Editorial Topical Sections

Dopamine and serotonin in fear extinction: some key questions to be addressed

  • Received: 23 May 2020 Accepted: 15 July 2020 Published: 22 July 2020
  • Citation: Carmelo M Vicario, Gabriella Martino. Dopamine and serotonin in fear extinction: some key questions to be addressed[J]. AIMS Neuroscience, 2020, 7(3): 271-274. doi: 10.3934/Neuroscience.2020014

    Related Papers:



  • 加载中


    Conflict of interest



    The authors declare that there are no conflicts of interest.

    [1] Vicario CM, Salehinejad MA, Felmingham K, et al. (2019) A systematic review on the therapeutic effectiveness of non-invasive brain stimulation for the treatment of anxiety disorders. Neurosci Biobehav Rev 96: 219-231. doi: 10.1016/j.neubiorev.2018.12.012
    [2] Martino G, Langher V, Cazzato V, et al. (2019) Editorial: Psychological factors as determinants of medical conditions. Front Psychol 10: 2502. doi: 10.3389/fpsyg.2019.02502
    [3] Martino G, Catalano A, Bellone F, et al. (2019) As time goes by: Anxiety negatively affects the perceived quality of life in patients with Type 2 diabetes of long duration. Front Psychol 10: 1779. doi: 10.3389/fpsyg.2019.01779
    [4] Martino G, Caputo A, Bellone F, et al. (2020) Going beyond the visible in type 2 diabetes mellitus: Defense mechanisms and their associations with depression and health-related quality of life. Front Psychol 11: 267. doi: 10.3389/fpsyg.2020.00267
    [5] Martino G, Bellone F, Langher V, et al. (2019) Alexithymia and psychological distress affect perceived quality of life in patients with type 2 diabetes mellitus. Mediterr J Clin Psychol 7: 1-15.
    [6] Rosa V, Tomai M, Lauriola M, et al. (2019) Body mass index, personality traits, and body image in Italian pre-adolescents: An opportunity for overweight prevention. Psihologija 52: 379-393. doi: 10.2298/PSI181121009R
    [7] Kalisch R, Gerlicher AMV, Duvarci S (2019) A dopaminergic basis for fear extinction. Trends Cogn Sci 23: 274-277. doi: 10.1016/j.tics.2019.01.013
    [8] Schultz W (2015) Neuronal reward and decision signals: From theories to data. Physiol Rev 95: 853-951. doi: 10.1152/physrev.00023.2014
    [9] Vicario CM, Gulisano M, Martino D, et al. (2016) Timing recalibration in childhood Tourette syndrome associated with persistent pimozide treatment. Neuropsychol 10: 211-222. doi: 10.1111/jnp.12064
    [10] Vicario CM, Gulisano M, Maugeri N, et al. (2020) Delay reward discounting in adolescents with Tourette's syndrome. Mov Disord (Online ahead of print).
    [11] Salinas-Hernández XI, Vogel P, Betz S, et al. (2018) Dopamine neurons drive fear extinction learning by signaling the omission of expected aversive outcomes. Elife 7: e38818. doi: 10.7554/eLife.38818
    [12] Luo R, Uematsu A, Weitemier A, et al. (2018) A dopaminergic switch for fear to safety transitions. Nat Commun 9: 2483. doi: 10.1038/s41467-018-04784-7
    [13] Porreca F, Navratilova E (2017) Reward, motivation, and emotion of pain and its relief. Pain 158: S43-S49. doi: 10.1097/j.pain.0000000000000798
    [14] Schultz W (2016) Dopamine reward prediction-error signalling: A two-component response. Nat Rev Neurosci 17: 183-195. doi: 10.1038/nrn.2015.26
    [15] Daw ND, Kakade S, Dayan P (2002) Opponent interactions between serotonin and dopamine. Neural Netw 15: 603-616. doi: 10.1016/S0893-6080(02)00052-7
    [16] Singewald N, Schmuckermair C, Whittle N, et al. (2015) Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther 149: 150-190. doi: 10.1016/j.pharmthera.2014.12.004
    [17] Vicario CM (2013) Uncovering the neurochemistry of reward and aversiveness. Front Mol Neurosci 19: 41.
    [18] Vicario CM, Nitsche MA, Felmingham K (2017) Forgetting fear associations through tES: Which memory process might be critical? Transl Psychiatry 7: e1046. doi: 10.1038/tp.2017.26
    [19] Wellman CL, Izquierdo A, Garrett JE, et al. (2007) Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. J Neurosci 27: 684-691. doi: 10.1523/JNEUROSCI.4595-06.2007
    [20] Zhang G, Ásgeirsdóttir HN, Cohen SJ, et al. (2013) Stimulation of serotonin 2A receptors facilitates consolidation and extinction of fear memory in C57BL/6J mice. Neuropharmacology 64: 403-413. doi: 10.1016/j.neuropharm.2012.06.007
    [21] Baratta MV, Kodandaramaiah SB, Monahan PE, et al. (2016) Stress enables reinforcement-elicited serotonergic consolidation of fear memory. Biol Psychiatry 79: 814-822. doi: 10.1016/j.biopsych.2015.06.025
    [22] Burghardt NS, Sigurdsson T, Gorman JM, et al. (2013) Chronic antidepressant treatment impairs the acquisition of fear extinction. Biol Psychiatry 73: 1078-1086. doi: 10.1016/j.biopsych.2012.10.012
    [23] Whittle N, Maurer V, Murphy C, et al. (2016) Enhancing dopaminergic signaling and histone acetylation promotes long-term rescue of deficient fear extinction. Transl Psychiatry 6: e974. doi: 10.1038/tp.2016.231
    [24] Maier SF, Seligman ME (2016) Learned helplessness at fifty: Insights from neuroscience. Psychol Rev 123: 349-367. doi: 10.1037/rev0000033
    [25] Deakin JFW (1983) Roles of brain serotonergic neurons in escape, avoidance and other behaviors. J Psychopharmacol 43: 563-577.
    [26] Ishiwata T, Hasegawa H, Greenwood BN (2017) Involvement of serotonin in the ventral tegmental area in thermoregulation of freely moving rats. Neurosci Lett 653: 71-77. doi: 10.1016/j.neulet.2017.05.030
    [27] Vicario CM, Nitsche MA, Hoysted I, et al. (2020) Anodal transcranial direct current stimulation over the ventromedial prefrontal cortex enhances fear extinction in healthy humans: A single blind sham-controlled study. Brain Stimul 13: 489-491. doi: 10.1016/j.brs.2019.12.022
  • Reader Comments
  • © 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(3376) PDF downloads(213) Cited by(2)

Article outline

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog