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AIMS Medical Science

2018, Volume 5, Issue 2: 145-161. doi: 10.3934/medsci.2018.2.145
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Review

Update on management of acute respiratory distress syndrome

  • Intensive Care Unit, Queen Elizabeth Hospital, Hong Kong
  • Received: 31 December 2017 Accepted: 14 March 2018 Published: 21 March 2018

  • Acute respiratory distress syndrome (ARDS) is a frequent and life-threatening condition in intensive care units (ICUs). Management of ARDS remains challenging despite years of research. Morbidity and mortality are not only caused by the syndrome itself but can also be the result of ventilator-induced lung injury. In this article, an update on ARDS management including ventilator strategies, rescue therapies, pharmacological treatments, ICU supportive care, and rehabilitation is proposed. While lung protective ventilation remains the standard option for patients with ARDS, neuromuscular blockade and prone positioning are gaining support after successful trials. Helmet non-invasive ventilation and high-flow nasal cannula might be useful for mild-to-moderate ARDS. Extracorporeal membrane oxygenation and carbon dioxide removal are not recommended in standard practice although they might be useful in severe ARDS.

    Citation: Ka-man Fong, Shek-yin Au, Ka-lee Lily Chan, Wing-yiu George Ng. Update on management of acute respiratory distress syndrome[J]. AIMS Medical Science, 2018, 5(2): 145-161. doi: 10.3934/medsci.2018.2.145

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  • Acute respiratory distress syndrome (ARDS) is a frequent and life-threatening condition in intensive care units (ICUs). Management of ARDS remains challenging despite years of research. Morbidity and mortality are not only caused by the syndrome itself but can also be the result of ventilator-induced lung injury. In this article, an update on ARDS management including ventilator strategies, rescue therapies, pharmacological treatments, ICU supportive care, and rehabilitation is proposed. While lung protective ventilation remains the standard option for patients with ARDS, neuromuscular blockade and prone positioning are gaining support after successful trials. Helmet non-invasive ventilation and high-flow nasal cannula might be useful for mild-to-moderate ARDS. Extracorporeal membrane oxygenation and carbon dioxide removal are not recommended in standard practice although they might be useful in severe ARDS.


    1.   The Journal

    Networks and Heterogeneous Media (NHM) was founded in 2006 and has been growing successfully almost for 20 years. Responding to the journal's needs, NHM began its transformation at the end of 2022, officially changing to an OA publishing model in 2023 for the first time. From the start of the new submission system in August 2022 until December 20, 2023, the journal received a total of 330 submissions, and 80 were online, with a rejection rate of 73%, which shows that, despite the increase in publication, NHM has always maintained high standards and strict requirements. This would not have been possible without the support of our editor-in-chief and editorial board team. In the meantime, thanks to the whole EB for the work done, our editorial board has been enlarged this year with the inclusion of some outstanding young scholars. Next, journal development, manuscript processing, and future perspectives will be presented to share NHM's work and development this year.

    Submission Online Reject/Withdraw
    Data source from August 01, 2022–December 20, 2023.
    330 80 217/25

    2.   Manuscript processing

    Here you will find the processing time for each stage of the paper, the turnaround time for publication, and the national & regional statistics of the authors.

    2.1.   Manuscript processing time

    The processing time of the manuscript comprises three measurement indicators: Average Publication Time (APT), Submission to First Decision Time (TFD), and Acceptance to Publication Time (ATOP). Each indicator includes annual average time and quarterly time.

    1. APT

    In the figure, the horizontal axis represents the quarter-year, the vertical axis represents the number of days, and the bar graph represents the average value of APT for each quarter. The red line indicates the annual average ATP for the year 2022, while the green line represents the same for 2023.

    Since August 2023, the review period for NHM has been prolonged from 14 days to 30 days. Consequently, it is evident that starting from the second quarter of 2023, the publication cycle of NHM has progressively extended from approximately 2.6 months to 4.8 months. Ideally, the Average Publication Time (APT) for a manuscript in an Open Access (OA) journal is around 60 days.

    2. TFD

    TFD is the time from receipt of the manuscript to the first decision, including the time for the editorial board to do a brief check and the reviewers to review the manuscript. The average TFD for 2023 is 58.75 days. It is worth noting that the editors also waited for reviewers for much longer than 14 days when the required review period was 14 days. Similarly, after the required review time of 30 days, editors waited much longer than 30 days for reviewers, and in some holiday months, such as Christmas, it even went to 45–60 days.

    3. ATOP

    This section shows the average time from manuscript acceptance to publication, usually 10 days, which is influenced by the typesetting editor, the English editor, and the author's cooperation. The average ATOP for 2023 is 19.34 days.

    2.2.   Distribution of countries

    This section presents the geographic distribution of submitted manuscripts and published manuscripts. The distribution of author groups, serving as an indicator of a journal's future focus, constitutes a broad and influential category. This strong group has the potential to enhance the journal's citation impact, fostering its growth and prosperity.

    This view provides the counts of Submitted manuscripts per region and country. The region and country are derived by the affiliation of the author. The top 10 countries list is computed using Submitted articles descending for 2023.

    Submissions to NHM are mostly from countries in Asia, such as China, Saudi Arabia, Pakistan, etc.; final publications are mostly from countries in Asia and Europe, such as China, India, France, Italy, etc.

    3.   Journal development

    3.1.   Editorial board countries and regions

    Currently, NHM has 56 editorial board members from 14 countries on five continents, with the highest number of editorial board members from Europe, followed by Asia and North America.

    This year we have joined six new members of the Editorial Board, whose information is shown in the table below. We welcome them and hope to attract more outstanding scholars to join our team.

    Name Position Affiliation
    Xian-Ming Gu Associate Professor School of Mathematics, Southwestern University of Finance and Economics (SWUFE), Chengdu, China
    Dante Kalise Senior Lecturer Department of Mathematics, AMMP Section Imperial College London, UK
    Emiliano Cristiani Professor Istituto per le Applicazioni del Calcolo, Consiglio Nazionale delle Ricerche, Rome, Italy
    Eduardo Casas Renteria Professor Department of Applied Mathematics and Computer Science, E.T.S.I. Industriales and Telecommunication, University of Cantabria, Santander, Spain
    Giuseppe Maria Coclite Professor Department of Mechanics, Mathematics and Management Polytechnic University of Bari, Italy
    Delio Mugnolo Professor Faculty of Mathematics and Computer Science University of Hagen, Hagen, Germany

    3.2.   Article metrics

    Statistics of the most cited manuscripts of Web of Science in the last five years and the last two years, where the "*" after the title indicates that the manuscript is from a special issue manuscript.

    1. Most Cited Articles, 2023 (Last Five Years)

    Title Authors Publication Year Total Citations Average per Year
    Note: "*" Stands for Contributions to the Special Issue.
    Last Updated: December 2023
    Source: Web of Science
    Multiscale models of COVID-19 with mutations and variants* Nicola Bellomo,
    Diletta Burini,
    Nisrine Outada    		 2022 29 14.5
    Emergent behavior of cucker-smale model with normalized weights and distributed time delays Young-Pil Choi,
    Cristina Pignotti    		 2019 21 4.2
    Non-local multi-class traffic flow models Felisia Angela Chiarello, Paola Goatin 2019 17 3.4
    Opinion formation in voting processes under bounded confidence Sergei Yu Pilyugin,
    M. C. Campi    		 2019 16 3.2
    Energy and implicit discretization of the Fokker-Planck and Keller-Segel type equations* Luis Almeida,
    Federica Bubba,
    Benoit Perthame,
    Camille Pouchol    		 2019 16 3.2
    Deep neural network approach to forward-inverse problems Hyeontae Jo,
    Hwijae Son,
    Hyung Ju Hwang,
    Eun Heui Kim    		 2020 13 3.25
    Relative entropy method for the relaxation limit of hydrodynamic models* Jose Antonio Carrillo, Yingping Peng,
    Aneta Wroblewska-Kaminska    		 2020 11 2.75
    Homogenization of Bingham flow in thin porous media Maria Anguiano,
    Renata Bunoiu    		 2020 11 2.75
    Incompressible limit of a continuum model of tissue growth for two cell populations Pierre Degond,
    Sophie Hecht,
    Nicolas Vauchelet    		 2020 11 2.75
    Existence results and stability analysis for a nonlinear fractional boundary value problem on a circular ring with an attached edge: a study of fractional calculus on metric graph Vaibhav Mehandiratta,
    Mani Mehra,
    Guenter Leugering    		 2021 10 3.33

    2. Most Cited Articles, 2023 (Last Two Years)

    Title Authors Publication Year Total Citations Average per Year
    Note: "*" Stands for Contributions to the Special Issue.
    Last Updated: December 2023
    Source: Web of Science
    Multiscale models of COVID-19 with mutations and variants* Nicola Bellomo,
    Diletta Burini,
    Nisrine Outada    		 2022 29 14.5
    Compactness property of the linearized Boltzmann operator for a diatomic single gas model Stephane Brull,
    Marwa Shahine,
    Philippe Thieullen    		 2022 5 2.5
    An sir-like kinetic model tracking individuals' viral load* Rossella Della Marca,
    Nadia Loy,
    Andrea Tosin    		 2022 5 2.5
    A study of computational and conceptual complexities of compartment and agent based models* Prateek Kunwar,
    Oleksandr Markovichenko,
    Monique Chyba,
    Yuriy Mileyko,
    Alice Koniges,
    Thomas Lee    		 2022 5 2.5
    Homogenization of nonlinear nonlocal diffusion equation with periodic and stationary structure Junlong Chen,
    Yanbin Tang    		 2023 3 3
    Global solution to the Cauchy problem of fractional drift diffusion system with power-law nonlinearity Caihong Gu,
    Yanbin Tang    		 2023 3 3
    Vaccination strategies through intra-compartmental dynamics* Rinaldo M. Colombo, Francesca Marcellini,
    Elena Rossi    		 2022 3 1.5
    A measure model for the spread of viral infections with mutations* Xiaoqian Gong,
    Benedetto Piccoli    		 2022 3 1.5
    Optimization of vaccination for COVID-19 in the midst of a pandemic* Qi Luo,
    Ryan Weightman,
    Sean T. McQuade,
    Mateo Diaz,
    Emmanuel Trelat,
    William Barbour,
    Dan Work,
    Samitha Samaranayake, Benedetto Piccoli    		 2022 3 1.5
    Asymptotic flocking of the relativistic Cucker-Smale model with time delay Hyunjin Ahn 2023 2 2

    3.3.   Special issues

    Only the number of submissions and rejections, publications for the special issue were counted from August 1, 2022, to December 20, 2023.

    Special Issue Submissions Rejection and withdrawal Published
    136 53/12 60

    The data counts the submissions, rejections, and published manuscripts for special issues established in 2023.

    Title Established Contribute Accept Reject
    Recent advances in numerical methods for integer-and fractional-order PDEs 2022-08-23 47 29 18
    Nonlocal conservation laws 2022-08-24 7 5 1
    New trends on discrete networks 2022-09-27 31 12 15
    Traffic and autonomy 2023-01-11 7 7 0
    Advanced Mathematical Methodologies to Manage Pandemics 2023-05-04 9 2 3
    Interdisciplinary Approaches for Understanding Networks and Heterogeneous Media 2023-05-09 17 5 11
    Numerical Simulation and Mathematical Modelling 2023-11-03 14 0 6
    Nonlinear PDEs in material science 2023-11-16 0 0 0
    Analysis of Analytical, Computational and ML-based Approaches for Differential and Integral Equations 2023-11-29 0 0 0

    4.   Summary and perspective

    4.1.   Summary

    The successful publication of 80 excellent papers in 2023, the first year of the official conversion to an OA journal, would not have been possible without the support of the editorial board members, the editor-in-chief, and the contributions of authors and reviewers. Although the impact factor has dropped a bit from the previous year, it is believed that it will gradually increase.

    4.2.   Perspective

    At present, there are some problems that we need to improve in the next step: the manuscript processing cycle is longer than other OA journals; the editorial board needs to be further expanded, and the promotion of the journal needs to be further improved.

    Next year, everything will be better.

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