10.4103/joacp.JOACP_192_17
    [66] R. Aaslid, Transcranial Doppler assessment of cerebral vasospasm, Eur. J. Ultrasound, 16 (2002), 3–10. https://doi.org/10.1016/s0929-8266(02)00045-9 doi: 10.1016/s0929-8266(02)00045-9
    [67] D. D. Li, J. Y. Chang, C. X. Zhou, J. B. Cui, Clinical diagnosis of cerebral vasospasm after subarachnoid hemorrhage by using transcranial Doppler sonography, Eur. Rev. Med. Pharmacol. Sci., 22 (2018), 2029–2035. https://doi.org/10.26355/eurrev_201804_14732 doi: 10.26355/eurrev_201804_14732
    [68] C. E. Scherle Matamoros, E. A. Samaniego, K. Sam, J. A. Roa, J. P. Nellar, D. R. Rodríguez, Prediction of symptomatic vasospasm in patients with aneurysmal subarachnoid hemorrhage using early transcranial Doppler, J. Vasc. Interv. Neurol., 11 (2020), 19–26.
    [69] R. Behrouz, The rise and fall of transcranial Doppler ultrasonography for the diagnosis of vasospasm in aneurysmal subarachnoid hemorrhage, J. Neurosurg. Anesthesiol., 31 (2019), 79–80. https://doi.org/10.1097/ana.0000000000000490 doi: 10.1097/ana.0000000000000490
    [70] B. P. D. Inusa, L. Sainati, C. MacMahon, R. Colombatti, M. Casale, S. Perrotta, et al., An educational study promoting the delivery of transcranial Doppler ultrasound screening in paediatric sickle cell disease: A european multi-centre perspective, J. Clin. Med., 9 (2019), 44. https://doi.org/10.3390/jcm9010044 doi: 10.3390/jcm9010044
    [71] J. Kanter, S. Phillips, A. M. Schlenz, M. Mueller, M. Dooley, L. Sirline, et al., Transcranial doppler screening in a current cohort of children with sickle cell anemia: Results from the displace study, J. Pediatr. Hematol. Oncol., 43 (2021), e1062–e1068. https://doi.org/10.1097/mph.0000000000002103 doi: 10.1097/mph.0000000000002103
    [72] S. Thurn, K. Kleinschmidt, I. Kovacic, C. Wendl, R. A. Linker, S. Corbacioglu, et al., Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease, Neurol. Res. Pract., 4 (2022), 12. https://doi.org/10.1186/s42466-022-00175-y doi: 10.1186/s42466-022-00175-y
    [73] A. Pedicelli, M. Bartocci, E. Lozupone, F. D'Argento, A. Alexandre, G. Garignano, et al., The role of cervical color Doppler ultrasound in the diagnosis of brain death, Neuroradiology, 61 (2019), 137–145. https://doi.org/10.1007/s00234-018-2111-4 doi: 10.1007/s00234-018-2111-4
    [74] Y. Zurynski, N. Dorsch, I. Pearson, R. Choong, Transcranial Doppler ultrasound in brain death: Experience in 140 patients, Neurol. Res., 13 (1991), 248–252. https://doi.org/10.1080/01616412.1991.11740000 doi: 10.1080/01616412.1991.11740000
    [75] D. Escudero, J. Otero, B. Quindós, L. Viña, Transcranial Doppler ultrasound in the diagnosis of brain death. Is it useful or does it delay the diagnosis, Med. Intensiva, 39 (2015), 244–250. https://doi.org/10.1016/j.medin.2014.11.005 doi: 10.1016/j.medin.2014.11.005
    [76] D. Grosset, Aneurysm re-rupture: Doppler evidence of first phase vasospasm, J. Neurol. Neurosurg. Psychiatry, 53 (1990), 361. https://doi.org/10.1136/jnnp.53.4.361-b doi: 10.1136/jnnp.53.4.361-b
    [77] J. De Léan, N. Thomas, Neurological Complications of Pregnancy Advances in Neurology, VOLUME 64, 1993, Edited by O. Devinsky, E. Feldman and B. Hainline, Published by Raven Press, 286 pages, $C117.00, Can. J. Neurol. Sci., 24 (1977), 88. https://doi.org/10.1017/S031716710002120X
    [78] R. A. Purdy, Neurology in Clinical Practice, VOLUME 1 & 2, 1995, Edited by W. G. Bradley, R. B. Daroff, G. M. Fenichel, C. D. Marsden, Published by Butterworth-Heinemann, 3264 pages, $C439.00, Can. J. Neurol. Sci., 24 (1977), 88–89. https://doi.org/10.1017/S0317167100021223
    [79] R. Aaslid, T. M. Markwalder, H. Nornes, Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries, J. Neurosurg., 57 (1982), 769–774. https://doi.org/10.3171/jns.1982.57.6.0769 doi: 10.3171/jns.1982.57.6.0769
    [80] A. H. Ropper, S. M. Kehne, L. Wechsler, Transcranial Doppler in brain death, Neurology, 37 (1987), 1733–1733. https://doi.org/10.1212/wnl.37.11.1733 doi: 10.1212/wnl.37.11.1733
    [81] N. K. Altinbas, E. Ustuner, H. Ozcan, S. Bilgic, T. Sancak, E. Dusunceli, Effect of carotid artery stenting on ophthalmic artery flow patterns, J. Ultrasound Med., 33 (2014), 629–638. https://doi.org/10.7863/ultra.33.4.629 doi: 10.7863/ultra.33.4.629
    [82] J. Sun, Y. Liu, J. Zhang, X. Chen, Z. Lin, S. Nie, et al., Electroacupuncture improves cerebral vasospasm and functional outcome of patients with aneurysmal subarachnoid hemorrhage, Front. Neurosci., 12 (2018), 724. https://doi.org/10.3389/fnins.2018.00724 doi: 10.3389/fnins.2018.00724
    [83] D. B. Berry, E. K. Englund, S. Chen, L. R. Frank, S. R. Ward, Medical imaging of tissue engineering and regenerative medicine constructs, Biomater. Sci., 9 (2021), 301–314. https://doi.org/10.1039/d0bm00705f doi: 10.1039/d0bm00705f
    [84] O. M. Pinillos, C. N. Rodríguez, R. Hakimi, Transcranial Doppler ultrasound pulsatility index: Utility and clinical interpretation, in Neurosonology in Critical Care: Monitoring the Neurological Impact of the Critical Pathology (eds C. N. Rodríguez and C. Baracchini), (2022), 357–376. https://doi.org/10.1007/978-3-030-81419-9_21
    [85] N. G. Rainov, J. B. Weise, W. Burkert, Transcranial Doppler sonography in adult hydrocephalic patients, Neurosurg. Rev., 23 (2000), 34–38. https://doi.org/10.1007/s101430050029 doi: 10.1007/s101430050029
    [86] L. Wang, Y. Xing, Y. Li, K. Han, J. Chen, Evaluation of flow velocity in unilateral middle cerebral artery stenosis by Transcranial Doppler, Cell Biochem. Biophys., 70 (2014), 823–830. https://doi.org/10.1007/s12013-014-9986-4 doi: 10.1007/s12013-014-9986-4
    [87] M. B. McCarville, Comparison of duplex and nonduplex transcranial Doppler ultrasonography, Ultrasound Q, 24 (2008), 167–171. https://doi.org/10.1097/RUQ.0b013e3181862b67 doi: 10.1097/RUQ.0b013e3181862b67
    [88] L. Duan, L. D. Xu, Business Intelligence for Enterprise Systems: A Survey, IEEE Trans. Ind. Inf., 8 (2012), 679–687. https://doi.org/10.1109/tii.2012.2188804 doi: 10.1109/tii.2012.2188804
    [89] Y. Lu, L. D. Xu, Internet of things (IoT) cybersecurity research: A review of current research topics, IEEE Int. Things J., 6 (2019), 2103–2115. https://doi.org/10.1109/jiot.2018.2869847 doi: 10.1109/jiot.2018.2869847
    [90] P. Hamet, J. Tremblay, Artificial intelligence in medicine, Metabolism, 69 (2017), S36–S40. https://doi.org/10.1016/j.metabol.2017.01.011 doi: 10.1016/j.metabol.2017.01.011
    [91] V. Kaul, S. Enslin, S. A. Gross, History of artificial intelligence in medicine, Gastrointest. Endosc., 92 (2020), 807–812. https://doi.org/10.1016/j.gie.2020.06.040 doi: 10.1016/j.gie.2020.06.040
    [92] E. H. Shortliffe, R. Davis, S. G. Axline, B. G. Buchanan, C. C. Green, S. N. Cohen, Computer-based consultations in clinical therapeutics: Explanation and rule acquisition capabilities of the MYCIN system, Comput. Biomed. Res., 8 (1975), 303–320. https://doi.org/10.1016/0010-4809(75)90009-9 doi: 10.1016/0010-4809(75)90009-9
    [93] B. G. Buchanan, E. A. Feigenbaum, The stanford heuristic programming project: Goals and activities, AI Mag., 1 (2017), 25. https://doi.org/10.1609/aimag.v1i1.89 doi: 10.1609/aimag.v1i1.89
    [94] S. M. Weiss, C. A. Kulikowski, S. Amarel, A. Safir, A model-based method for computer-aided medical decision-making, Artif. Intell., 11 (1978), 145–172. https://doi.org/10.1016/0004-3702(78)90015-2 doi: 10.1016/0004-3702(78)90015-2
    [95] E. Strickland, IBM Watson, heal thyself: How IBM overpromised and underdelivered on AI health care, IEEE Spectr., 56 (2019), 24–31. https://doi.org/10.1109/mspec.2019.8678513 doi: 10.1109/mspec.2019.8678513
    [96] M. Christ, F. Grossmann, D. Winter, R. Bingisser, E. Platz, Modern triage in the emergency department, Dtsch. Arztebl. Int., 107 (2010), 892–898. https://doi.org/10.3238/arztebl.2010.0892 doi: 10.3238/arztebl.2010.0892
    [97] C. I. Price, L. Shaw, S. Islam, M. Javanbakht, A. Watkins, P. McMeekin, et al., Effect of an enhanced paramedic acute stroke treatment assessment on thrombolysis delivery during emergency stroke care: A cluster randomized clinical trial, JAMA Neurol., 77 (2020), 840–848. https://doi.org/10.1001/jamaneurol.2020.0611 doi: 10.1001/jamaneurol.2020.0611
    [98] M. Kanglie, S. Bipat, I. A. H. van den Berk, T. S. R. van Engelen, M. G. W. Dijkgraaf, J. M. Prins, et al., OPTimal IMAging strategy in patients suspected of non-traumatic pulmonary disease at the emergency department: Chest X-ray or ultra-low-dose chest CT (OPTIMACT) trial-statistical analysis plan, Trials, 21 (2020), 407. https://doi.org/10.1186/s13063-020-04343-w doi: 10.1186/s13063-020-04343-w
    [99] G. Vingerhoets, N. Stroobant, Lateralization of cerebral blood flow velocity changes during cognitive tasks. A simultaneous bilateral transcranial Doppler study, Stroke, 30 (1999), 2152–2158. https://doi.org/10.1161/01.str.30.10.2152 doi: 10.1161/01.str.30.10.2152
    [100] T. Wessels, J. U. Harrer, C. Jacke, U. Janssens, C. Klö tzsch, The prognostic value of early transcranial Doppler ultrasound following cardiopulmonary resuscitation, Ultrasound Med. Biol., 32 (2006), 1845–1851. https://doi.org/10.1016/j.ultrasmedbio.2006.06.023 doi: 10.1016/j.ultrasmedbio.2006.06.023
    [101] A. Myrden, A. Kushki, E. Sejdić, T. Chau, Towards increased data transmission rate for a three-class metabolic brain-computer interface based on transcranial Doppler ultrasound, Neurosci. Lett., 528 (2012), 99–103. https://doi.org/10.1016/j.neulet.2012.09.030 doi: 10.1016/j.neulet.2012.09.030
    [102] A. Goyal, A. A. Samadani, A. M. Guerguerian, T. Chau, An online three-class Transcranial Doppler ultrasound brain computer interface, Neurosci. Res., 107 (2016), 47–56. https://doi.org/10.1016/j.neures.2015.12.013 doi: 10.1016/j.neures.2015.12.013
    [103] A. Khalaf, M. Sybeldon, E. Sejdic, M. Akcakaya, A brain-computer interface based on functional transcranial doppler ultrasound using wavelet transform and support vector machines, J. Neurosci. Methods, 293 (2018), 174–182. https://doi.org/10.1016/j.jneumeth.2017.10.003 doi: 10.1016/j.jneumeth.2017.10.003
    [104] S. Serhatlioğlu, F. Hardalaç, I. Güler, Classification of transcranial Doppler signals using artificial neural network, J. Med. Syst., 27 (2003), 205–214. https://doi.org/10.1023/a:1021821229512 doi: 10.1023/a:1021821229512
    [105] A. Ozturk, A. Arslan, F. Hardalac, Comparison of neuro-fuzzy systems for classification of transcranial Doppler signals with their chaotic invariant measures, Expert Syst. Appl., 34 (2008), 1044–1055. https://doi.org/10.1016/j.eswa.2006.12.006 doi: 10.1016/j.eswa.2006.12.006
    [106] H. Uğuz, A hybrid system based on information gain and principal component analysis for the classification of transcranial Doppler signals, Comput. Methods Prog. Biomed., 107 (2011), 598–609. https://doi.org/10.1016/j.cmpb.2011.03.013 doi: 10.1016/j.cmpb.2011.03.013
    [107] H. Uğuz, A. Arslan, A new approach based on discrete hidden Markov model using Rocchio algorithm for the diagnosis of the brain diseases, Digital Signal Process., 20 (2010), 923–934. https://doi.org/10.1016/j.dsp.2009.11.001 doi: 10.1016/j.dsp.2009.11.001
    [108] M. Seera, C. P. Lim, K. S. Tan, W. S. Liew, Classification of transcranial Doppler signals using individual and ensemble recurrent neural networks, Neurocomputing, 249 (2017), 337–344. https://doi.org/10.1016/j.neucom.2016.05.11 doi: 10.1016/j.neucom.2016.05.11
    [109] N. Karaboga, F. Latifoglu, Adaptive filtering noisy transcranial Doppler signal by using artificial bee colony algorithm, Eng. Appl. Artif. Intell., 26 (2013), 677–684. https://doi.org/10.1016/j.engappai.2012.10.011 doi: 10.1016/j.engappai.2012.10.011
    [110] N. Karaboga, F. Latifoglu, T. Koza, SSA analysis of transcranial Doppler signal using ⅡR filters designed with ABC algorithm, Curr. Opin. Biotechnol., 22 (2011), 5. https://doi.org/10.1016/j.copbio.2011.05.159 doi: 10.1016/j.copbio.2011.05.159
    [111] B. Kamişlıoğlu, T. Koza, S. Koçkanat, N. Karaboğa, Noise cancellation on mitral valve Doppler signal with ⅡR digital filter using harmony search algorithm, in 2013 IEEE INISTA, (2013), 1–5. https://doi.org/10.1109/INISTA.2013.6577620
    [112] K. Clare, A. Stein, N. Damodara, E. Feldstein, H. Alshammari, S. Ali, et al., Safety and efficacy of a novel robotic transcranial doppler system in subarachnoid hemorrhage, Sci. Rep., 12 (2022), 1–6. https://doi.org/10.1038/s41598-021-04751-1 doi: 10.1038/s41598-021-04751-1
    [113] T. Wang, Y. Chen, H. Du, Y. Liu, L. Zhang, M. Meng, Monitoring of neuroendocrine changes in acute stage of severe craniocerebral injury by transcranial Doppler ultrasound image features based on artificial intelligence algorithm, Comput. Math. Methods Med., 2021 (2021), 3584034. https://doi.org/10.1155/2021/3584034 doi: 10.1155/2021/3584034
    [114] M. L. P. Portegies, P. J. Koudstaal, M. A. Ikram, Cerebrovascular disease, in Handbook of Clinical Neurology (eds M. J. Aminoff and F. Boller), (2016), 239–261. https://doi.org/10.1016/B978-0-12-802973-2.00014-8
    [115] R. Capildeo, S. Haberman, F. C. Rose, The definition and classification of stroke: A new approach, QJM Int. J. Med., 47 (1978), 177–196. https://doi.org/10.1093/oxfordjournals.qjmed.a067535 doi: 10.1093/oxfordjournals.qjmed.a067535
  • This article has been cited by:

    1. Franz Teske, Jano Schubert, Adrian Fehrle, Felix Funk, Jörg Franke, Techno-economic analysis of battery storage systems and hydrogen-based storage systems as an alternative to grid expansion in the medium voltage grid in Germany, 2023, 11, 2333-8334, 358, 10.3934/energy.2023019
    2. B. Rajasekhara Reddy, S. Pranavanand, Naregalkar Akshay, 2023, Intelligent Control System for Solar Power Complementing with Grid Power, 979-8-3503-1398-7, 1, 10.1109/ICSCNA58489.2023.10370204
    3. Bahgat Ayasi, Iago X. Vázquez, Mohammed Saleh, Angel M. Garcia-Vico, Cristóbal J. Carmona, Application of spiking neural networks and traditional artificial neural networks for solar radiation forecasting in photovoltaic systems in Arab countries, 2025, 0941-0643, 10.1007/s00521-025-11066-z
  • Reader Comments
  • © 2023 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(3987) PDF downloads(304) Cited by(7)

Figures and Tables

Figures(4)

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog