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AIMS Medical Science

2022, Volume 9, Issue 1: 65-80. doi: 10.3934/medsci.2022007
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Anaphylaxis: recognition, treatment, and outcomes

  • 1.
    Children's Hospital of Michigan, Detroit, Central Michigan University, MI, USA
  • 2.
    UT Health Sciences Center San Antonio, San Antonio, TX, USA
  • Received: 14 December 2021 Revised: 10 March 2022 Accepted: 11 March 2022 Published: 18 March 2022

  • Anaphylaxis is defined as an acute, life-threatening, systemic allergic reaction associated with a broad array of clinical manifestations. Anaphylaxis typically is a type 1 (IgE mediated) hypersensitivity reaction though other mechanism may also be involved. Patients most commonly present with cutaneous symptoms followed by respiratory and gastrointestinal symptoms. Prompt recognition and treatment can be life saving. Epinephrine is the drug of choice for treatment of anaphylaxis. It is imperative that patients and their caregivers are educated on the use of epinephrine autoinjectors and provided with an emergency action plan for managing anaphylaxis.

    Citation: Divya Seth, Deepak Kamat. Anaphylaxis: recognition, treatment, and outcomes[J]. AIMS Medical Science, 2022, 9(1): 65-80. doi: 10.3934/medsci.2022007

    Related Papers:

  • Anaphylaxis is defined as an acute, life-threatening, systemic allergic reaction associated with a broad array of clinical manifestations. Anaphylaxis typically is a type 1 (IgE mediated) hypersensitivity reaction though other mechanism may also be involved. Patients most commonly present with cutaneous symptoms followed by respiratory and gastrointestinal symptoms. Prompt recognition and treatment can be life saving. Epinephrine is the drug of choice for treatment of anaphylaxis. It is imperative that patients and their caregivers are educated on the use of epinephrine autoinjectors and provided with an emergency action plan for managing anaphylaxis.

    Abbreviations

    AAAAI

    American Academy of Allergy, Asthma, and Immunology

         ACE

    Angiotensin converting enzyme

         AIE

    Auto-injectable epinephrine

         BP

    Blood pressure

         CGRP

    Calcitonin gene-related peptide

         CT

    Computerized tomography

         EEG

    Electroencephalogram

         EIA

    Exercise induced anaphylaxis

         EKG

    Electrocardiogram

         ER

    Emergency room

         HAE

    Hereditary angioedema

         HCP

    Health care professional

         Ig

    Immunoglobulin

         MCT

    Mast cell tryptase

         NSAIDs

    Non-steroidal anti-inflammatory drugs

         PAF

    Platelet Activating Factor

         RCM

    Radio-contrast media

         TNF

    Tumor necrosis factor

         US

    United States

         USP

    United States Pharmacopeia

         UV

    Ultra-violet

         VCD

    Vocal Cord Dysfunction

         WAO

    World Allergy Organization
    加载中


    Conflict of interest


    The authors declare no relevant conflict of interest.

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