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AIMS Materials Science

2018, Volume 5, Issue 6: 1124-1140. doi: 10.3934/matersci.2018.6.1124
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Macro-, micro- and mesoporous materials for tissue engineering applications

  • 1.
    Tissue Bioengineering Laboratory, DEPeI-FO, Universidad Nacional Autónoma de México, Mexico
  • 2.
    Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Italy
  • Received: 17 September 2018 Accepted: 30 October 2018 Published: 19 November 2018

  • The design of three-dimensional materials with multiscale pore architecture currently represents a relevant challenge for tissue engineering. In the last three decades, degradable and resorbable biomaterials have been variously manipulated to generate macro/micro/mesoporous templates able to guide and facilitate basic cell activities concurring to the sequence of events triggering in vitro and in vivo regeneration of tissues. In this context, an accurate control of porosity features (i.e., pore size and distribution, pore interconnectivity) as a function of the peculiar properties of constituent materials is extremely demanded to not compromise scaffold mechanical properties and stability and replying local micro-environmental features from structural and functional point of view. Herein, an extended overview of consolidated and emerging approaches to design macro-, micro-, and mesoporous materials has been reported, underlining among differences mainly due to the peculiar properties of used biomaterials (i.e., polymers, ceramics, composites).

    Citation: Osmar Alejandro Chanes-Cuevas, Adriana Perez-Soria, Iriczalli Cruz-Maya, Vincenzo Guarino, Marco Antonio Alvarez-Perez. Macro-, micro- and mesoporous materials for tissue engineering applications[J]. AIMS Materials Science, 2018, 5(6): 1124-1140. doi: 10.3934/matersci.2018.6.1124

    Related Papers:

  • The design of three-dimensional materials with multiscale pore architecture currently represents a relevant challenge for tissue engineering. In the last three decades, degradable and resorbable biomaterials have been variously manipulated to generate macro/micro/mesoporous templates able to guide and facilitate basic cell activities concurring to the sequence of events triggering in vitro and in vivo regeneration of tissues. In this context, an accurate control of porosity features (i.e., pore size and distribution, pore interconnectivity) as a function of the peculiar properties of constituent materials is extremely demanded to not compromise scaffold mechanical properties and stability and replying local micro-environmental features from structural and functional point of view. Herein, an extended overview of consolidated and emerging approaches to design macro-, micro-, and mesoporous materials has been reported, underlining among differences mainly due to the peculiar properties of used biomaterials (i.e., polymers, ceramics, composites).


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