Emerging polymeric materials in additive manufacturing for use in biomedical applications

A. Sydney Gladman; Manuel Garcia-Leiner; Alexis F. Sauer-Budge; A. Sydney Gladman; Manuel Garcia-Leiner; Alexis F. Sauer-Budge

doi:10.3934/bioeng.2019.1.1

AIMS Bioengineering

2019, Volume 6, Issue 1: 1-20. doi: 10.3934/bioeng.2019.1.1

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Review Special Issues

Emerging polymeric materials in additive manufacturing for use in biomedical applications

Polymer Science and Materials Chemistry, Exponent, Inc. 9 Strathmore Rd., Natick, MA USA

Received: 21 December 2018 Accepted: 14 February 2019 Published: 26 February 2019

Additive manufacturing is poised to enable the next biomedical revolution, where customized, patient-specific tools, therapies, pharmaceuticals, and even replacement organs are taking strides in the biomedical research and development space. Polymeric materials are capable of making inroads in a wide variety of biomedical applications, and in recent years a growing number are being used with additive manufacturing techniques. This review highlights some of the emerging classes of polymers used in additive manufacturing and examples of their use in biomedical applications, with a focus on the delineation of ‘hard’ polymers versus ‘soft’ polymers and the specific applications where they are utilized.
- additive manufacturing,
- polymers,
- biomedical applications
Citation: A. Sydney Gladman, Manuel Garcia-Leiner, Alexis F. Sauer-Budge. Emerging polymeric materials in additive manufacturing for use in biomedical applications[J]. AIMS Bioengineering, 2019, 6(1): 1-20. doi: 10.3934/bioeng.2019.1.1

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Abstract

Additive manufacturing is poised to enable the next biomedical revolution, where customized, patient-specific tools, therapies, pharmaceuticals, and even replacement organs are taking strides in the biomedical research and development space. Polymeric materials are capable of making inroads in a wide variety of biomedical applications, and in recent years a growing number are being used with additive manufacturing techniques. This review highlights some of the emerging classes of polymers used in additive manufacturing and examples of their use in biomedical applications, with a focus on the delineation of ‘hard’ polymers versus ‘soft’ polymers and the specific applications where they are utilized.

Abbreviation AM: Additive manufacturing; 3DP: Three-dimensional printing; FDA: United States Food and Drug Administration; SLS: selective laser sintering; SLA: stereolithography; CLIP: Continuous Liquid Interface Production; FDM: fused deposition modeling; PEKK: polyetherketoneketone; PAEK: polyaryletherketone; PEEK: polyetheretherketone; PCL: polycaprolactone; PGA: poly(glycolic acid); PLA: polylactic acid; PDO: polydioxanone; PEG: polyethylene glycol; GelMA: gelatin methacrylol; MeHA: methacrylated hyaluronic acid; PDMS: polydimethylsiloxane; MRI: magnetic resonance imaging; CT: computed tomography; RGD: arginylglycylaspartic acid; PDMS: polydimethylsiloxane;

Conflict of interest

All authors declare no conflicts of interest in this paper.

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