The composition of microbial communities in inflammatory periodontal diseases in young adults Tatars

Maya Kharitonova; Peter Vankov; Airat Abdrakhmanov; Elena Mamaeva; Galina Yakovleva; Olga Ilinskaya; Maya Kharitonova; Peter Vankov; Airat Abdrakhmanov; Elena Mamaeva; Galina Yakovleva; Olga Ilinskaya

doi:10.3934/microbiol.2021005

AIMS Microbiology

2021, Volume 7, Issue 1: 59-74. doi: 10.3934/microbiol.2021005

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Research article

The composition of microbial communities in inflammatory periodontal diseases in young adults Tatars

1.
Institute of Fundamental Medicine and Biology, Kazan Federal University, Kremlevskaya Str. 18, Kazan 420008, Russia
2.
Department of Pediatric Dentistry, Kazan State Medical University, Butlerova Str. 49, Kazan 420012, Russia

Received: 15 October 2020 Accepted: 19 January 2021 Published: 27 January 2021

Host susceptibility and environmental factors are important for the development of gingivitis and periodontitis, but bacterial biofilms attached to the teeth and gingival tissues play a crucial role. We have analyzed and compared the subgingival microbial communities between subjects with dental plaque biofilm-induced generalized chronic gingivitis (CG), localized initial (Stage I) periodontitis (IP) and healthy controls (HC) of young people aged 18–19 years permanently residing in the city of Kazan (Tatarstan, Russia). The results showed that the α-diversity in groups with CG and IP was higher than in the healthy group. In a course of periodontal disease, a decrease in the relative abundance of dominates genera Rothia and Streptococcus was observed along with increase of class TM7-3 (Candidatus Saccharibacteria phylum) representatives. Also, the increase of red complex representatives Porphyromonadeceae, Treponema and Tannerella was detected together with statistically significant increase of Filifactor, Parvimonas, Peptostreptococcaceae, Veillonellaceae, Tissierelaceae and Mogibacteriaceae. Analysis of our data suggests that transition from HC to IP may be accompanied by a decrease in microbial diversity and a reduction in the abundance of family Rs-045 (Candidatus Saccharibacteria phylum), Desulfovibrionaceae Corynebacterium, Campylobacter and Selenomonas in young adults Kazan Tatars.
- periodontitis,
- gingivitis,
- dental biofilm,
- young adult,
- oral microbial,
- α-diversity,
- TM7-3,
- Candidatus Saccharibacteria,
- Rothia,
- Streptococcus
Citation: Maya Kharitonova, Peter Vankov, Airat Abdrakhmanov, Elena Mamaeva, Galina Yakovleva, Olga Ilinskaya. The composition of microbial communities in inflammatory periodontal diseases in young adults Tatars[J]. AIMS Microbiology, 2021, 7(1): 59-74. doi: 10.3934/microbiol.2021005

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Abstract

Host susceptibility and environmental factors are important for the development of gingivitis and periodontitis, but bacterial biofilms attached to the teeth and gingival tissues play a crucial role. We have analyzed and compared the subgingival microbial communities between subjects with dental plaque biofilm-induced generalized chronic gingivitis (CG), localized initial (Stage I) periodontitis (IP) and healthy controls (HC) of young people aged 18–19 years permanently residing in the city of Kazan (Tatarstan, Russia). The results showed that the α-diversity in groups with CG and IP was higher than in the healthy group. In a course of periodontal disease, a decrease in the relative abundance of dominates genera Rothia and Streptococcus was observed along with increase of class TM7-3 (Candidatus Saccharibacteria phylum) representatives. Also, the increase of red complex representatives Porphyromonadeceae, Treponema and Tannerella was detected together with statistically significant increase of Filifactor, Parvimonas, Peptostreptococcaceae, Veillonellaceae, Tissierelaceae and Mogibacteriaceae. Analysis of our data suggests that transition from HC to IP may be accompanied by a decrease in microbial diversity and a reduction in the abundance of family Rs-045 (Candidatus Saccharibacteria phylum), Desulfovibrionaceae Corynebacterium, Campylobacter and Selenomonas in young adults Kazan Tatars.

Acknowledgments

The study was performed within the Russian Government Program of Competitive Growth of Kazan Federal University. Equipment of the Interdisciplinary Center for Collective Use [ID RFMEFI59414X0003] sponsored by Ministry of Education and Science of the Russian Federation was used.

Conflict of interest

The authors declare no conflict of interest.

Author contributions

Conceptualization, O.I. and E.M.; acquisition and analysis of data, A.A., G.Y., M.K.; visualization and interpretation of data, P.V. and M.K.; writing-original draft preparation, O.I. and M.K.; writing-review and editing, P.V., A.A., M.K., E.M., G.Y. and O.I. All authors have read and agreed to the published version of the manuscript.

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