Prevalence and factors associated with chronic Hepatitis B infection among adults in the Central Highland, Vietnam

Pham Ngoc Thanh; Nguyen Thi Thi Tho; Tran Dac Phu; Tran Dai Quang; Nguyen Thuy Duong; Vien Chinh Chien; Phan Trong Lan; Pham Ngoc Thanh; Nguyen Thi Thi Tho; Tran Dac Phu; Tran Dai Quang; Nguyen Thuy Duong; Vien Chinh Chien; Phan Trong Lan

doi:10.3934/medsci.2020023

AIMS Medical Science

2020, Volume 7, Issue 4: 337-346. doi: 10.3934/medsci.2020023

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Research article

Prevalence and factors associated with chronic Hepatitis B infection among adults in the Central Highland, Vietnam

1.
Head of Epidemiology Department, Tay Nguyen Institute of Hygiene and Epidemiology, 34 Pham Hung, Buon Ma Thuot, Dak Lak, Vietnam
2.
National Institute of Hygiene and Epidemiology, 01 Yec Xanh, Hai Ba Trung, Hanoi, Vietnam
3.
General Department of Preventive Medicine, Ministry of Health, 135 Nui Truc, Ba Dinh, Hanoi, Vietnam
4.
Pasteur Institute in Ho Chi Minh City, 167 Pasteur, District 3, Ho Chi Minh City, Vietnam

Received: 14 September 2020 Accepted: 07 December 2020 Published: 14 December 2020

Objective The study was conducted to estimate the prevalence of chronic hepatitis B infection and related factors among adult population in Central Highland, 2018.
Methods The study applied the cross-sectional descriptive design with the combination of structured interview and serological blood tests. There were 2428 respondents in 03 provinces, namely Kon Tum, Gia Lai, Dak Nong included in the study which was conducted from September to December 2018.
Results The prevalence of hepatitis B infection among adults in Central Highland was 11.2% with the positive uniformity among provinces in the region. The findings also showed that male adults, farmers and those who have relatives with liver disease and experienced the kidney dialysis possessed a higher rate of hepatitis B virus infection than the one of other groups. The findings also showed that the respondents had a low uptake of the vaccine among infected group (6.3%). Study subjects with vaccination were less affected by hepatitis B virus infection rate than the ones without vaccination.
Conclusions The high prevalence of chronic hepatitis B in the Central Highland indicates that it needs much more attention of Ministry of Health and local authorities for prevention of infection through mother-to-child transmission and early infection due to late immunization and more rescue investment for diagnostic, evaluation, follow up and treatment of people with chronic HBV infection. The consideration regarding occupations, family history of liver diseases is also required for during the intervention implementation.
- chronic Hepatitis B,
- prevalence,
- associated factors, Central Highland,
- Vietnam
Citation: Pham Ngoc Thanh, Nguyen Thi Thi Tho, Tran Dac Phu, Tran Dai Quang, Nguyen Thuy Duong, Vien Chinh Chien, Phan Trong Lan. Prevalence and factors associated with chronic Hepatitis B infection among adults in the Central Highland, Vietnam[J]. AIMS Medical Science, 2020, 7(4): 337-346. doi: 10.3934/medsci.2020023

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Abstract

Objective The study was conducted to estimate the prevalence of chronic hepatitis B infection and related factors among adult population in Central Highland, 2018.

Methods The study applied the cross-sectional descriptive design with the combination of structured interview and serological blood tests. There were 2428 respondents in 03 provinces, namely Kon Tum, Gia Lai, Dak Nong included in the study which was conducted from September to December 2018.

Results The prevalence of hepatitis B infection among adults in Central Highland was 11.2% with the positive uniformity among provinces in the region. The findings also showed that male adults, farmers and those who have relatives with liver disease and experienced the kidney dialysis possessed a higher rate of hepatitis B virus infection than the one of other groups. The findings also showed that the respondents had a low uptake of the vaccine among infected group (6.3%). Study subjects with vaccination were less affected by hepatitis B virus infection rate than the ones without vaccination.

Conclusions The high prevalence of chronic hepatitis B in the Central Highland indicates that it needs much more attention of Ministry of Health and local authorities for prevention of infection through mother-to-child transmission and early infection due to late immunization and more rescue investment for diagnostic, evaluation, follow up and treatment of people with chronic HBV infection. The consideration regarding occupations, family history of liver diseases is also required for during the intervention implementation.

Conflicts of interest

All authors declare that there is no conflict of interest.

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