Effects of EEG examination and ABA-therapy on resting-state EEG in children with low-functioning autism

Galina V. Portnova; Oxana Ivanova; Elena V. Proskurnina; Galina V. Portnova; Oxana Ivanova; Elena V. Proskurnina

doi:10.3934/Neuroscience.2020011

AIMS Neuroscience

2020, Volume 7, Issue 2: 153-167. doi: 10.3934/Neuroscience.2020011

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Review Topical Sections

Effects of EEG examination and ABA-therapy on resting-state EEG in children with low-functioning autism

1.
Institute of Higher Nervous Activity and Neurophysiology of RAS, 5A Butlerova St., Moscow 117485, Russia
2.
FSBI Federal medical center Rosimushchestvo, 31 Kalanchevskaya str., 107078, Moscow, Russia
3.
Research Centre for Medical Genetics, 1 Moskvorechye St., Moscow 115522, Russia

Received: 05 March 2020 Accepted: 01 June 2020 Published: 05 June 2020

Objective We aimed to study the effects of EEG examination and ABA-therapy on resting-state EEG in children with low-functioning autism and tactile defensiveness.
Methods We have performed this study with three cohorts of preschoolers: children with autistic spectrum disorder (ASD) who needed applied behavior analysis (ABA) therapy due to their tactile defensiveness; children with ASD who didn't need ABA therapy; and the control group of healthy children. Number of microstates was determined in the initial and final parts of the resting-state EEGs.
Results and conclusions Children with higher tactile defensiveness for the most part had specific EEG microstates associated with unpleasant emotions and senses. The EEG microstates of children with ASD who did not need ABA therapy, had more similarities with the EEG microstates of typically developing children except for temporary changes. Meanwhile, the children with tactile defensiveness demonstrated typical patterns of EEG microstates from start to finish of the procedure.
- EEG,
- low functioning autism,
- tactile defensiveness,
- applied behavior analysis,
- resting state,
- microstate
Citation: Galina V. Portnova, Oxana Ivanova, Elena V. Proskurnina. Effects of EEG examination and ABA-therapy on resting-state EEG in children with low-functioning autism[J]. AIMS Neuroscience, 2020, 7(2): 153-167. doi: 10.3934/Neuroscience.2020011

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Abstract

Objective We aimed to study the effects of EEG examination and ABA-therapy on resting-state EEG in children with low-functioning autism and tactile defensiveness.

Methods We have performed this study with three cohorts of preschoolers: children with autistic spectrum disorder (ASD) who needed applied behavior analysis (ABA) therapy due to their tactile defensiveness; children with ASD who didn't need ABA therapy; and the control group of healthy children. Number of microstates was determined in the initial and final parts of the resting-state EEGs.

Results and conclusions Children with higher tactile defensiveness for the most part had specific EEG microstates associated with unpleasant emotions and senses. The EEG microstates of children with ASD who did not need ABA therapy, had more similarities with the EEG microstates of typically developing children except for temporary changes. Meanwhile, the children with tactile defensiveness demonstrated typical patterns of EEG microstates from start to finish of the procedure.

Limitations

Unfortunately, we had the only one attempt to divide children with low-functioning ASD in two groups. If child refused to participate in EEG study, he received ABA therapy or was excluded from the study. The tactile hypersensitivity was not the only reason which didn't allow conducting a study on the first attempt, the four children with ASD excluded from the study because of the unmotivated aggression, disruptive behavior and even fever. Because of the difficulties to recruit participants in advance, we had to divide groups after the attempt to perform an EEG examination.

Funding

The reported study was funded by RFBR according to the research project № 18-00-01670 (18-00-01511) and the state assignment of Ministry of Education and Science of the Russian Federation for 2019-2021 (No. АААА-А17-117092040004-0).

Conflict of interests

The authors have no conflicts of interest to disclose.

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