Research article

Effectiveness of germinated brown rice on metabolic syndrome: A randomized control trial in Vietnam

  • Received: 23 October 2019 Accepted: 08 January 2020 Published: 17 January 2020
  • To treating Metabolic Syndrome (MetS) in the human body by using cooked pre-germinated brown rice (PGBR), a randomized control trial was done in Vietnam. 80 subjects (65.1 ± 3.81 years old) separated into two groups in pairs were assigned a daily intake of 200 g PGBR, and the subjects in the placebo group were kept in normal living ways (consuming white rice). Before baseline and after 3 months of the intervention, anthropometric measurements, blood chemical examinations, a nutrition survey, and physical activity measurements were conducted. The main finding showed that the percentages of patients with MetS in the PGBR group were reduced significantly compared to the placebo group (p < 0.05). Serum HDL cholesterol concentrations were significantly increased from 1.11 (mmol/l) to 1.44 (mmol/l) compared to the placebo group (p < 0.05). The findings suggest that PGBR may affect HDL cholesterol, PGBR might be considered in reducing the risk of MetS in Vietnam.

    Citation: Truong Tuyet Mai, Tran Thu Trang, Tran Thi Hai. Effectiveness of germinated brown rice on metabolic syndrome: A randomized control trial in Vietnam[J]. AIMS Public Health, 2020, 7(1): 33-43. doi: 10.3934/publichealth.2020005

    Related Papers:

  • To treating Metabolic Syndrome (MetS) in the human body by using cooked pre-germinated brown rice (PGBR), a randomized control trial was done in Vietnam. 80 subjects (65.1 ± 3.81 years old) separated into two groups in pairs were assigned a daily intake of 200 g PGBR, and the subjects in the placebo group were kept in normal living ways (consuming white rice). Before baseline and after 3 months of the intervention, anthropometric measurements, blood chemical examinations, a nutrition survey, and physical activity measurements were conducted. The main finding showed that the percentages of patients with MetS in the PGBR group were reduced significantly compared to the placebo group (p < 0.05). Serum HDL cholesterol concentrations were significantly increased from 1.11 (mmol/l) to 1.44 (mmol/l) compared to the placebo group (p < 0.05). The findings suggest that PGBR may affect HDL cholesterol, PGBR might be considered in reducing the risk of MetS in Vietnam.



    加载中

    Acknowledgments



    Thanks for the support from Loc Troi Company who provided the PGBR samples. This study was financially supported by the National Institute of Nutrition, Vietnam.

    Conflict of interests



    The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

    [1] Lin YC, Yang CC, Chen YJ, et al. (2012) Utilization of statins and aspirin among patients with diabetes and hyperlipidemia: Taiwan, 1998–2006. J Chinese Med Assoc 75: 567-572. doi: 10.1016/j.jcma.2012.08.020
    [2] Ginter E, Simko V (2012) Global prevalence and future of diabetes mellitus. Adv Exp Med Biol 771: 35-41. doi: 10.1007/978-1-4614-5441-0_5
    [3] Connor WE, Duell PB, Connor SL (2005) Benefits and hazards of dietary carbohydrate. Curr Atheroscler Rep 7: 428-434. doi: 10.1007/s11883-005-0059-4
    [4] Zhang PY (2014) Cardiovascular disease in diabetes. Eur Rev Med Pharmacol Sci 18: 2205-2214.
    [5] Iwamoto M, Yagi K, Yazumi K, et al. (2013) Eating a healthy lunch improves serum alanine aminotransferase activity. Lipids Health Dis 12: 134. doi: 10.1186/1476-511X-12-134
    [6] Komindr S, Ingsriswang S, Lerdvuthisopon N, et al. (2001) Effect of long-term intake of Asian food with different glycemic indices on diabetic control and protein conservation in type 2 diabetic patients. J Med Assoc Thai 84: 85-97.
    [7] Van Rompay MI, McKeown NM, Castaneda-Sceppa C, et al. (2012) Carbohydrate nutrition differs by diabetes status and is associated with dyslipidemia in Boston puerto rican adults without diabetes. J Nutr 143: 182-188. doi: 10.3945/jn.112.168914
    [8] Hsu TF, Kise M, Wang MF, et al. (2008) Effects of pre-germinated brown rice on blood glucose and lipid levels in free-living patients with impaired fasting glucose or type 2 diabetes. J Nutr Sci Vitaminol (Tokyo) 54: 163-168. doi: 10.3177/jnsv.54.163
    [9] Bui TN, Le TH, Nguyen DH, et al. (2014) Pre-germinated brown rice reduced both blood glucose concentration and body weight in Vietnamese women with impaired glucose tolerance. J Nutr Sci Vitaminol (Tokyo) 60: 183-187. doi: 10.3177/jnsv.60.183
    [10] Shen KP, Hao CL, Yen HW, et al. (2015) Pre-germinated brown rice prevents hight-fat diet induced hyperglycemia through elevated insulin secretion and glucose metabolism pathway in C57BL/6J strain mice. J Clin Biochem Nutr 56: 28-34. doi: 10.3164/jcbn.14-50
    [11] Nhung BT, Tuyen LD, Linh VA, et al. (2016) Rice bran extract reduces the risk of atherosclerosis in post-menopausal Vietnamese women. J Nutr Sci Vitaminol (Tokyo) 62: 295-302. doi: 10.3177/jnsv.62.295
    [12] National Institute of Nutrition (2007)  Vietnamese Food Composition Table. Vol 2. Available from: http://www.fao.org/fileadmin/templates/food_composition/documents/pdf/VTN_FCT_2007.pdf.
    [13] (2009) World Health OrganizationGlobal Recommendations on Physical Activity for Health.WHO. Available from: https://apps.who.int/iris/bitstream/handle/10665/44399/9789241599979_eng.pdf?s
    [14] Shimabukuo M, Higa M, Kinjo R, et al. (2014) Effects of the brown rice diet on visceral obesity and endothelial function: The BRAVO study. Br J Nutr 111: 310-320. doi: 10.1017/S0007114513002432
    [15] Ito Y, Nakashima Y, Matsuoka S (2015) Rice bran extract containing acylated steryl glucoside fraction decreases elevated blood LDL cholesterol level in obese Japanese men. J Med Invest 62: 80-84. doi: 10.2152/jmi.62.80
    [16] Hu EA, Pan A, Malik V, et al. (2012) White rice consumption and risk of type 2 diabetes: Meta-analysis and systematic review. BMJ 344: e1454. doi: 10.1136/bmj.e1454
    [17] Sun Q, Spiegelman D, van Dam RM, et al. (2010) White rice, brown rice, and risk of type 2 diabetes in US men and women. Arch Intern Med 170: 961-969. doi: 10.1001/archinternmed.2010.109
    [18] Kløve B, Heikkinen K, Mander Ü, et al. (2010)  Summary Report: Gerenal Nutrition Survey 2009–2010. Available from: http://viendinhduong.vn/FileUpload/Documents/Summary_report_gns_2009-2010_chuan.PDF.
    [19] Imam MU, Ismail M (2013) Nutrigenomic effects of germinated brown rice and its bioactives on hepatic gluconeogenic genes in type 2 diabetic rats and HEPG2 cells. Mol Nutr Food Res 57: 401-411. doi: 10.1002/mnfr.201200429
    [20] Weickert MO (2018) High fiber intake, dietary protein, and prevention of type 2 diabetes. Expert Rev Endocrinol Metab 13: 223-224. doi: 10.1080/17446651.2018.1513320
    [21] Jovanovski E, Khayyat R, Zurbau A, et al. (2019) Should viscous fiber supplements be considered in diabetes control? Results from a systematic review and meta-analysis of randomized controlled trials. Diabetes Care 42: 755-766. doi: 10.2337/dc18-1126
  • Reader Comments
  • © 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(3839) PDF downloads(410) Cited by(9)

Article outline

Figures and Tables

Tables(5)

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog