Review

Narrative Review of Vitamin D and Its Specific Impact on Balance Capacity in Older Adults

  • Received: 16 November 2016 Accepted: 24 November 2016 Published: 30 November 2016
  • Introduction and Aims: Falls injuries among older adults, a widespread well-established contributor to high disability levels, excess morbidity and mortality rates, have many causes. This review examines the association between vitamin D levels and postural stability or balance control—a fairly consistent predictor of falls among older adults. Materials and Method: All relevant English language peer reviewed research publications detailing the relationship between vitamin D levels and balance control among the elderly were sought. Key words included “Vitamin D and Balance or Postural Control.” Databases used were Academic Search Complete, PubMed, Scopus, and Web of Science. Results: Analysis showed no consistent association to exist between the key variables of interest examined-indeed, despite years of study, there as many positive studies as negative studies, regardless of study design. Conclusion: More research is needed to support the use of vitamin D supplementation for purposes of improving balance capacity among older adults. Geriatric clinicians can however, expect this form of intervention to be more protective then not against falls injuries among those with both concomitant vitamin D deficiencies and poor balance control.

    Citation: Ray Marks. Narrative Review of Vitamin D and Its Specific Impact on Balance Capacity in Older Adults[J]. AIMS Medical Science, 2016, 3(4): 345-358. doi: 10.3934/medsci.2016.4.345

    Related Papers:

  • Introduction and Aims: Falls injuries among older adults, a widespread well-established contributor to high disability levels, excess morbidity and mortality rates, have many causes. This review examines the association between vitamin D levels and postural stability or balance control—a fairly consistent predictor of falls among older adults. Materials and Method: All relevant English language peer reviewed research publications detailing the relationship between vitamin D levels and balance control among the elderly were sought. Key words included “Vitamin D and Balance or Postural Control.” Databases used were Academic Search Complete, PubMed, Scopus, and Web of Science. Results: Analysis showed no consistent association to exist between the key variables of interest examined-indeed, despite years of study, there as many positive studies as negative studies, regardless of study design. Conclusion: More research is needed to support the use of vitamin D supplementation for purposes of improving balance capacity among older adults. Geriatric clinicians can however, expect this form of intervention to be more protective then not against falls injuries among those with both concomitant vitamin D deficiencies and poor balance control.


    加载中
    [1] Bogaerts A, Delecluse C, Boonen S, et al. (2011) Changes in balance, functional performance and fall risk following whole body vibration training and vitamin D supplementation in institutionalized elderly women. A 6 month randomized controlled trial. Gait Posture 33: 466-472. doi: 10.1016/j.gaitpost.2010.12.027.
    [2] Luk JK, Chan TY, Chan DK (2015) Falls prevention in the elderly: translating evidence into practice. Hong Kong Med J 21: 165-171. doi: 10.12809/hkmj144469.
    [3] Fraix M (2012) Role of the musculoskeletal system and the prevention of falls. J Am Osteopath Assoc 112: 17-21.
    [4] Shuler FD, Schlierf T, Wingate M (2014) Preventing falls with vitamin D. W V Med J 110: 10-12.
    [5] Beauchet O, Launay CP, Fantino B, et al. (2015) Motor imagery of gait in non-demented older community-dwellers: performance depends on serum 25-hydroxyvitamin D concentrations. Age (Dordr) 37: 18. doi: 10.1007/s11357-015-9755-3. doi: 10.1007/s11357-015-9755-3
    [6] Dawson-Hughes B (2012) Serum 25-hydroxyvitamin D and muscle atrophy in the elderly. Proc Nutr Soc 71: 46-49. doi: 10.1017/S0029665111003260. doi: 10.1017/S0029665111003260
    [7] Palvanen M, Kannus P, Piirtola M, et al. (2014) Effectiveness of the Chaos Falls Clinic in preventing falls and injuries of home-dwelling older adults: a randomised controlled trial. Injury 45: 265-271. doi: 10.1016/j.injury.2013.03.010 doi: 10.1016/j.injury.2013.03.010
    [8] Guo JL, Tsai YY, Liao JY, et al. (2014) Interventions to reduce the number of falls among older adults with/without cognitive impairment: an exploratory meta-analysis. Int J Geriatr Psychiatry 29: 661-669. doi: 10.1002/gps.4056. doi: 10.1002/gps.4056
    [9] Stubbs B, Brefka S, Denkinger MD (2015) What works to prevent falls in community-dwelling older adults? Umbrella review of meta-analyses of randomized controlled trials. Phys Ther 95: 1095-1110. doi: 10.2522/ptj.20140461.
    [10] Aung K (2014) Review: in postmenopausal women and older men, vitamin D plus calcium reduces some fractures. Ann Intern Med 161: JC5. doi: 10.7326/0003-4819-161-6-201409160-02005.
    [11] Muir SW, Montero-Odasso M (2011) Effect of vitamin D supplementation on muscle strength, gait and balance in older adults: a systematic review and meta-analysis. J Am Geriatr Soc 59: 2291-2300. doi: 10.1111/j.1532-5415.2011.03733.x. doi: 10.1111/j.1532-5415.2011.03733.x
    [12] Bischoff-Ferrari HA, Conzelmann M, Stähelin HB, et al. (2006) Is fall prevention by vitamin D mediated by a change in postural or dynamic balance? Osteoporos Int 17: 656-663. doi: 10.1007/s00198-005-0030-9
    [13] Korkmaz N, Tutoğlu A, Korkmaz I (2014) The relationships among vitamin D level, balance, muscle strength, and quality of life in postmenopausal patients with osteoporosis. J Phys Ther Sci 26: 1521-1526. doi: 10.1589/jpts.26.1521. doi: 10.1589/jpts.26.1521
    [14] Beauchet O, Annweiler C, Verghese J, et al. (2011) Biology of gait control: vitamin D involvement. Neurolog 76: 1617-1622. doi: 10.1212/WNL.0b013e318219fb08. doi: 10.1212/WNL.0b013e318219fb08
    [15] Dukas L, Schacht E, Runge M, et al. (2010) Effect of a six-month therapy with alfacalcidol on muscle power and balance and the number of fallers and falls. Arzneimittel forschung 60: 519-525. doi: 10.1055/s-0031-1296321.
    [16] Muschitz C, Kocijan R, Stütz V, et al. (2015) Vitamin D levels and comorbidities in ambulatory and hospitalized patients in Austria. Wien Klin Wochenschr 127: 675-684. doi:10.1007/s00508-015-0824-5. doi: 10.1007/s00508-015-0824-5
    [17] Pirotta S, Kidgell DJ, Daly RM (2015) Effects of vitamin D supplementation on neuroplasticity in older adults: a double-blinded, placebo-controlled randomised trial. Osteoporos Int 26: 131-140. doi: 10.1007/s00198-014-2855-6. doi: 10.1007/s00198-014-2855-6
    [18] Walrand S (2016) Effect of vitamin D on skeletal muscle. Geriatr Psychol Neuropsychiatr Vieil 21.
    [19] Iwamoto J, Sato Y (2014) Eldecalcitol improves chair-rising time in postmenopausal osteoporotic women treated with bisphosphonates. Ther Clin Risk Manag 10: 51-59. doi: 10.2147/TCRM.S54772.
    [20] Marcelli C, Chavoix C, Dargent-Molina P (2015) Beneficial effects of vitamin D on falls and fractures: is cognition rather than bone or muscle behind these benefits? Osteoporos Int 26: 1-10. doi: 10.1007/s00198-014-2829-8.
    [21] Annweiler C, Montero-Odasso M, Schott AM, et al. (2010) Fall prevention and vitamin D in the elderly: an overview of the key role of the non-bone effects. J Neuroeng Rehabil 17: v50. doi: 10.1186/1743-0003-7-50.
    [22] Takata S (2015) Active vitamin D3 analog. Nihon Rinsho 73: 1701-1705.
    [23] Saito K, Miyakoshi N, Matsunaga T, et al. (2016) Eldecalcitol improves muscle strength and dynamic balance in postmenopausal women with osteoporosis: an open-label randomized controlled study. J Bone Miner Metab 34: 547-554. doi: 10.1007/s00774-015-0695-x
    [24] Wihlborg A, Englund M, Åkesson K, et al. (2015) Fracture predictive ability of physical performance tests and history of falls in elderly women: a 10-year prospective study. Osteoporos Int 26: 2101-2109. doi: 10.1007/s00198-015-3106-1. doi: 10.1007/s00198-015-3106-1
    [25] Bird ML, Hill KD, Robertson I, et al. (2013) The association between seasonal variation in vitamin d, postural sway, and falls risk: an observational cohort study. J Aging Res 2013:751310. doi: 10.1155/2013/751310.
    [26] Matheï C, Van Pottelbergh G, Vaes B, et al. (2013) No relation between vitamin D status and physical performance in the oldest old: results from the Belfrail study. Age Ageing 42: 186-190. doi: 10.1093/ageing/afs186. doi: 10.1093/ageing/afs186
    [27] Boersma D, Demontiero O, Mohtasham Amiri Z, et al. (2012) Vitamin D status in relation to postural stability in the elderly. J Nutr Health Aging 16: 270-275. doi: 10.1007/s12603-011-0345-5
    [28] Krause M, Anschütz W, Vettorazzi E, et al. (2014) Vitamin D deficiency intensifies deterioration of risk factors, such as male sex and absence of vision, leading to increased postural body sway. Gait Posture 39: 166-171. doi: 10.1016/j.gaitpost.2013.06.017. doi: 10.1016/j.gaitpost.2013.06.017
    [29] Akdeniz S, Hepguler S, Öztürk C, et al. (2016) The relation between vitamin D and postural balance according to clinical tests and tetrax posturography. J Phys Ther Sci 28: 1272-1277. doi: 10.1589/jpts.28.1272. doi: 10.1589/jpts.28.1272
    [30] Sanyelbhaa H, Sanyelbhaa A (2015) Vestibular-evoked myogenic potentials and subjective visual vertical testing in patients with vitamin D deficiency/insufficiency. Eur Arch Otorhinolaryngol 272: 3233-329. doi: 10.1007/s00405-014-3395-6. doi: 10.1007/s00405-014-3395-6
    [31] Menant JC, Close JC, Delbaere K, et al. (2012) Relationships between serum vitamin D levels, neuromuscular and neuropsychological function and falls in older men and women. Osteoporos Int 23: 981-989. doi: 10.1007/s00198-011-1637-7. doi: 10.1007/s00198-011-1637-7
    [32] Uusi-Rasi K, Patil R, Karinkanta S, et al. (2015) Exercise and vitamin D in fall prevention among older women: a randomized clinical trial. JAMA Intern Med 175: 703-711. doi:10.1001/jamainternmed.2015.0225. doi: 10.1001/jamainternmed.2015.0225
    [33] Anek A, Bunyaratavej N, Jittivilai T (2015) Effects of short-term vitamin D supplementation on musculoskeletal and body balance for prevention of falling in postmenopausal women. J Med Assoc Thai 98 Suppl 8: S26-31.
    [34] Cangussu LM, Nahas-Neto J, Orsatti CL, et al. (2016) Effect of isolated vitamin D supplementation on the rate of falls and postural balance in postmenopausal women fallers: a randomized, double-blind, placebo-controlled trial. Menopause 23: 267-274. doi: 10.1097/GME.0000000000000525. doi: 10.1097/GME.0000000000000525
    [35] Tellioglu A, Basaran S, Guzel R, et al. (2012) Efficacy and safety of high dose intramuscular or oral cholecalciferol in vitamin D deficient/insufficient elderly. Maturitas 72: 332-338. doi: 10.1016/j.maturitas.2012.04.011. doi: 10.1016/j.maturitas.2012.04.011
    [36] Perin A, Zanatta E, Pigatto E, et al. (2012) Hypovitaminosis D in an hospitalized old population of Western Friuli. Reumatismo 64: 166-171. doi: 10.4081/reumatismo.2012.166.
    [37] Kirn DR, Koochek A, Reid KF, et al. (2015) The Vitality, Independence, and Vigor in the Elderly 2 Study (VIVE2): design and methods. Contemp Clin Trials 43: 164-171. doi:10.1016/j.cct.2015.06.001. doi: 10.1016/j.cct.2015.06.001
    [38] Schacht E, Ringe JD (2012) Alfacalcidol improves muscle power, muscle function and balance in elderly patients with reduced bone mass. Rheumatol Int 32: 207-215. doi: 10.1007/s00296-010-1607-y. doi: 10.1007/s00296-010-1607-y
    [39] Lips P, Binkley N, Pfeifer M, et al. (2010) Once-weekly dose of 8400 IU vitamin D(3) compared with placebo: effects on neuromuscular function and tolerability in older adults with vitamin D insufficiency. Am J Clin Nutr 91: 985-991. doi: 10.3945/ajcn.2009.28113. doi: 10.3945/ajcn.2009.28113
    [40] Rizzoli R, Boonen S, Brandi ML, et al. (2013) Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Curr Med Res Opin 29: 305-313. doi: 10.1185/03007995.2013.766162. doi: 10.1185/03007995.2013.766162
    [41] Dhesi JK, Jackson SH, Bearne LM, et al. (2004) Vitamin D supplementation improves neuromuscular function in older people who fall. Age Ageing 33: 589-595.
    [42] LeBlanc E, Chou R, Zakher B, et al. (2014) Screening for Vitamin D deficiency: systematic review for the U.S. Preventive Services Task Force Recommendation [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); Available from http://www.ncbi.nlm.nih.gov/books/NBK263419/.
    [43] Dawson-Hughes B (2012) Serum 25-hydroxyvitamin D and muscle atrophy in the elderly. Proc Nutr Soc 71: 46-49. doi: 10.1017/S0029665111003260.
    [44] Dhesi JK, Bearne LM, Moniz C, et al. (2002). Neuromuscular and psychomotor function in elderly subjects who fall and the relationship with vitamin D status. J Bone Min Res 17: 891-897. doi: 10.1359/jbmr.2002.17.5.891
    [45] Nakamura K, Oshiki R, Hatakeyama K, et al. (2006). Vitamin D status, postural sway, and the incidence of falls in elderly community-dwelling Japanese women. Arch Osteoporosis 1: 21-27.
    [46] Fujita T, Nakamura S, Ohue M, et al. (2007) Postural stabilizing effect of alfacalcidol algal calcium (AAA Ca) compared with calcium carbonate assessed by computerized posturography. J Bone Miner Metab 25: 68-73.
  • Reader Comments
  • © 2016 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(4458) PDF downloads(935) Cited by(0)

Article outline

Figures and Tables

Tables(2)

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog