Editorial Special Issues

Differential equations frameworks and models for the physics of biological systems

  • Received: 15 June 2024 Revised: 21 June 2024 Accepted: 21 June 2024 Published: 26 June 2024
  • The modeling of biological systems has recently gained much attention considering the possibility to describe the time evolution of a biological system by employing differential equations. Different frameworks have been proposed depending on the number of dynamic variables. Ordinary differential equations (ODE) are employed if time is the only dynamic variable; partial differential equations (PDE) are proposed when, in addition to the time variable, space and/or velocity variables are considered. In the context of differential equation models, new frameworks have been proposed where stochastic terms are added to classical deterministic terms. A specific model is proposed when the differential equations are coupled to initial and/or boundary conditions. This editorial article deals with the topic of this special issue, which is devoted to the new developments in the multiscale modeling of complex biological systems with special attention to the interplay between different scholars.

    Citation: Carlo Bianca. Differential equations frameworks and models for the physics of biological systems[J]. AIMS Biophysics, 2024, 11(2): 234-238. doi: 10.3934/biophy.2024013

    Related Papers:

  • The modeling of biological systems has recently gained much attention considering the possibility to describe the time evolution of a biological system by employing differential equations. Different frameworks have been proposed depending on the number of dynamic variables. Ordinary differential equations (ODE) are employed if time is the only dynamic variable; partial differential equations (PDE) are proposed when, in addition to the time variable, space and/or velocity variables are considered. In the context of differential equation models, new frameworks have been proposed where stochastic terms are added to classical deterministic terms. A specific model is proposed when the differential equations are coupled to initial and/or boundary conditions. This editorial article deals with the topic of this special issue, which is devoted to the new developments in the multiscale modeling of complex biological systems with special attention to the interplay between different scholars.


    加载中


    [1] Hirsch C, Schildknecht S (2019) In vitro research reproducibility: Keeping up high standards. Front Pharmacol 10: 1484. https://doi.org/10.3389/fphar.2019.01484
    [2] Lipatov VA, Kryukov AA, Severinov DA, et al. (2019) Ethical and legal aspects of in vivo experimental biomedical research. I.P. Pavlov Russian Medical Biological Herald 27: 80-92. https://doi.org/10.23888/PAVLOVJ201927180-92
    [3] (1999) National Research CouncilSummary of advantages and disadvantages of in vitro and in vivo methods. Monoclonal Antibody Production. Washington: National Academies Press.
    [4] Nair A, Chauhan P, Saha B, et al. (2019) Conceptual evolution of cell signaling. Int J Mol Sci 20: 3292. https://doi.org/10.3390/ijms20133292
    [5] Bar-Yam Y (1999) Dynamics of Complex System (Studies in Nonlinearity).CRC Press.
    [6] Nicolis G, Nicolis C (2009) Foundations of complex systems: Nonlinear dynamics. Statistical Physics, Information and Prediction.Cambridge University Press. https://doi.org/10.1017/S1062798709000738
    [7] Bianca C, Bellomo N (2011) Towards a mathematical theory of complex biological systems. Series in Mathematical Biology and Medicine.World Scientific Publishing Co. Pte. Ltd.
    [8] Gunawardena J (2014) Models in biology: accurate descriptions of our pathetic thinking. BMC Biol 12: 29. https://doi.org/10.1186/1741-7007-12-29
    [9] Britton NF (2003) Essential mathematical biology. Springer Undergraduate Mathematics Series.Springer-Verlag London.
    [10] Glaser R (2012) Biophysics: an Introduction.Springer.
    [11] Hatze H (1974) The meaning of the term ‘biomechanics’. J Biomech 7: 189-190. https://doi.org/10.1016/0021-9290(74)90060-8
    [12] Hogeweg P (2011) The roots of bioinformatics in theoretical biology. PLoS Comput Biol 7: e1002021. https://doi.org/10.1371/journal.pcbi.1002021
    [13] Barrera A, Román-Román P, Torres-Ruiz F (2020) Two stochastic differential equations for modeling oscillabolastic-type behavior. Mathematics 8: 155. https://doi.org/10.3390/math8020155
    [14] Perea A, Predtetchinski A (2019) An epistemic approach to stochastic games. Int J Game Theory 48: 181-203. https://doi.org/10.1007/s00182-018-0644-8
    [15] Bonyah E, Juga ML, Matsebula LM, et al. (2023) On the modelling of COVID-19 spread via fractional derivative: a stochastic approach. Math Models Comput Simul 15: 338-356. https://doi.org/10.1134/S2070048223020023
    [16] Chauvière A, Preziosi L, Verdier C (2010). Cell Mechanics: from Single Scale-Based Models to Multiscale Modeling, London: CRC Press
    [17] Amar MB, Bianca C (2016) Towards a unified approach in the modeling of fibrosis: a review with research perspectives. Phys Life Rev 17: 61-85. https://doi.org/10.1016/j.plrev.2016.03.005
    [18] Castiglione F, Pappalardo F, Bianca C, et al. (2014) Modeling biology spanning different scales: an open challenge. BioMed Res Inter 2014: 902545. https://doi.org/10.1155/2014/902545
    [19] Bai Q, Ren F, Fujita K, et al. (2017) Multi-agent and Complex Systems. Singapore: Springer.
    [20] Van Liedekerke P, Palm MM, Jagiella N, et al. (2015) Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results. Comput Part Mech 2: 401-444. https://doi.org/10.1007/s40571-015-0082-3
    [21] Hasdemir D, Hoefsloot HCJ, Smilde AK (2015) Validation and selection of ODE based systems biology models: how to arrive at more reliable decisions. BMC Syst Biol 9: 32. https://doi.org/10.1186/s12918-015-0180-0
  • Reader Comments
  • © 2024 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(683) PDF downloads(47) Cited by(0)

Article outline

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog