Migraine, affecting over 1.04 billion people globally, is a severe, recurrent headache disorder with significant impacts on life quality. Despite extensive research on risk factors, the association with cutaneous allodynia (CA) is underexplored.
This study aims to assess the predictors contributing to both cutaneous allodynia (CA) and migraine and their prevalence among primary healthcare (PHC) visitors in Madinah City, Saudi Arabia.
A total of 403 participants agreed to participate in our cross-sectional study between September 1, 2023, and November 1, 2023. Migraine screening questionnaire (MS-Q) was used to screen for migraine. To assess allodynia symptoms, we used Allodynia Symptoms Checklist-12 (ASC-12). Participants aged 15 and older who attended one of the major PHC centers in Madinah City were included in the study.
The prevalence of migraine among the participants was found to be 16.4%, with 57.6% of migraine patients exhibiting CA symptoms. Family history of migraine and high BMI were identified as significant predictors of migraine (P < 0.05), with odds ratio (OR) of 5.7 and 1.1, respectively. Additionally, female sex and high BMI were significant (P < 0.05) risk factors for CA among migraine patients, with ORs of 4.3 and 1.1, respectively.
The prevalence of migraine in Madinah City was higher than the global average but lower than the national average. A significant proportion of migraine patients also experienced CA. Further research is warranted to elucidate the underlying mechanisms of migraine and CA, which could aid the development of targeted treatments and improve patient outcomes.
Citation: Mohammed Qarah, Noura Alshammari, Ali Alsolami, Ahmed Abualkhair, Abdulaziz Aloufi, Anas Alzhrani, Shatha Almuyidi, Mayada Almohandes. Cutaneous allodynia association with migraine and their predictors among primary healthcare visitors[J]. AIMS Medical Science, 2024, 11(4): 452-463. doi: 10.3934/medsci.2024031
Migraine, affecting over 1.04 billion people globally, is a severe, recurrent headache disorder with significant impacts on life quality. Despite extensive research on risk factors, the association with cutaneous allodynia (CA) is underexplored.
This study aims to assess the predictors contributing to both cutaneous allodynia (CA) and migraine and their prevalence among primary healthcare (PHC) visitors in Madinah City, Saudi Arabia.
A total of 403 participants agreed to participate in our cross-sectional study between September 1, 2023, and November 1, 2023. Migraine screening questionnaire (MS-Q) was used to screen for migraine. To assess allodynia symptoms, we used Allodynia Symptoms Checklist-12 (ASC-12). Participants aged 15 and older who attended one of the major PHC centers in Madinah City were included in the study.
The prevalence of migraine among the participants was found to be 16.4%, with 57.6% of migraine patients exhibiting CA symptoms. Family history of migraine and high BMI were identified as significant predictors of migraine (P < 0.05), with odds ratio (OR) of 5.7 and 1.1, respectively. Additionally, female sex and high BMI were significant (P < 0.05) risk factors for CA among migraine patients, with ORs of 4.3 and 1.1, respectively.
The prevalence of migraine in Madinah City was higher than the global average but lower than the national average. A significant proportion of migraine patients also experienced CA. Further research is warranted to elucidate the underlying mechanisms of migraine and CA, which could aid the development of targeted treatments and improve patient outcomes.
Cutaneous allodynia
Primary healthcare
Years lived with disability
Migraine screening questionnaire
Allodynia Symptoms Checklist-12
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Mohammed Qarah, Noura Alshammari, Ali Alsolami, Ahmed Abualkhair, Abdulaziz Aloufi, Anas Alzhrani, Shatha Almuyidi, Mayada Almohandes. Cutaneous allodynia association with migraine and their predictors among primary healthcare visitors[J]. AIMS Medical Science, 2024, 11(4): 452-463. doi: 10.3934/medsci.2024031
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