Intracellular signaling often employs excitable stores of calcium
coupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gates
for computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors for
biological signals.
Citation: H. G. E. Hentschel, Alan Fine, C. S. Pencea. Biological computing with diffusion and excitable calcium stores[J]. Mathematical Biosciences and Engineering, 2004, 1(1): 147-159. doi: 10.3934/mbe.2004.1.147
Abstract
Intracellular signaling often employs excitable stores of calcium
coupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gates
for computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors for
biological signals.