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AIMS Molecular Science

2023, Volume 10, Issue 2: 79-98. doi: 10.3934/molsci.2023007
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Review

Anti-inflammatory activity of natural coumarin compounds from plants of the Indo-Gangetic plain

  • 1.
    Department of Botany, Government General Degree College, Kharagpur II, P.O Madpur, Dist - Paschim Medinipur, Pin: 721149, West Bengal, India
  • 2.
    Department of Chemistry, Government General Degree College, Kharagpur II, P.O Madpur, Dist - Paschim Medinipur, Pin: 721149, West Bengal, India
  • 3.
    Department of Physiology, Government General Degree College, Kharagpur II, P.O Madpur, Dist - Paschim Medinipur, Pin: 721149, West Bengal, India
  • Received: 15 October 2022 Revised: 14 February 2023 Accepted: 05 March 2023 Published: 01 April 2023

  • Natural compounds are a repertoire of organoleptic molecules. This indicates that although they are not a significant source of nutrients, still they exhibit a wide range of medicinal properties through their plethora of anti-inflammatory and immune-modulatory activities. Coumarins, found in a variety of plants from different biodiversity regions, also have been reported to be present in many plants of the Indo-Gangetic plain. Here, we would attempt to enumerate the natural coumarin compounds, their pharmaco-therapeutic potential and their occurrence as well as abundance in the flora of the aforesaid biodiversity region. Coumarins, derived their name from the French word “coumarou” for Tonka bean. First isolated in 1820, coumarin still finds its relevance in the study of implementation of natural compounds in treating neuro-degenerative and cancer-like fatal diseases. Naturally occurring benzopyrones, chemically classified as lactones and coumarin compounds need to be reviewed to develop new era drugs from natural resources. This promises an effective treatment regimen with minimal side effects and also paves the path for a sustainable future with efforts to manage our health problems from the plant products in our immediate environment.

    Citation: Ramkrishna Ghosh, Partha Sarathi Singha, Lakshmi Kanta Das, Debosree Ghosh, Syed Benazir Firdaus. Anti-inflammatory activity of natural coumarin compounds from plants of the Indo-Gangetic plain[J]. AIMS Molecular Science, 2023, 10(2): 79-98. doi: 10.3934/molsci.2023007

    Related Papers:

  • Natural compounds are a repertoire of organoleptic molecules. This indicates that although they are not a significant source of nutrients, still they exhibit a wide range of medicinal properties through their plethora of anti-inflammatory and immune-modulatory activities. Coumarins, found in a variety of plants from different biodiversity regions, also have been reported to be present in many plants of the Indo-Gangetic plain. Here, we would attempt to enumerate the natural coumarin compounds, their pharmaco-therapeutic potential and their occurrence as well as abundance in the flora of the aforesaid biodiversity region. Coumarins, derived their name from the French word “coumarou” for Tonka bean. First isolated in 1820, coumarin still finds its relevance in the study of implementation of natural compounds in treating neuro-degenerative and cancer-like fatal diseases. Naturally occurring benzopyrones, chemically classified as lactones and coumarin compounds need to be reviewed to develop new era drugs from natural resources. This promises an effective treatment regimen with minimal side effects and also paves the path for a sustainable future with efforts to manage our health problems from the plant products in our immediate environment.


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    Acknowledgments


    RG acknowledges the Department of Botany, Govt. General Degree College, Kharagpur II West Bengal, India. Dr. PSS and Dr. LKD acknowledge the Department of Chemistry, Govt. General Degree College, Kharagpur II West Bengal, India. Dr. DG and Dr. SBF acknowledge the Department of Physiology, Govt. General Degree College, Kharagpur II West Bengal, India.

    Conflict of Interests


    We declare no conflicts of interest in the paper.

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