Citation: Andrés Molero-Chamizo, Guadalupe Nathzidy Rivera-Urbina. Molecular mechanisms involved in taste learning and memory[J]. AIMS Molecular Science, 2017, 4(4): 389-398. doi: 10.3934/molsci.2017.4.389
[1] | Scott TR (2011) Learning through the taste system. Front Syst Neurosci 5: 87. |
[2] | Yamamoto T, Ueji K (2011) Brain mechanisms of flavor learning. Front Syst Neurosci 5: 76. |
[3] | Bermúdez-Rattoni F, McGaugh JL (1991) Insular cortex and amygdala lesions differentially affect acquisition of inhibitory avoidance and conditioned taste aversion. Brain Res 549: 165-170. doi: 10.1016/0006-8993(91)90616-4 |
[4] | Lin JY, Arthurs J, Reilly S (2015) Gustatory insular cortex, aversive taste memory and taste neophobia. Neurobiol Learn Mem 119: 77-84. doi: 10.1016/j.nlm.2015.01.005 |
[5] | Stehberg J, Moraga-Amaro R, Simon F (2011) The role of the insular cortex in taste function. Neurobiol Learn Mem 96: 130-135. doi: 10.1016/j.nlm.2011.03.005 |
[6] | Reilly S, Bornovalova MA (2005) Conditioned taste aversion and amygdala lesions in the rat: a critical review. Neurosci Biobehav Rev 29: 1067-1088. doi: 10.1016/j.neubiorev.2005.03.025 |
[7] | Bermúdez-Rattoni F, Ramírez-Lugo L, Gutiérrez R, et al. (2004) Molecular signals into the insular cortex and amygdala during aversive gustatory memory formation. Cell Mol Neurobiol 24: 25-36. doi: 10.1023/B:CEMN.0000012722.45805.c8 |
[8] | Miranda MI, McGaugh JL (2004) Enhancement of inhibitory avoidance and conditioned taste aversion memory with insular cortex infusions of 8-Br-cAMP: involvement of the basolateral amygdala. Learn Mem 11: 312-317. doi: 10.1101/lm.72804 |
[9] | Schafe GE, Bernstein IL (1996) Forebrain contribution to the induction of a brainstem correlate of conditioned taste aversion: I. The amygdala. Brain Res 741: 109-116. doi: 10.1016/S0006-8993(96)00906-7 |
[10] | Sakai N, Yamamoto T (1999) Possible routes of visceral information in the rat brain in formation of conditioned taste aversion. Neurosci Res 35: 53-61. doi: 10.1016/S0168-0102(99)00067-X |
[11] | Tokita K, Karádi Z, Shimura T, et al. (2004) Centrifugal inputs modulate taste aversion learning associated parabrachial neuronal activities. J Neurophysiol 92: 265-279. doi: 10.1152/jn.01090.2003 |
[12] | Clark EW, Bernstein IL (2009) Establishing aversive, but not safe, taste memories requires lateralized pontine-cortical connections. Behav Brain Res 197: 356-363. doi: 10.1016/j.bbr.2008.09.030 |
[13] | Spray KJ, Bernstein IL (2004) Afferent and efferent connections of the parvicellular subdivision of iNTS: defining a circuit involved in taste aversion learning. Behav Brain Res 154: 85-97. doi: 10.1016/j.bbr.2004.01.027 |
[14] | Molero-Chamizo A (2017) Modulation of the magnitude of conditioned taste aversion in rats with excitotoxic lesions of the basolateral amygdala. Neurobiol Learn Mem 137: 56-64. doi: 10.1016/j.nlm.2016.11.009 |
[15] | Dayawansa S, Ruch S, Norgren (2014) Parabrachial-hypothalamic interactions are required for normal conditioned taste aversions. Am J Physiol Regul Integr Comp Physiol 306: R190-200. doi: 10.1152/ajpregu.00333.2013 |
[16] | Bielavska E, Roldan G (1996) Ipsilateral connections between the gustatory cortex, amygdala and parabrachial nucleus are necessary for acquisition and retrieval of conditioned taste aversion in rats. Behav Brain Res 81: 25-31. doi: 10.1016/S0166-4328(96)00039-3 |
[17] | Yamamoto T, Sako N, Sakai N, et al. (1997) Gustatory and visceral inputs to the amygdala of the rat: conditioned taste aversion and induction of c-fos-like immunoreactivity. Neurosci Lett 226: 127-130. doi: 10.1016/S0304-3940(97)00265-6 |
[18] | St Andre J, Reilly S (2007). Effects of central and basolateral amygdala lesions on conditioned taste aversion and latent inhibition. Behav Neurosci 121: 90-99. doi: 10.1037/0735-7044.121.1.90 |
[19] | Koh MT, Bernstein IL (2005). Mapping conditioned taste aversion associations using c-Fos reveals a dynamic role for insular cortex. Behav Neurosci 119: 388-398. doi: 10.1037/0735-7044.119.2.388 |
[20] | Harrer MI, Travers SP (1996) Topographic organization of Foslike immunoreactivity in the rostral nucleus of the solitary tract evoked by gustatory stimulation with sucrose and quinine. Brain Res 711: 125-137. doi: 10.1016/0006-8993(95)01410-1 |
[21] | Marotta R, Fenu S, Scheggi S, et al. (2014) Acquisition and expression of conditioned taste aversion differentially affects extracellular signal regulated kinase and glutamate receptor phosphorylation in rat prefrontal cortex and nucleus accumbens. Front Behav Neurosci 8: 153. |
[22] | Lunceford BE, Kubanek J (2015) Reception of Aversive Taste. Integr Comp Biol 55: 507-517. |
[23] | Inberg S, Jacob E, Elkobi A, et al. (2016) Fluid consumption and taste novelty determines transcription temporal dynamics in the gustatory cortex. Mol Brain 9: 13. doi: 10.1186/s13041-016-0188-4 |
[24] | Miranda I, Ferreira G, Ramı́ L, et al. (2003) Role of cholinergic system on the construction of memories: taste memory encoding. Neurobiol Learn Mem 80: 211-222. doi: 10.1016/S1074-7427(03)00061-3 |
[25] | Stern E, Chinnakkaruppan A, David O, et al. (2013) Blocking the eIF2α kinase (PKR) enhances positive and negative forms of cortexdependent taste memory. J Neurosci 33: 2517-2525. |
[26] | Gal-Ben-Ari S, Rosenblum K (2012) Molecular mechanisms underlying memory consolidation of taste information in the cortex. Front Behav Neurosci 5: 87. |
[27] | Elkobi A, Ehrlich I, Belelovsky K, et al. (2008) ERKdependent PSD-95 induction in the gustatory cortex is necessary for taste learning, but not retrieval. Nat Neurosci 11: 1149-1151. doi: 10.1038/nn.2190 |
[28] | Rosenblum K, Meiri N, Dudai Y (1993) Taste memory: the role of protein synthesis in gustatory cortex. Behav Neural Biol 59: 49-56. doi: 10.1016/0163-1047(93)91145-D |
[29] | Merhav M, Rosenblum K (2008) Facilitation of taste memory acquisition by experiencing previous novel taste is protein-synthesis dependent. Learn Mem 15: 501-507. |
[30] | Levitan D, Gal-Ben-Ari S, Heise C, et al. (2016) The differential role of cortical protein synthesis in taste memory formation and persistence. NPJ Sci Learn 1:16001. doi: 10.1038/npjscilearn.2016.1 |
[31] | Okuno H (2011) Regulation and function of immediate-early genes in the brain: beyond neuronal activity markers. Neurosci Res 69: 175-186. doi: 10.1016/j.neures.2010.12.007 |
[32] | Plath N, Ohana O, Dammermann B, et al. (2006) Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron 52: 437-444. |
[33] | Inberg S, Elkobi A, Edri E, et al. (2013) Taste familiarity is inversely correlated with Arc/Arg3.1 hemispheric lateralization. J Neurosci 33: 11734-11743. |
[34] | Rosenblum K, Meiri N, Dudai Y (1993) Taste memory: the role of protein synthesis in gustatory cortex. Behav Neural Biol 59: 49-56. doi: 10.1016/0163-1047(93)91145-D |
[35] | Rivera-Olvera A, Rodríguez-Durán LF, Escobar ML (2016) Conditioned taste aversion prevents the long-lasting BDNF-induced enhancement of synaptic transmission in the insular cortex: A metaplastic effect. Neurobiol Learn Mem 130: 71-76. doi: 10.1016/j.nlm.2016.01.014 |
[36] | Doron G, Rosenblum K (2010) c-Fos expression is elevated in GABAergic interneurons of the gustatory cortex following novel taste learning. Neurobiol Learn Mem 94: 21-29. doi: 10.1016/j.nlm.2010.03.003 |
[37] | Saddoris MP, Holland PC, Gallagher M (2009) Associatively learned representations of taste outcomes activate taste-encoding neural ensembles in gustatory cortex. J Neurosci 29: 15386-15396. |
[38] | Berman DE (2003) Modulation of taste-induced Elk-1 activation by identified neurotransmitter systems in the insular cortex of the behaving rat. Neurobiol Learn Mem 79: 122-126. doi: 10.1016/S1074-7427(02)00017-5 |
[39] | Bermúdez-Rattoni F (2004) Molecular mechanisms of taste-recognition memory. Nat Rev Neurosci 5: 209-217. doi: 10.1038/nrn1344 |
[40] | Berman DE, Hazvi S, Neduva V, et al. (2000) The role of identified neurotransmitter systems in the response of insular cortex to unfamiliar taste: activation of ERK1-2 and formation of a memory trace. J Neurosci 20: 7017-7023. |
[41] | Parkes SL, De la Cruz V, Bermúdez-Rattoni F, et al. (2014) Differential role of insular cortex muscarinic and NMDA receptors in one-trial appetitive taste learning. Neurobiol Learn Mem 116: 112-116. doi: 10.1016/j.nlm.2014.09.008 |
[42] | Rodríguez-García G, Miranda MI (2016) Opposing Roles of Cholinergic and GABAergic Activity in the Insular Cortex and Nucleus Basalis Magnocellularis during Novel Recognition and Familiar Taste Memory Retrieval. J Neurosci 36: 1879-1889. doi: 10.1523/JNEUROSCI.2340-15.2016 |
[43] | Rosenblum K, Berman DE, Hazvi S, et al. (1997) NMDA receptor and the tyrosine phosphorylation of its 2B subunit in taste learning in the rat insular cortex. J Neurosci 17: 5129-5135. |
[44] | David O, Barrera I, Chinnakkaruppan A, et al. (2014) Dopamine-induced tyrosine phosphorylation of NR2B (Tyr1472) is essential for ERK1/2 activation and processing of novel taste information. Front Mol Neurosci 7: 66. |
[45] | Nuñez-Jaramillo L, Jiménez B, Luna-Illades N, et al. (2003) Serine phosphorylation of the NMDA receptor subunits NR2A and NR2B in the insular cortex is related with taste recognition memory. J Neurochem 87: 73. |
[46] | Marotta R, Fenu S, Scheggi S, et al. (2014) Acquisition and expression of conditioned taste aversion differentially affects extracellular signal regulated kinase and glutamate receptor phosphorylation in rat prefrontal cortex and nucleus accumbens. Front Behav Neurosci 8: 153. |
[47] | Adaikkan C, Rosenblum K (2015) A molecular mechanism underlying gustatory memory trace for an association in the insular cortex. Elife 4: e07582. |
[48] | Rodríguez-Durán LF, Escobar ML (2014) NMDA receptor activation and PKC but not PKA lead to the modification of the long-term potentiation in the insular cortex induced by conditioned taste aversion: differential role of kinases in metaplasticity. Behav Brain Res 266: 58-62. |
[49] | Bermudez-Rattoni F (2014) The forgotten insular cortex: its role on recognition memory formation. Neurobiol Learn Mem 109: 207-216. doi: 10.1016/j.nlm.2014.01.001 |
[50] | Rosenberg T, Elkobi A, Rosenblum K (2016) mAChR-dependent decrease in proteasome activity in the gustatory cortex is necessary for novel taste learning. Neurobiol Learn Mem 135: 115-124. doi: 10.1016/j.nlm.2016.07.029 |
[51] | Rosenberg T, Elkobi A, Dieterich DC, et al. (2016) NMDAR-dependent proteasome activity in the gustatory cortex is necessary for conditioned taste aversion. Neurobiol Learn Mem 130: 7-16. doi: 10.1016/j.nlm.2016.01.002 |
[52] | Gómez-Chacón B, Gámiz F, Foster TC, et al. (2016) Increased N-Ethylmaleimide-Sensitive Factor Expression in Amygdala and Perirhinal Cortex during Habituation of Taste Neophobia. Neural Plast 2016: 2726745. |
[53] | Rodríguez-Serrano LM, Ramírez-León B, Rodríguez-Durán LF, et al. (2014) Acute infusion of brain-derived neurotrophic factor in the insular cortex promotes conditioned taste aversion extinction. Neurobiol Learn Mem 116: 139-144. doi: 10.1016/j.nlm.2014.10.007 |
[54] | Martínez-Moreno A, Rodríguez-Durán LF, Escobar ML (2011) Late protein synthesis-dependent phases in CTA long-term memory: BDNF requirement. Front Behav Neurosci 5: 61. |
[55] | Castillo DV, Figueroa-Guzmán Y, Escobar ML (2006) Brain-derived neurotrophic factor enhances conditioned taste aversion retention. Brain Res 1067: 250-255. doi: 10.1016/j.brainres.2005.10.085 |
[56] | Bi AL, Wang Y, Zhang S, et al. (2015) Myosin II regulates actin rearrangement-related structural synaptic plasticity during conditioned taste aversion memory extinction. Brain Struct Funct 220: 813-825. doi: 10.1007/s00429-013-0685-5 |
[57] | Barki-Harrington L, Elkobi A, Tzabary T, et al. (2009) Tyrosine phosphorylation of the 2B subunit of the NMDA receptor is necessary for taste memory formation. J Neurosci 29: 9219-9226. doi: 10.1523/JNEUROSCI.5667-08.2009 |
[58] | Miranda MI, Rangel-Hernández JA, Vera-Rivera G, et al. (2017) The role of dopamine D2 receptors in the nucleus accumbens during taste-aversive learning and memory extinction after long-term sugar consumption. Neuroscience 359: 142-150. doi: 10.1016/j.neuroscience.2017.07.009 |
[59] | Slouzkey I, Rosenblum K, Maroun M (2013) Memory of conditioned taste aversion is erased by inhibition of PI3K in the insular cortex. Neuropsychopharmacology 38: 1143-1153. doi: 10.1038/npp.2013.20 |