Advanced platelet rich fibrin in periodontal regeneration

Aishwarya Rathod; Priyanka Jaiswal; Deepika Masurkar; Aishwarya Rathod; Priyanka Jaiswal; Deepika Masurkar

doi:10.3934/bioeng.2023012

AIMS Bioengineering

2023, Volume 10, Issue 2: 175-182. doi: 10.3934/bioeng.2023012

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Advanced platelet rich fibrin in periodontal regeneration

Department of Periodontics, Sharad Pawar Dental College and Hospital, Datta Meghe institute of Higher Education and Research (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra 442001, India

Received: 03 April 2023 Revised: 16 May 2023 Accepted: 23 May 2023 Published: 13 June 2023

Regenerating periodontal tissue is the main goal of periodontal therapy. Periodontal tissue regeneration involves the development of new bone, cement, and periodontal ligaments on damaged tooth root surfaces in order to restore anatomy and function. In order to further enhance PRF (Platelet rich fibrin) and develop advanced platelet-rich fibrin, a slower rotating speed is proposed (A-PRFs). Cell dispersion is affected by centrifugation rate. The majority of the leukocytes in the PRF are concentrated near the bottom of the tube due to centrifugation rate. By switching the centrifugation process to 1,500 rpm for 14 minutes, granulocyte neutrophils and the fibrin matrix are more evenly distributed in the A-PRF created. Hence, a periodontal evaluation of this subject is required.
- centrifugation,
- growth factors,
- platelets,
- regeneration
Citation: Aishwarya Rathod, Priyanka Jaiswal, Deepika Masurkar. Advanced platelet rich fibrin in periodontal regeneration[J]. AIMS Bioengineering, 2023, 10(2): 175-182. doi: 10.3934/bioeng.2023012

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Abstract

Regenerating periodontal tissue is the main goal of periodontal therapy. Periodontal tissue regeneration involves the development of new bone, cement, and periodontal ligaments on damaged tooth root surfaces in order to restore anatomy and function. In order to further enhance PRF (Platelet rich fibrin) and develop advanced platelet-rich fibrin, a slower rotating speed is proposed (A-PRFs). Cell dispersion is affected by centrifugation rate. The majority of the leukocytes in the PRF are concentrated near the bottom of the tube due to centrifugation rate. By switching the centrifugation process to 1,500 rpm for 14 minutes, granulocyte neutrophils and the fibrin matrix are more evenly distributed in the A-PRF created. Hence, a periodontal evaluation of this subject is required.

Acknowledgments

Authors acknowledge the immense help received from the scholars whose articles are cited and included in references to this manuscript. The authors are also grateful to authors/editors/publishers of all those articles, journals and booksfrom where the literature for this article has been reviewed and discussed.

Use of AI tools declaration

The authors declare they have not used Artificial Intelligence (AI) tools in the creation of this article.

Conflict of interest

The authors declare no conflict of interest.

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