
Citation: Moncef ATI, Rachid BOUAMRANE, Djamel ADDI, Fatima Zohra MAROC, Fatima Zohra Mecheret. Monte Carlo dose index estimation in computed tomography[J]. AIMS Bioengineering, 2020, 7(4): 224-235. doi: 10.3934/bioeng.2020019
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The ionization radiation devices are presently very common at the present time in different medical areas, being the most important tool in the diagnostics process. One of the applications of ionization radiation as X-ray computed tomography demand knowledge of the radiation energy deposited in the matter to estimate biological effects [1],[2]. Where the computed tomography (CT) examination gives around 10–50 more doses than the absorbed doses to a patient under conventional X-ray radiology [3], in the other hand, the number of CT examinations has been rapidly increasing in recent year, this is explained by the reason that the CT exam is more interpretable than the conventional radiology by the radiologists [4]. There is the problem of patient exposition over several problems of medical physics and radiation protection to be solved. In 2005 BEIR VII [5] and 103 ICRP [6] reports mentioned that the risk assessment depends on tow parameters: first, the patient organ dose. Second, it is patient sex. Here the organ's absorbed dose for different energy photons was larger than the lower energy photon (kVp) at the same current tube (mAs), because of their penetration power. However, the minimization of radiation absorbed doses is very suitable, where recently the development of modern technology research in CT scan devices based on the dynamic filter [7] plays a crucial role in the performance optimization techniques, by placing a dynamic Bowtie filter between the X-ray source and the patient to be imaged in the FOV region. In this case, the beam filtered by the dynamic Bowtie filter optimizes the beam intensity. The proposed technique of the dynamic Bowtie filter reduced the scattering beam by blocking the low energy of the X-ray source. One of the most important methods of estimating the absorbed dose on the medical imaging system has been involved in the Monte Carlo simulation code to calculate the absorbed dose into different organs [8],[9],[10],[11]. This approach is based on random variable sampling, where it comes very usually into use in several advanced numerical simulation techniques such as generalized methods. However, radiation doses in conventional radiology examinations such as computed tomography (CT) examinations are often performed using GATE. The GATE (Geant Application for Tomography Emission) was created to simulate all kinds of interactions between matter and particles in the area of medical imaging and radiotherapy. Where the GATE is an important tool to obtain an estimated absorbed dose in radiology devices based on the stochastic process [12],[13]. There are some studies based on GATE software using different X-ray spectrum production based on the SRS-78 program [14] was completed, also using Mote Carlo techniques [15]. Dosimetry in CT scan is an important aspect of conventional radiology to estimate the risk versus benefit factor [16].
The CT dose index estimation was performed on a circular phantom made by PMMA (Polymethylmetacryhate). The phantom contains different cylindrical holes of diameter equal to 10 mm to put the detector inside the field of view (FOV) region. The geometry of the PMMA phantom was configured as illustrated in Figure 1. Hence, the Computed Tomography Dose Index (CTDI) estimating must be made regularly to ensure the CT performance. Gate/Geant4 model was used to build a computational model for estimation the deposited doses in the CT scan system, where different CT parameters (Slice, kVp, mAs) have been used to evaluate the dose index value with a 1 cm beam collimator by irradiating the cylindrical phantom with a fan-beam from an X-ray tube in a rotation motion [17],[18]. Figure 1 shows the simulation set up used in the present work. Here we have the phantom and the scanner couch rotated around the z-axis, and the scanner couch was rotated around the z-axis, and the X-ray tube was in a stationary position as shown in Figure 1.
The study was performed by Monte-Carlo simulation to evaluate the absorbed dose in CT procedures using Gate software. In witch, all computer tomography doses index (CTDI) measurements were performed on PMMA phantom (head and abdominal) with the length of 15 cm and the diameter between 16 and 32 cm, respectively, the PMMA phantom was positioned at a distance equal to 54 cm from the X-ray source to the PMMA iso-center, according to the manufacturer's protocols. The measurements were analyzed under several-tube current range between 100–450 (mAs) in five regions of the PMMA phantom in the central hole position (CTDIc), and at four peripheral holes (CTDIp) (see
D(z) represents the dose profile along the rotation axis z.
B.W is the X-ray beam width.
z is the width profil.
L ionization chamber length.
The dose length CTDIw is given by the following the
When the CTDI quantity was calculated in terms of the integral over the length of phantom, from
Simulates X-ray spectra using SPEKTR3.0 software [19], several variables that impact the X-ray beam spectrum are defined as anode angle, filter thickness, and material. SPEKTR3.0 is a computational toolkit that calculates X-ray spectra using TASMICS algorithm spectral model [22]. The SPEKTR3.0 toolkit includes a Matlab release 2013b (The Mathworks, Natick MA) to calculate X-ray beam spectra. Figure 2 shows the X-ray beam profile calculated using various photon energy (kVp) and tube current (mAs) variables.
The dependences of CTDI100,c, CTDI100,p and CTDI100,w on the photon energy (kVp) under various tube current (mAs) are shown in Figures 3–5, respectively. The X-ray beam thickness was equal to 1 cm. For the same parameters, the dependencies of absorbed dose (CTDI) on the PMMA phantom diameter under several (kVp) and (mAs) of photon beams are shown in Figures 6 and 7. Figures 8 and 9 show that the CTDI at the iso-center of the central hole is a function of tube current (mAs) for several PMMA phantom diameter and photon energy (kVp), respectively. A fit represented by a dashed line is shown in Figure 10 calculation processes in this study, that CTDI100,w was calculated using 140 kV and 1 sec acquisition time for one rotation X-ray tube.
kVp | Abdominal phantom | Head phantom |
80 | 2.3 | 17.0 |
100 | 3.1 | 19.0 |
120 | 4.0 | 21.6 |
140 | 4.3 | 23.3 |
According to Figures 3–5, the dose measurements of CTDI100,c, CTDI100,p and CTDI100,w at the different points of the PMMA phantom (center and peripheral hole) under various current tube (mAs) was increased under a non-linearly way for several tube current values (mAs), already confirmed by the previous paper [15].
In these studies, the PMMA dose level was estimated for several diameters. Whereas, the results of these calculations are shown in
where d represents the diameter of the CTDI phantom used.
In Figures 8 and 9, however, with increasing tube current (mAs), the measured CTDI values at the central position of the ionization chamber increase under a linear function way for each PMMA diameter and different X-ray beam energy (kVp) values, respectively. Contrary to the evolution of CTDI as a function of the photon energy (kVp) parameter where the dose increases, a non-linear shape was noted in Figure 3 at the same Monte Carlo simulation conditions.
In
Table 1 represents the results as the weighted computer tomography dose index (CTDIw) measured on (mGy) for the abdominal and head phantom volume. Where, columns 1 represents the energy of the X-ray beam used under 100 (mAs) tube current and 1 sec acquisition time. Columns 2 and 3 show the results for the PMMA abdominal and head volumes, respectively. An excellent agreement can be seen between our results, and that discussed by R. Kramer et al. in the paper [23].
In this paper, we have discussed the computed tomography dose index (CTDI) estimation for various diameter organs using PMMA phantom characteristics that were implemented based on the Monte Carlo method. We have therefore modeled all physical aspects of a simple CT scan device. A different energy spectral value of X-ray tube dose was calculated under the SPEKTR3.0 software. It was also integrated into the simulation protocol of dose measurements. After 107 particles were generated, measurements of CTDI organs were taken in the head and abdominal phantoms at different parameters such as photon energy (kVp) and tube current (mAs) levels. The results of this study confirmed that the CT dose decreased non-linearly shape as a function of the diameters for various (kVp) and (mAs) values. Also, the CT dose increased non-linearly as a function of the (kVp) values for different (mAs) values but is linearly function increase as function tube current (mAs) values. In the second part, we demonstrated that for the smaller diameters, the absorbed dose (CTDI) increased when the tube current (mAs) is increased and in the different position of the ionization chamber. This result indicates that the average percent absorbed dose received by an abdominal phantom with a diameter equal to 64 cm was lower than 80% of the CTDI value received by the head phantom of 16 cm of diameter, which was slightly higher. Further research simulation for a very high number of particles using GPU code has to be accomplished to decrease the computation time and to obtain a good realistic simulation. Dynamic Bowtie beam CT will also be investigated in that simulation context in the future.
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kVp | Abdominal phantom | Head phantom |
80 | 2.3 | 17.0 |
100 | 3.1 | 19.0 |
120 | 4.0 | 21.6 |
140 | 4.3 | 23.3 |