Manuscript Topics

The body surfaces are the entrance door whereby the invasive agents, pathogen or not, gain access. For this reason, all living organisms place their first defensive line, consisting of a mixture of specific and nonspecific immune mechanisms which are capable of solving the majority of the invasive attempts at the mucosal level. The mucosal associated lymphoid tissue (MALT) is able to catch antigens at this level, thus preserving from many of the pathogens that enter through mucus membranes. The best known tissues are the GALT (gut-associated lymphoid tissue) and the BALT (bronchi-associated lymphoid tissue).

On the other hand, great efforts are recently being devoted to the development of vaccines that stimulate mucus membranes, instead of using intramuscular or subcutaneous routes of administration, because mucosae are the usual route of colonization where the infectious process begins. One of its advantages is that mucosal immunity is developed much sooner than systemic immune responses, thus allowing vaccination at more early stages than it is applied nowadays to any living organism.

On the basis of these antecedents, we would like to invite authors to submit original research and/or review articles focused on any mechanism concerning mucosal immunity. Potential topics could include, but are not restricted to

• Studies about mucosal immunity located on gastrointestinal tract (GALT)
• Studies about mucosal immunity located on respiratory tract (BALT)
• Studies about mucosal immunity located in other organic tissue
• Studies about any of the cells implied in mucosal immunity (naïve B-cells, dendritic cells, γδ T-cells…)
• Use of adjuvants boosting mucosal antigens
• Vaccines based on live organisms being applied by mucosal route

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